Pulse-radiolysis study of the effect of pH on the one-electron reduction potentials of lumichrome derivatives

1985 ◽  
Vol 81 (5) ◽  
pp. 1225 ◽  
Author(s):  
Paul F. Heelis ◽  
Barry J. Parsons ◽  
Glyn O. Phillips ◽  
Edward J. Land ◽  
A. John Swallow
Keyword(s):  
Pulse Radiolysis ◽  
Effect Of Ph ◽  
Reduction Potentials ◽  
Electron Reduction ◽  
The One

scholarly journals One-Electron Reduction Potentials: Calibration of Theoretical Protocols for Morita–Baylis–Hillman Nitroaromatic Compounds in Aprotic Media

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2129 ◽  
Author(s):  
Amauri Francisco da Silva ◽  
Antonio João da Silva Filho ◽  
Mário Vasconcellos ◽  
Otávio Luís de Santana
Keyword(s):  
Cyclic Voltammetry ◽  
Biological Activity ◽  
Chemical Structure ◽  
Reduction Potential ◽  
Chemical Reactivity ◽  
Nitroaromatic Compounds ◽  
Reduction Potentials ◽  
Electron Reduction ◽  
The One ◽  
Antileishmanial Activities

Nitroaromatic compounds—adducts of Morita–Baylis–Hillman (MBHA) reaction—have been applied in the treatment of malaria, leishmaniasis, and Chagas disease. The biological activity of these compounds is directly related to chemical reactivity in the environment, chemical structure of the compound, and reduction of the nitro group. Because of the last aspect, electrochemical methods are used to simulate the pharmacological activity of nitroaromatic compounds. In particular, previous studies have shown a correlation between the one-electron reduction potentials in aprotic medium (estimated by cyclic voltammetry) and antileishmanial activities (measured by the IC50) for a series of twelve MBHA. In the present work, two different computational protocols were calibrated to simulate the reduction potentials for this series of molecules with the aim of supporting the molecular modeling of new pharmacological compounds from the prediction of their reduction potentials. The results showed that it was possible to predict the experimental reduction potential for the calibration set with mean absolute errors of less than 25 mV (about 0.6 kcal·mol−1).

The one-electron reduction of a multi-centred iron(III) polyoxometallate. A pulse radiolysis study

2011 ◽  
Vol 14 (9) ◽  
pp. 1390-1392 ◽  
Author(s):  
Inna Popivker ◽  
Israel Zilbermann ◽  
Eric Maimon ◽  
Haim Cohen ◽  
Dan Meyerstein
Keyword(s):  
Pulse Radiolysis ◽  
Electron Reduction ◽  
The One

The one-electron reduction potentials of NAD

1980 ◽  
Vol 590 (2) ◽  
pp. 273-276 ◽  
Author(s):  
John A. Farrington ◽  
Edward J. Land ◽  
A.John Swallow
Keyword(s):  
Reduction Potentials ◽  
Electron Reduction ◽  
The One

One-electron reduction potentials of 5-indoxyl radicals: a pulse radiolysis and laser photolysis study

1990 ◽  
Vol 94 (9) ◽  
pp. 3583-3588 ◽  
Author(s):  
Slobodan V. Jovanovic ◽  
Steen. Steenken ◽  
Michael G. Simic
Keyword(s):  
Pulse Radiolysis ◽  
Laser Photolysis ◽  
Reduction Potentials ◽  
Electron Reduction

Electrochemical properties and catalytic reactivity of cobalt complexes with redox-active meso-substituted porphycene ligands

2020 ◽  
Vol 24 (01n03) ◽  
pp. 90-97 ◽  
Author(s):  
Taro Koide ◽  
Zihan Zhou ◽  
Ning Xu ◽  
Yoshio Yano ◽  
Toshikazu Ono ◽  
...  
Keyword(s):  
Reduction Potential ◽  
Energy Levels ◽  
Cobalt Complexes ◽  
Alkyl Halides ◽  
Reduction Potentials ◽  
Positive Side ◽  
Redox Active ◽  
Catalytic Reactivity ◽  
Electron Reduction ◽  
The One

The cobalt complexes of meso-aryl substituted porphycenes were synthesized and characterized. The reduction potentials of the complexes were shifted to the positive side depending on the strength of the electron-withdrawing properties of the meso-substituents, while the optical properties, such as the absorption spectra of these complexes, were similar. This suggests that the energy levels of the molecular orbitals of the complexes were changed by the meso-substituents while the gaps of the orbitals were not significantly changed. The one-electron reduction of the complex did not afford the Co(I) species, but the ligand-reduced radical anion, which was characterized by electrospectrochemistry. The generated ligand-reduced species reacted with alkyl halides to form the Co(III)-alkyl complex. As a result, the reduction potential of the electrolytic reaction could be directly controlled by the substituents of the porphycene. The catalytic reaction with trichloromethylbenzene was also performed and it was found that the ratio of the obtained products was changed by the reduction potentials of the catalyst, [Formula: see text]. the cobalt porphycenes.

scholarly journals Reduction of ferric haemoproteins by tetrahydropterins: a kinetic study

2005 ◽  
Vol 392 (3) ◽  
pp. 583-587 ◽  
Author(s):  
Chantal Capeillere-Blandin ◽  
Delphine Mathieu ◽  
Daniel Mansuy
Keyword(s):  
Electron Transfer ◽  
Cytochrome C ◽  
Cytochrome B5 ◽  
Reduction Rate ◽  
Cation Radical ◽  
Order Reduction ◽  
Reduction Potentials ◽  
Electron Reduction ◽  
The One

We previously showed that one-electron transfer from tetrahydropterins to iron porphyrins is a very general reaction, with formation of an intermediate cation radical similar to the one detected in NO synthase. As a model reaction, the rates of reduction of eight haemoproteins by diMePH4 (6,7-dimethyltetrahydropterin) have been studied and correlated with their one-electron reduction potentials, Em (FeIII/FeII). On the basis of kinetic data analyses, a bimolecular collisional mechanism is proposed for the electron transfer from diMePH4 to ferrihaemoproteins. Haemoproteins with reduction potentials below −160 mV were shown not to be reduced by diMePH4 to the corresponding ferrohaemoproteins. For haemoproteins with reduction potentials more positive than −160 mV, such as chloroperoxidase, cytochrome b5, methaemoglobin and cytochrome c, there was a good correlation between the second-order reduction rate constant and the redox potential, Em (FeIII/FeII):The rate of reduction of cytochrome c by BH4 [(6R)-5,6,7,8-tetrahydrobiopterin] was determined to be similar to that of the reduction of cytochrome c by diMePH4. These results confirm the role of tetrahydropterins as one-electron donors to FeIII porphyrins.

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