Samarium(II) di-iodide induced reductive coupling of α,β-unsaturated esters with carbonyl compounds leading to a facile synthesis of γ-lactone

1988 ◽  
pp. 1669-1675 ◽  
Author(s):  
Shin-ichi Fukuzawa ◽  
Akira Nakanishi ◽  
Tatsuo Fujinami ◽  
Shizuyoshi Sakai
Keyword(s):  
Carbonyl Compounds ◽  
Reductive Coupling ◽  
Facile Synthesis ◽  
Unsaturated Esters

Photoinduced umpolung addition of carbonyl compounds with α,β-unsaturated esters enables the polysubstituted γ-lactone formation

2020 ◽  
Vol 56 (87) ◽  
pp. 13441-13444
Author(s):  
Jia-Yi Gu ◽  
Wei Zhang ◽  
Seth R. Jackson ◽  
Yan-Hong He ◽  
Zhi Guan
Keyword(s):  
Carbonyl Compounds ◽  
Reductive Coupling ◽  
Ketyl Radical ◽  
Unsaturated Esters ◽  
Radical Intermediates

Photoinduced reductive coupling of carbonyl compounds and α,β-unsaturated esters via ketyl radical intermediates for the synthesis of γ-lactones is described.

A FACILE SYNTHESIS AND REACTIONS OF AMINO SELENOLO[2,3-b]PYRIDINE CARBOXYLATE

2015 ◽  
Vol 12 (1) ◽  
pp. 3910-3918 ◽  
Author(s):  
Dr Remon M Zaki ◽  
Prof Adel M. Kamal El-Dean ◽  
Dr Nermin A Marzouk ◽  
Prof Jehan A Micky ◽  
Mrs Rasha H Ahmed
Keyword(s):  
Biological Activity ◽  
Carbonyl Compounds ◽  
Mass Spectra ◽  
The Other ◽  
Pyridine Derivatives ◽  
Facile Synthesis ◽  
High Biological Activity ◽  
Basic Hydrolysis ◽  
Pyridine Carboxylate ◽  
Hydrolysis Of

 Incorporating selenium metal bonded to the pyridine nucleus was achieved by the reaction of selenium metal with 2-chloropyridine carbonitrile 1 in the presence of sodium borohydride as reducing agent. The resulting non isolated selanyl sodium salt was subjected to react with various α-halogenated carbonyl compounds to afford the selenyl pyridine derivatives 3a-f  which compounds 3a-d underwent Thorpe-Ziegler cyclization to give 1-amino-2-substitutedselenolo[2,3-b]pyridine compounds 4a-d, while the other compounds 3e,f failed to be cyclized. Basic hydrolysis of amino selenolo[2,3-b]pyridine carboxylate 4a followed by decarboxylation furnished the corresponding amino selenolopyridine compound 6 which was used as a versatile precursor for synthesis of other heterocyclic compound 7-16. All the newly synthesized compounds were established by elemental and spectral analysis (IR, 1H NMR) in addition to mass spectra for some of them hoping these compounds afforded high biological activity.

ChemInform Abstract: Reductive Coupling of Carbonyl Compounds to Pinacols with Zinc in THF-Saturated Aqueous Ammonium Chloride.

ChemInform ◽  
2010 ◽  
Vol 32 (41) ◽  
pp. no-no
Author(s):  
Rahim Hekmatshoar ◽  
Issa Yavari ◽  
Yahya S. Beheshtiha ◽  
Majid M. Heravi
Keyword(s):  
Ammonium Chloride ◽  
Carbonyl Compounds ◽  
Reductive Coupling

ChemInform Abstract: REDUCTIVE COUPLING OF CARBONYL COMPOUNDS TO PINACOLS BY USING LOW-VALENT CERIUM

1982 ◽  
Vol 13 (31) ◽  
Author(s):  
T. IMAMOTO ◽  
T. KUSUMOTO ◽  
Y. HATANAKA ◽  
M. YOKOYAMA
Keyword(s):  
Carbonyl Compounds ◽  
Reductive Coupling ◽  
Low Valent
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