13C nuclear magnetic resonance studies of the binding of alkali and alkaline earth metal salts to amides

1980 ◽  
Vol 76 (0) ◽  
pp. 1008 ◽  
Author(s):  
Ch. Pulla Rao ◽  
Padmanabhan Balaram ◽  
C. N. Ramachandra Rao
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Alkaline Earth ◽  
Earth Metal ◽  
Metal Salts ◽  
Alkaline Earth Metal ◽  
Magnetic Resonance Studies ◽  
13C Nuclear Magnetic Resonance ◽  
Nuclear Magnetic

Nuclear magnetic resonance and mass spectrometry studies of 2′,3′,5′-O-triacetylguanosine self-assembly in the presence of alkaline earth metal ions (Ca2+, Sr2+, Ba2+)

2011 ◽  
Vol 89 (7) ◽  
pp. 835-844 ◽  
Author(s):  
Irene C.M. Kwan ◽  
Yi-Min She ◽  
Gang Wu
Keyword(s):  
Mass Spectrometry ◽  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Metal Ions ◽  
Self Assembly ◽  
Alkaline Earth ◽  
Earth Metal ◽  
Alkaline Earth Metal ◽  
Alkaline Earth Metal Ions ◽  
Nuclear Magnetic

We report structural determination of cation-templated self-assembly of a guanosine derivative, 2′,3′,5′-O-triacetylguanosine (TAG), in the presence of three alkaline earth metal ions (Ca2+, Sr2+, and Ba2+) in CDCl3. Using a combination of nuclear magnetic resonance (NMR) and electrospray ionization mass spectrometry (ESI-MS) methods, we have found that TAG molecules form discrete octamers in the form of [TAG]8M2+ (M2+ = Ca2+, Sr2+, and Ba2+), which is composed of two G-quartets and a sandwiched metal ion. We have determined the ability of the three alkaline earth metal ions to promote TAG self-assembly (relative binding affinity) to be Sr2+ ≫ Ba2+ > Ca2+. More importantly, we have used two-dimensional (2D) NMR methods to determine the structural details of [TAG]8Sr2+. In particular, we found that each octamer consists of an all-anti G-quartet stacking on top of an all-syn G-quartet in a tail-to-head fashion with a twist angle of 45° between the two G-quartets. This TAG octamer structure represents a unique case quite different from other lipophilic guanosine octamers reported in the literature.

X-Ray crystallographic and 13C nuclear magnetic resonance studies of 3,4,5,6-tetrahydro-2H-1,3,4-oxadiazin-2-ones derived from ephedrine and pseudoephedrine

Tetrahedron ◽  
2001 ◽  
Vol 57 (49) ◽  
pp. 9789-9798 ◽  
Author(s):  
Shawn R Hitchcock ◽  
George P Nora ◽  
David M Casper ◽  
Michael D Squire ◽  
Christopher D Maroules ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Magnetic Resonance Studies ◽  
X Ray ◽  
13C Nuclear Magnetic Resonance ◽  
Nuclear Magnetic

13C Nuclear Magnetic Resonance Studies of Organometallic Compounds. V. Di- and Trimethylplatinum(IV) Derivatives

1974 ◽  
Vol 52 (10) ◽  
pp. 1973-1982 ◽  
Author(s):  
Howard Charles Clark ◽  
Leo Ernest Manzer ◽  
John Edward Henry Ward
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Organometallic Compounds ◽  
Methyl Groups ◽  
Magnetic Resonance Studies ◽  
13C Nuclear Magnetic Resonance ◽  
Cis And Trans ◽  
Nuclear Magnetic

The 13C n.m.r. parameters for thirteen di- and trimethylplatinum(IV) derivatives have been obtained. It is shown that the 13C shieldings and 1JPtC and 2JPtCH values of methyl groups both cis and trans to varied ligands consistently follow trends similar to those found for related methylplatinum(II) derivatives.

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