scholarly journals A review on electrospun magnetic nanomaterials: methods, properties and applications

2021 ◽  
Author(s):  
Yifan Jia ◽  
Congyi Yang ◽  
Xueyang Chen ◽  
Wenqing Xue ◽  
Helena Jayne Hutchins-Crawford ◽  
...  
Keyword(s):  
Magnetic Materials ◽  
Magnetic Nanomaterials ◽  
Advanced Technologies ◽  
Wide Range

Magnetic materials display attractive properties for a wide range of applications. More recently, interest has turned to significantly enhancing their behaviour for advanced technologies, by exploiting the remarkable advantages that...

Advanced Technologies in DNA-based Nanomedicine

2021 ◽  
Vol 15 ◽  
Author(s):  
Ameneh Mohammadi ◽  
Pooria Gill ◽  
Pedram Ebrahimnejad ◽  
Said Abediankenari ◽  
Zahra Kashi
Keyword(s):  
Drug Delivery ◽  
Gene Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Dna Nanostructures ◽  
Medical Sciences ◽  
Rational Engineering ◽  
Advanced Technologies ◽  
Wide Range ◽  
Or Gene

: The application of nanotechnology in medicine and pharmaceutical purpose suggested a novel procedure in the nanotechnology terminology as nanomedicine. There is a wide range of applications for nanotechnology in medicine, such as the use of nanocarriers in drug delivery systems. Recently a remarkable attention to DNA has been made through its amazing functionality and its nature as a nanomaterial in biological systems. Since DNA is a biocompatible, the use of DNA as a nanomaterial in medicine has shown a great perspective of rational engineering of DNA nanostructures. According to new approaches in treatment of diseases in gene levels, gene therapy, using DNA as a nanomedicine possesses an important role in the medical sciences as the researchers published enormous papers and patents in the fields, for instance, the applications of DNA and DNA-based nanostructures as drug or gene nanocarriers, DNA-based diagnostics and DNA nanovasccines. Here, some examples of DNA-based nanomedicine in the patent frame were reviewed.

Generations on New Technologies in Retail Banking in the Context of Knowledge Economy

2019 ◽  
Vol 11 (3) ◽  
pp. 19-33
Author(s):  
Małgorzata Kieżel ◽  
Magdalena Stefańska
Keyword(s):  
Perceived Risk ◽  
Information Society ◽  
New Technologies ◽  
Retail Banking ◽  
Innovative Technology ◽  
Key Factors ◽  
Advanced Technologies ◽  
Wide Range ◽  
Innovative Solutions ◽  
Retail Banks

Together with development of innovative technology, retail banks increasingly and more frequently apply it to create and provide customers value. Such trends are justified in the article, considering the development of information society as well as progressing diversity in customers' preferences. The differences are increasingly stronger, especially if consumers' age representing different generations. The purpose of the article is to identify and evaluate the scope of use of retail banking products based on innovative technologies by customers in total, and while taking into account belonging to three various generations. According to the results of the research, security, lower price and growth of the comfort of use are the key factors to encourage the customers to use innovative solutions in banking. The most important barriers in that area are the costs that occur together with products based on advanced technologies and perceived risk of using unknown earlier services. However, acceptance of technologically advanced products by a wide range of customers depends on generation.

scholarly journals Pathogenetic mechanisms of hirudotherapy and its use in otorhinolaryngology

2020 ◽  
pp. 83-93
Author(s):  
Dmytro I. Zabolotny ◽  
Nina S. Mishchanchuk ◽  
Oleg M. Borisenko ◽  
Andrej L. Bobrov
Keyword(s):  
Circulatory System ◽  
The Body ◽  
Medical Rehabilitation ◽  
Therapeutic Effects ◽  
Pathogenetic Mechanisms ◽  
Saliva Secretion ◽  
Advanced Technologies ◽  
Wide Range ◽  
Active Substances ◽  
Biological Active Substances

Data from studies on the pathogenetic mechanisms of saliva secretion of medical leeches, which is an important producer of unique biological active substances (BAS), is summarized. These substances have a wide range of therapeutic effects, providing a prodounced anti-inflammatory, bacteriostatic, bactericidal, fibrinolytic, neurotropic, regenerative, energetic, immunomodulatory, anti-sclerotic effects. They regulate homeostasis, the circulatory system, lymph flow, all types of metabolic processes in the body and have no analogues in nature. We have presented the results of more than 20 years of effective experience in the use of hirudotherapy in otorhinolaryngology patients for medical, rehabilitation, and health purposes. Promising is the further study and application of hirudotherapy as a type of naturopathy and homeopathy in the 21st century of advanced technologies, significantly changing the conditions of the internal and external environment of the inhabitants of our planet.

scholarly journals Digitalization of inspection activities advanced technologies for competent specialists

2021 ◽  
Vol 6 (2) ◽  
pp. 81-90
Author(s):  
O. P. Taksior ◽  
M. P. Polikarpov
Keyword(s):  
Digital Technologies ◽  
Digital Systems ◽  
Advanced Technologies ◽  
Qualified Personnel ◽  
Wide Range ◽  
Inspection Tasks ◽  
High Degree

