The reaction of benzoyl isothiocyanate with hydrazine derivatives. Part I. Reaction with some alkyl hydrazines

1967 ◽  
pp. 92 ◽  
Author(s):  
G. J. Durant
Keyword(s):  
Hydrazine Derivatives ◽  
Benzoyl Isothiocyanate

The Reactions of Substituted Germyl- and Silylhydrazines with BX3 and CY2 Acceptor Species

1972 ◽  
Vol 50 (4) ◽  
pp. 562-566 ◽  
Author(s):  
L. K. Peterson ◽  
K. I. Thé
Keyword(s):  
Molecular Weight ◽  
Nitrogen Atom ◽  
Low Temperatures ◽  
Adduct Formation ◽  
Steric Effects ◽  
Reaction Products ◽  
Hydrazine Derivatives ◽  
Basic Catalysts ◽  
Series Of Experiments ◽  
Electronic And Steric Effects

Boron trimethyl reacts with each of the organometalloid-hydrazine derivatives Me2NN(R)GeMe3 (R = H, Me, SiMe3) except Me2NN(SiMe3)GeMe3, and with Me2NNHSiMe3, forming 1:1 adducts. With Me2NN(SiMe3)GeMe3 and BMe3, no adduct was formed even at low temperatures. On the basis of p.m.r. spectra, the metalloid-substituted nitrogen atom rather than the terminal nitrogen, is indicated as the basic center at which adduct formation occurs. With BF3, the Si—N and Ge—N bonds of the hydrazine derivatives were cleaved, again indicating attack at the central nitrogen atom. In a series of experiments involving CY2 (Y = O, S) and Me2NN(R)MMe3 (R = H, Me, SiMe3; M = Si, Ge), reaction occurred readily for R = H, but less readily for R = Me and for the compound Me2NN(GeMe3)2, while no reaction was observed for the compounds Me2NN(SiMe3)2 and Me2NN(SiMe3)GeMe3, even when heat or basic catalysts were employed. Reaction products, carbamate and thiocarbamate derivatives, Me2NN(R)C(Y)YMMe3, were characterized on the basis molecular weight, i.r., p.m.r., and mass spectroscopy, and m.p. data. Ease of formation is discussed in terms of electronic and steric effects.

N 1-{4-[(10S)-Dihydroartemisinin-10-oxyl]}phenylmethylene-N 2-(2-methylquinoline-4-yl)hydrazine derivatives as antiplasmodial falcipain-2 inhibitors

2011 ◽  
Vol 21 (10) ◽  
pp. 3073-3079 ◽  
Author(s):  
Wei Luo ◽  
Wei-Qiang Lu ◽  
Kun-Qiang Cui ◽  
Yang Liu ◽  
Jian Wang ◽  
...  
Keyword(s):  
Hydrazine Derivatives

ChemInform Abstract: Addition of Hydrazine to 4,7-Dihydro[1,2,4]triazolo[1,5-a]pyrimidines: Hydrazine Derivatives of 4,5,6,7-Tetrahydro[1,2,4]triazolo[1,5-a]pyrimidine.

ChemInform ◽  
2010 ◽  
Vol 41 (16) ◽  
Author(s):  
Sergey A. Komykhov ◽  
Konstantin S. Ostras ◽  
Kyryl M. Kobzar ◽  
Vladimir I. Musatov ◽  
Sergey M. Desenko
Keyword(s):  
Hydrazine Derivatives ◽  
Derivatives Of
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