Fluorescence-based sensors as an emerging tool for anion detection: mechanism, sensory materials and applications

2021 ◽  
Author(s):  
Manoj Kumar Goshisht ◽  
Neetu Tripathi
Keyword(s):  
Great Promise ◽  
Detection Mechanism ◽  
Anion Detection ◽  
Sensing Platforms ◽  
Charged Ions

Negatively charged ions are integral parts of our ecosystem. Fluorescence-based approaches show great promise in terms of developing efficient sensing platforms for anion detection.

Characterization and Optimization of a Tensioned Metastable Fluid Nuclear Particle Sensor Using Laser-Based Profilometry

2015 ◽  
Vol 1 (4) ◽  
Author(s):  
Alexander R. Hagen ◽  
Thomas F. Grimes ◽  
Brian C. Archambault ◽  
Trevor N. Harris ◽  
Rusi P. Taleyarkhan
Keyword(s):  
Homeland Security ◽  
Nuclear Power ◽  
State Of The Art ◽  
Alpha Spectroscopy ◽  
Neutron Detectors ◽  
Detection Mechanism ◽  
Power Monitoring ◽  
Simple Detection ◽  
Nuclear Particle ◽  
Charged Ions

State-of-the-art neutron detectors lack capabilities required by the fields of homeland security, health physics, and even for direct in-core nuclear power monitoring. A new system being developed at Purdue’s Metastable Fluid and Advanced Research Laboratory in conjunction with S/A Labs, LLC provides capabilities that the state-of-the-art lacks, and simultaneously with beta (β) and gamma (γ) blindness, high (>90% intrinsic) efficiency for neutron/alpha spectroscopy and directionality, simple detection mechanism, and lowered electronic component dependence. This system, the tensioned metastable fluid detector (TMFD), provides these capabilities despite its vastly reduced cost and complexity compared with equivalent present day systems. Fluids may be placed at pressures lower than perfect vacuum (i.e., negative), resulting in tensioned metastable states. These states may be induced by tensioning fluids just as one would tension solids. The TMFD works by cavitation nucleation of bubbles resulting from energy deposited by charged ions or laser photon pile-up heating of fluid molecules, which are placed under sufficiently tensioned (negative) pressure states of metastability. The charged ions may be created from neutron scattering or from energetic charged particles such as alphas, alpha recoils, and fission fragments. A methodology has been created to profile the pressures in these chambers by laser-induced cavitation (LIC) for verification of a multiphysics simulation of the chambers. The methodology and simulation together have led to large efficiency gains in the current acoustically tensioned metastable fluid detector (ATMFD) system. This paper describes in detail the LIC methodology and provides background on the simulation it validates.

Characterization and Optimization of a Tensioned Metastable Fluid Nuclear Particle Sensor Using Laser Based Profilimetry

2014 ◽  
Author(s):  
Alexander R. Hagen ◽  
Thomas F. Grimes ◽  
Brian C. Archambault ◽  
Trevor N. Harris ◽  
Rusi P. Taleyarkhan
Keyword(s):  
Homeland Security ◽  
Nuclear Power ◽  
State Of The Art ◽  
Alpha Spectroscopy ◽  
Neutron Detectors ◽  
Detection Mechanism ◽  
Power Monitoring ◽  
Simple Detection ◽  
Nuclear Particle ◽  
Charged Ions

