Photoluminescence properties of quinary Ag–(In,Ga)–(S,Se) quantum dots with a gradient alloy structure for in vivo bioimaging

2021 ◽  
Author(s):  
Nurmanita Rismaningsih ◽  
Hiroki Yamauchi ◽  
Tatsuya Kameyama ◽  
Takahisa Yamamoto ◽  
Saho Morita ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Band Edge ◽  
Photoluminescence Properties ◽  
Alloy Structure ◽  
Near Ir

Mixed-anion Ag–(In,Ga)–(S,Se) QDs exhibited a tunable band-edge PL peak with the S/Se ratio and had superior durability for near-IR in vivo bioimaging in comparison with single anion counterparts.

Tailored Photoluminescence Properties of Ag(In,Ga)Se2 Quantum Dots for Near-Infrared In Vivo Imaging

2020 ◽  
Vol 3 (4) ◽  
pp. 3275-3287 ◽  
Author(s):  
Tatsuya Kameyama ◽  
Hiroki Yamauchi ◽  
Takahisa Yamamoto ◽  
Toshiki Mizumaki ◽  
Hiroshi Yukawa ◽  
...  
Keyword(s):  
Quantum Dots ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Photoluminescence Properties

Rare‐Earth Metal Ions Doped Graphene Quantum Dots for Near‐IR In Vitro/In Vivo/Ex Vivo Imaging Applications

2020 ◽  
Vol 8 (21) ◽  
pp. 2000897 ◽  
Author(s):  
Md. Tanvir Hasan ◽  
Roberto Gonzalez‐Rodriguez ◽  
Ching‐Wei Lin ◽  
Elizabeth Campbell ◽  
Satvik Vasireddy ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Rare Earth ◽  
Ex Vivo ◽  
Graphene Quantum Dots ◽  
Earth Metal ◽  
Near Ir ◽  
Doped Graphene ◽  
Ex Vivo Imaging

scholarly journals Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging

2018 ◽  
Vol 115 (26) ◽  
pp. 6590-6595 ◽  
Author(s):  
Mingxi Zhang ◽  
Jingying Yue ◽  
Ran Cui ◽  
Zhuoran Ma ◽  
Hao Wan ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Fluorescence Imaging ◽  
Lead Sulfide ◽  
Critical Role ◽  
Deep Tissue ◽  
Blood Flows ◽  
Near Ir ◽  
Tissue Fluorescence

With suppressed photon scattering and diminished autofluorescence, in vivo fluorescence imaging in the 1,500- to 1,700-nm range of the near-IR (NIR) spectrum (NIR-IIb window) can afford high clarity and deep tissue penetration. However, there has been a lack of NIR-IIb fluorescent probes with sufficient brightness and aqueous stability. Here, we present a bright fluorescent probe emitting at ∼1,600 nm based on core/shell lead sulfide/cadmium sulfide (CdS) quantum dots (CSQDs) synthesized in organic phase. The CdS shell plays a critical role of protecting the lead sulfide (PbS) core from oxidation and retaining its bright fluorescence through the process of amphiphilic polymer coating and transferring to water needed for imparting aqueous stability and compatibility. The resulting CSQDs with a branched PEG outer layer exhibited a long blood circulation half-life of 7 hours and enabled through-skin, real-time imaging of blood flows in mouse vasculatures at an unprecedented 60 frames per second (fps) speed by detecting ∼1,600-nm fluorescence under 808-nm excitation. It also allowed through-skin in vivo confocal 3D imaging of tumor vasculatures in mice with an imaging depth of ∼1.2 mm. The PEG-CSQDs accumulated in tumor effectively through the enhanced permeation and retention effect, affording a high tumor-to-normal tissue ratio up to ∼32 owing to the bright ∼1,600-nm emission and nearly zero autofluorescence background resulting from a large ∼800-nm Stoke’s shift. The aqueous-compatible CSQDs are excreted through the biliary pathway without causing obvious toxicity effects, suggesting a useful class of ∼1,600-nm emitting probes for biomedical research.

Trends in Nanotechnology for in vivo Cancer Diagnosis: Products and Patents

2020 ◽  
Vol 26 (18) ◽  
pp. 2167-2181
Author(s):  
Tatielle do Nascimento ◽  
Melanie Tavares ◽  
Mariana S.S.B. Monteiro ◽  
Ralph Santos-Oliveira ◽  
Adriane R. Todeschini ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Quantum Dots ◽  
Magnetic Resonance ◽  
Metal Nanoparticles ◽  
Cancer Diagnosis ◽  
Imaging Techniques ◽  
Tumor Detection ◽  
Abnormal Growth ◽  
Pharmaceutical Nanotechnology

Background: Cancer is a set of diseases formed by abnormal growth of cells leading to the formation of the tumor. The diagnosis can be made through symptoms’ evaluation or imaging tests, however, the techniques are limited and the tumor detection may be late. Thus, pharmaceutical nanotechnology has emerged to optimize the cancer diagnosis through nanostructured contrast agent’s development. Objective: This review aims to identify commercialized nanomedicines and patents for cancer diagnosis. Methods: The databases used for scientific articles research were Pubmed, Science Direct, Scielo and Lilacs. Research on companies’ websites and articles for the recognition of commercial nanomedicines was performed. The Derwent tool was applied for patent research. Results: This article aimed to research on nanosystems based on nanoparticles, dendrimers, liposomes, composites and quantum dots, associated to imaging techniques. Commercialized products based on metal and composite nanoparticles, associated with magnetic resonance and computed tomography, have been observed. The research conducted through Derwent tool displayed a small number of patents using nanotechnology for cancer diagnosis. Among these patents, the most significant number was related to the use of systems based on metal nanoparticles, composites and quantum dots. Conclusion: Although few systems are found in the market and patented, nanotechnology appears as a promising field for the development of new nanosystems in order to optimize and accelerate the cancer diagnosis.

