Chromatographic study on stepwise aggregation patterns of zwitterionic derivatives of cholic acid

1993 ◽  
Vol 89 (24) ◽  
pp. 4355 ◽  
Author(s):  
Noriaki Funasaki ◽  
Ryota Ueshiba ◽  
Sakae Hada ◽  
Saburo Neya
Keyword(s):  
Cholic Acid ◽  
Chromatographic Study ◽  
Derivatives Of

Investigation of new acyloxy derivatives of cholic acid and their esters as drug absorption modifiers

Steroids ◽  
2011 ◽  
Vol 76 (10-11) ◽  
pp. 1082-1097 ◽  
Author(s):  
Lech Mrózek ◽  
Lenka Dvořáková ◽  
Zuzana Mandelová ◽  
Lucie Rárová ◽  
Anna Řezáčová ◽  
...  
Keyword(s):  
Cholic Acid ◽  
Drug Absorption ◽  
Derivatives Of

A chromatographic study of certain derivatives of quinoxaline N-oxide. Part II

1968 ◽  
Vol 2 (10) ◽  
pp. 569-571
Author(s):  
E. M. Granik ◽  
A. A. Chemerisskaya
Keyword(s):  
Chromatographic Study ◽  
Derivatives Of

ChemInform Abstract: Short Syntheses of Triamine Derivatives of Cholic Acid.

ChemInform ◽  
2010 ◽  
Vol 30 (23) ◽  
pp. no-no
Author(s):  
Chunhong Li ◽  
Atiq-ur-Rehman Atiq-ur-Rehman ◽  
N. Kent Dalley ◽  
Paul B. Savage
Keyword(s):  
Cholic Acid ◽  
Derivatives Of

Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1

2019 ◽  
Vol 400 (5) ◽  
pp. 625-628 ◽  
Author(s):  
Linbing Fan ◽  
Jan Felix Joseph ◽  
Pradeepraj Durairaj ◽  
Maria Kristina Parr ◽  
Matthias Bureik
Keyword(s):  
Cytochrome P450 ◽  
Cholic Acid ◽  
Chenodeoxycholic Acid ◽  
Test System ◽  
Cytochrome P450 Enzyme ◽  
Human Cytochrome ◽  
P450 Enzyme ◽  
Derivatives Of ◽  
Human Cytochrome P450 Enzyme

Abstract The human cytochrome P450 enzyme CYP8B1 is a crucial regulator of the balance of cholic acid (CA) and chenodeoxycholic acid (CDCA) in the liver. It was previously shown to catalyze the conversion of 7α-hydroxycholest-4-en-3-one, a CDCA precursor, to 7α,12α-dihydroxycholest-4-en-3-one, which is an intermediate of CA biosynthesis. In this study we demonstrate that CYP8B1 can also convert CDCA itself to CA. We also show that five derivatives of luciferin are metabolized by CYP8B1 and established a rapid and convenient inhibitor test system. In this way we were able to identify four new CYP8B1 inhibitors, which are aminobenzotriazole, exemestane, ketoconazole and letrozole.

Synthesis and cytotoxicity of A-homo-lactam derivatives of cholic acid and 7-deoxycholic acid

Steroids ◽  
2011 ◽  
Vol 76 (7) ◽  
pp. 690-694 ◽  
Author(s):  
Yanmin Huang ◽  
Sijing Chen ◽  
Jianguo Cui ◽  
Chunfang Gan ◽  
Zhiping Liu ◽  
...  
Keyword(s):  
Cholic Acid ◽  
Deoxycholic Acid ◽  
Derivatives Of

Gas chromatographic study of acetyl derivatives of chlorinated 4-hydroxybenzaldehydes

1982 ◽  
Vol 15 (6) ◽  
pp. 364-366 ◽  
Author(s):  
J. Knuutinen ◽  
E. Kolehmainen ◽  
J. Tarhanen ◽  
J. Salovaara ◽  
M. Lahtiperä
Keyword(s):  
Chromatographic Study ◽  
Derivatives Of
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