State of the art neutron detectors lack capabilities required by the fields of homeland security, health physics, and even for direct in-core nuclear power monitoring. A new system being developed at Purdue’s Metastable Fluid and Advanced Research Laboratory in conjunction with S/A Labs, LLC provides capabilities the state of the art lacks, and simultaneously with beta (β) and gamma (γ) blindness, high (> 90% intrinsic) efficiency for neutron/alpha spectroscopy and directionality, simple detection mechanism, and lowered electronic component dependence. This system, the Tensioned Metastable Fluid Detector (TMFD) [3], provides these capabilities despite its vastly reduced cost and complexity compared with equivalent present day systems. Fluids may be placed at pressures lower than perfect vacuum (i.e. negative) [4, 5], resulting in tensioned metastable states. These states may be induced by tensioning fluids just as one would tension solids. The TMFD works by cavitation nucleation of bubbles resulting from energy deposited by charged ions or laser photon pileup heating of fluid molecules which are placed under sufficiently tensioned (negative) pressure states of metastability. The charged ions may be created from neutron scattering, or from energetic charged particles such as alphas, alpha recoils, fission fragments, etc. A methodology has been created to profile the pressures in these chambers by lasing, called Laser Induced Cavitation (LIC), for verification of a multiphysics simulation of the chambers. The methodology and simulation together have lead to large efficiency gains in the current Acoustically Tensioned Metastable Fluid Detector (ATMFD) system. This paper describes in detail the LIC methodology and provides background on the simulation it validates.

scholarly journals Alginate Hydrogel-Embedded Capillary Sensor for Quantitative Immunoassay with Naked Eye

Sensors ◽  
2020 ◽  
Vol 20 (17) ◽  
pp. 4831 ◽  
Author(s):  
Wenshu Zheng ◽  
Cen Gao ◽  
Liheng Shen ◽  
Chang Qu ◽  
Xuan Zhang ◽  
...  
Keyword(s):  
Point Of Care ◽  
Great Promise ◽  
Alginate Hydrogel ◽  
Serum Samples ◽  
Virus Surface ◽  
Naked Eye ◽  
Solution Exchange ◽  
Sensing Platforms ◽  
Quantitative Immunoassay ◽  
Immune Sensing

We have developed an alginate hydrogel-embedded capillary sensor (AHCS) for naked eye-based quantification of immunoassay. Alkaline phosphatase (ALP) can modulate gel-sol transformation to increase the permeability of Cu2+-cross-linked alginate hydrogel film in the AHCS, followed by solution exchange into the capillary. Through measuring the length of the liquid phase of the microfluidics in the capillary at a given time, the concentration of the ALP could be quantified with the naked eye. Since ALP is widely applied as a signal reporter for immunoassays, the AHCS could easily accommodate conventional immune sensing platforms. We justify the practicality of AHCS with hepatitis B virus surface antigen (HBsAg) in serum samples and got comparable results with commercialized immunoassay. This AHCS is easy to make and use, effective in cost, and robust in quantification with the naked eye, showing great promise for next generation point-of-care testing.

scholarly journals Performance of a pulsed ion beam with a renewable cryogenically cooled ion source

2008 ◽  
Vol 26 (4) ◽  
pp. 545-554 ◽  
Author(s):  
T.J. Renk ◽  
G.A. Mann ◽  
G.A. Torres
Keyword(s):  
High Purity ◽  
Ion Beam ◽  
Ion Source ◽  
Anode Surface ◽  
Great Promise ◽  
Closed Cycle ◽  
Successful Development ◽  
Singly Charged ◽  
Charged Ions ◽  
Flight Measurements

AbstractFor operation of an ion source in an intense ion beam diode, it is desirable to form a localized and robust source of high purity. A cryogenically operated ion source has great promise, since the ions are formed from a condensed high-purity gas, which has been confined to a relatively thin ice layer on the anode surface. Previous experiments have established the principles of operation of such an ion source, but have been limited in repetitive duration due to the use of short-lived liquid He cooling of the anode surface. We detail here the successful development of a “Cryo-Diode” in which the cooling was achieved with a closed-cycle cryo-pump. This results in an ion source design that can potentially be operated for an indefinite duration. Time-of-flight measurements with Faraday cups indicate that the resultant ion beam is of high-purity, and composed of singly charged ions formed out of the gas frozen out on the anode surface.

Are HOLZ lines kinematic in off-zone-axis orientation?