In Vivo Deep-Brain Structural and Hemodynamic Multiphoton Microscopy Enabled by Quantum Dots

Nano Letters ◽  
2019 ◽  
Vol 19 (8) ◽  
pp. 5260-5265 ◽  
Author(s):  
Hongji Liu ◽  
Xiangquan Deng ◽  
Shen Tong ◽  
Chen He ◽  
Hui Cheng ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Multiphoton Microscopy ◽  
Deep Brain

scholarly journals Crystalline borophene quantum dots and their derivative boron nanospheres

2021 ◽  
Author(s):  
Huiqi Wang ◽  
Duo An ◽  
Mei Wang ◽  
Liwen Sun ◽  
Ying Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Hydrazine Hydrate ◽  
High Power ◽  
Photoluminescence Properties ◽  
Chemical Exfoliation ◽  
One Step

Crystalline borophene quantum dots with two-photo fluorescence and their derivative boron nanospheres with hydrazine hydrate-dependent photoluminescence properties were prepared by efficient high-power sonication method combined with chemical exfoliation and one-step...

Tuning the structural, optical and photoluminescence properties of hybrid perovskite quantum dots by A-site doping

2020 ◽  
Vol 18 ◽  
pp. 100488 ◽  
Author(s):  
Juan Jesús Gallardo ◽  
Eduardo Blanco ◽  
Antonio Sánchez-Coronilla ◽  
José Carlos Pinero ◽  
Javier Navas
Keyword(s):  
Quantum Dots ◽  
Photoluminescence Properties ◽  
Hybrid Perovskite ◽  
Perovskite Quantum Dots ◽  
A Site

scholarly journals Synthesis and Characterization of Polyvinylpyrrolidone-Modified ZnO Quantum Dots and Their In Vitro Photodynamic Tumor Suppressive Action

2021 ◽  
Vol 22 (15) ◽  
pp. 8106
Author(s):  
Tianming Song ◽  
Yawei Qu ◽  
Zhe Ren ◽  
Shuang Yu ◽  
Mingjian Sun ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Photodynamic Therapy ◽  
Inhibitory Effect ◽  
Therapeutic Effects ◽  
In Vivo Experiments ◽  
Potential Applications ◽  
Zno Quantum Dots ◽  
Zno Qds

Despite the numerous available treatments for cancer, many patients succumb to side effects and reoccurrence. Zinc oxide (ZnO) quantum dots (QDs) are inexpensive inorganic nanomaterials with potential applications in photodynamic therapy. To verify the photoluminescence of ZnO QDs and determine their inhibitory effect on tumors, we synthesized and characterized ZnO QDs modified with polyvinylpyrrolidone. The photoluminescent properties and reactive oxygen species levels of these ZnO/PVP QDs were also measured. Finally, in vitro and in vivo experiments were performed to test their photodynamic therapeutic effects in SW480 cancer cells and female nude mice. Our results indicate that the ZnO QDs had good photoluminescence and exerted an obvious inhibitory effect on SW480 tumor cells. These findings illustrate the potential applications of ZnO QDs in the fields of photoluminescence and photodynamic therapy.

The Emission Property of Phosphors LEDs Based on ZnCuInS/ZnSe/ZnS Quantum Dots

2014 ◽  
Vol 989-994 ◽  
pp. 623-625
Author(s):  
Ke Bi ◽  
Wen Yan Liu ◽  
Tian Yue Xu ◽  
Tie Qiang Zhang ◽  
Yu Zhang
Keyword(s):  
Quantum Dots ◽  
Photoluminescence Spectrum ◽  
Stokes Shift ◽  
Core Shell ◽  
Photoluminescence Properties ◽  
Red Emission ◽  
Light Emitting ◽  
Quantum Size ◽  
Gan Led ◽  
Photoluminescence Peak

.In this research, ZnCuInS/ZnSe/ZnS quantum dots (QDs) have been studied as an excellent red emitting source for blue GaN LED because of its non-toxic deep red emmission, and large Stokes shift properties. In the paper ZnCuInS/ZnSe/ZnS core/shell quantum dots were prepared with the particle size of 4.5nm. According to the measurement of photoluminescence spectrum emitted by ZnCuInS/ZnSe/ZnS core/shell quantum dots, the emitting peak of 700 nm and the full was achieved as red emitter.It was found that absorption edge and photoluminescence peak shifted to shorter wavelength with decreasing the nanocrystal size due to quantum size effect.Meanwhile, we were prepared ZnCuInS/ZnSe/ZnS core/shell quantum dot light emitting diodes and their photoluminescence properties were studied. After the suitable bias was applied on the films, increasing the ZnCuInS/ZnSe/ZnS QDs concentration in the blue GaN chips, red emission increased with decreasing LED’s blue light.

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