1993 ◽  
Vol 51 ◽  
pp. 692-693
Author(s):  
J. M. Zuo ◽  
A. L. Weickenmeier ◽  
R. Holmestad ◽  
J. C. H. Spence
Keyword(s):  
Structure Determination ◽  
Standard Procedure ◽  
High Order ◽  
Zone Axis ◽  
Great Promise ◽  
Line Position ◽  
Measured Intensity ◽  
Constant Intensity ◽  
Axis Orientation ◽  
Diffraction Condition

The application of high order reflections in a weak diffraction condition off the zone axis center, including those in high order laue zones (HOLZ), holds great promise for structure determination using convergent beam electron diffraction (CBED). It is believed that in this case the intensities of high order reflections are kinematic or two-beam like. Hence, the measured intensity can be related to the structure factor amplitude. Then the standard procedure of structure determination in crystallography may be used for solving unknown structures. The dynamic effect on HOLZ line position and intensity in a strongly diffracting zone axis is well known. In a weak diffraction condition, the HOLZ line position may be approximated by the kinematic position, however, it is not clear whether this is also true for HOLZ intensities. The HOLZ lines, as they appear in CBED patterns, do show strong intensity variations along the line especially near the crossing of two lines, rather than constant intensity along the Bragg condition as predicted by kinematic or two beam theory.

Development of the UHV-STM

1990 ◽  
Vol 48 (1) ◽  
pp. 322-323
Author(s):  
M. Iwatsuki ◽  
S. Kitamura ◽  
A. Mogami
Keyword(s):  
Surface Science ◽  
Real Space ◽  
Atomic Scale ◽  
Scanning Tunneling ◽  
Great Promise ◽  
Force Microscopy ◽  
Atomic Force ◽  
Stm Image ◽  
Surface Construction ◽  
Very High

Since Binnig, Rohrer and associates observed real-space topographic images of Si(111)-7×7 and invented the scanning tunneling microscope (STM),1) the STM has been accepted as a powerful surface science instrument.Recently, many application areas for the STM have been opened up, such as atomic force microscopy (AFM), magnetic force microscopy (MFM) and others. So, the STM technology holds a great promise for the future.The great advantages of the STM are its high spatial resolution in the lateral and vertical directions on the atomic scale. However, the STM has difficulty in identifying atomic images in a desired area because it uses piezoelectric (PZT) elements as a scanner.On the other hand, the demand to observe specimens under UHV condition has grown, along with the advent of the STM technology. The requirment of UHV-STM is especially very high in to study of surface construction of semiconductors and superconducting materials on the atomic scale. In order to improve the STM image quality by keeping the specimen and tip surfaces clean, we have built a new UHV-STM (JSTM-4000XV) system which is provided with other surface analysis capability.

Behavioral Genetics: Concepts for Research and Practice in Language Development and Disorders

1995 ◽  
Vol 38 (5) ◽  
pp. 1126-1142 ◽  
Author(s):  
Jeffrey W. Gilger
Keyword(s):  
Language Development ◽  
Behavioral Genetics ◽  
State Of The Art ◽  
Genetic Research ◽  
Great Promise ◽  
Behavioral Genetic ◽  
Fine Grained ◽  
Future Goals ◽  
Current State ◽  
Research Designs

This paper is an introduction to behavioral genetics for researchers and practioners in language development and disorders. The specific aims are to illustrate some essential concepts and to show how behavioral genetic research can be applied to the language sciences. Past genetic research on language-related traits has tended to focus on simple etiology (i.e., the heritability or familiality of language skills). The current state of the art, however, suggests that great promise lies in addressing more complex questions through behavioral genetic paradigms. In terms of future goals it is suggested that: (a) more behavioral genetic work of all types should be done—including replications and expansions of preliminary studies already in print; (b) work should focus on fine-grained, theory-based phenotypes with research designs that can address complex questions in language development; and (c) work in this area should utilize a variety of samples and methods (e.g., twin and family samples, heritability and segregation analyses, linkage and association tests, etc.).

REACTIONS OF DOUBLY CHARGED IONS WITH VARIOUS NEUTRALS

1979 ◽  
Vol 40 (C7) ◽  
pp. C7-21-C7-22
Author(s):  
K. Peska ◽  
E. Alge ◽  
H. Villinger ◽  
H. Störi ◽  
W. Lindinger
Keyword(s):  
Doubly Charged Ions ◽  
Doubly Charged ◽  
Charged Ions
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