The article addresses application of digital technologies in inspection activities. The article describes the scope of use of advanced technologies in practical inspection activities demonstrating a high degree of digitalization and wide range of inspection tasks. Opportunities, restrictions and risks of use of digital systems are analyzed. The article also clarifies unacceptability of “total digitalization” of inspection activities and infeasibility of inspectors’ replacement with digital systems without involvement of qualified personnel.

scholarly journals Remote Actuation of Apoptosis in Liver Cancer Cells via Magneto-Mechanical Modulation of Iron Oxide Nanoparticles

Cancers ◽  
2019 ◽  
Vol 11 (12) ◽  
pp. 1873 ◽  
Author(s):  
Oleg Lunov ◽  
Mariia Uzhytchak ◽  
Barbora Smolková ◽  
Mariia Lunova ◽  
Milan Jirsa ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Liver Cancer ◽  
Cancer Cells ◽  
Iron Oxide Nanoparticles ◽  
Magnetic System ◽  
Short Pulse ◽  
Magnetic Nanomaterials ◽  
Oxide Nanoparticles ◽  
Liver Cancer Cells ◽  
Wide Range

Lysosome-activated apoptosis represents an alternative method of overcoming tumor resistance compared to traditional forms of treatment. Pulsed magnetic fields open a new avenue for controlled and targeted initiation of lysosomal permeabilization in cancer cells via mechanical actuation of magnetic nanomaterials. In this study we used a noninvasive tool; namely, a benchtop pulsed magnetic system, which enabled remote activation of apoptosis in liver cancer cells. The magnetic system we designed represents a platform that can be used in a wide range of biomedical applications. We show that liver cancer cells can be loaded with superparamagnetic iron oxide nanoparticles (SPIONs). SPIONs retained in lysosomal compartments can be effectively actuated with a high intensity (up to 8 T), short pulse width (~15 µs), pulsed magnetic field (PMF), resulting in lysosomal membrane permeabilization (LMP) in cancer cells. We revealed that SPION-loaded lysosomes undergo LMP by assessing an increase in the cytosolic activity of the lysosomal cathepsin B. The extent of cell death induced by LMP correlated with the accumulation of reactive oxygen species in cells. LMP was achieved for estimated forces of 700 pN and higher. Furthermore, we validated our approach on a three-dimensional cellular culture model to be able to mimic in vivo conditions. Overall, our results show that PMF treatment of SPION-loaded lysosomes can be utilized as a noninvasive tool to remotely induce apoptosis.

scholarly journals CONSULTING SERVICES: ESSENCE, KINDS AND MAIN DIRECTIONS OF USE

2017 ◽  
Vol 12 (2) ◽  
pp. 109-115 ◽  
Author(s):  
Гузалия Клычова ◽  
Guzaliya Klychova ◽  
Аугуль Клычова ◽  
Augul Klychova ◽  
Алсу Закирова ◽  
...  
Keyword(s):  
Business Processes ◽  
Raw Materials ◽  
Information Flows ◽  
Highly Qualified ◽  
Economic Activities ◽  
Consulting Services ◽  
Advanced Technologies ◽  
Wide Range ◽  
Consulting Firms ◽  
Main Factors

In modern conditions, characterized by an increase in the scale of information flows and a dynamically changing external environment, one of the main factors, contributing to the effective functioning and development of business, is the possibility of obtaining highly qualified advisory assistance. The conditions of a competitive market form the external and internal circumstances, that cause certain difficulties in the functioning of even strong and developed organizations. Many business processes are affected by fluctuations in prices for raw materials and exchange rates, changes in government policy in relation to any sphere of the economy, decisions that are taken on the international arena. A certain imbalance in the activities of the organization can make a tense relationship between the management structures and subordinates, an arrival of new partners, contractors, buyers and customers. In the event that these problems can not be solved by the organization itself, one of the ways out of this situation can be to apply to a professional consulting firm. At the same time, organizations can resort to the services of consultants in cases when not only problems arise, but also when costs should be optimized, growth rates should be accelerated, and the activity of the administrative apparatus should be regulated. Consulting firms offer both ready-made solutions for the implementation of financial and economic activities, as well as those that are developed individually with the client organization. The essence, types and directions of using consulting services are considered in the article. At present, consulting firms offer a wide range of consulting services, which organizations can take advantage of in the process of their financial and economic activities of any non-standard situations and problems. Attraction of consultants gives significant advantages, as it allows, not holding in staff on a permanent basis highly qualified specialist, to solve arising in the course of work non-standard tasks. This is one of the indicators of the level of implementation in the production and maintenance of advanced technologies. Consulting is the basic trend in the development of organizations and increasing their competitiveness in modern conditions.

scholarly journals Diagnosis and optimization of WWTPs using the PWM library: full-scale experiences

2016 ◽  
Vol 75 (3) ◽  
pp. 518-529 ◽  
Author(s):  
T. Fernández-Arévalo ◽  
I. Lizarralde ◽  
M. Maiza ◽  
S. Beltrán ◽  
P. Grau ◽  
...  
Keyword(s):  
Wastewater Treatment ◽  
Mathematical Models ◽  
Water Resource ◽  
Wastewater Treatment Plants ◽  
Resource Recovery ◽  
Full Scale ◽  
Complete Model ◽  
Model Library ◽  
Advanced Technologies ◽  
Wide Range

Given the shift in perception of wastewater treatment plants as water resource recovery facilities, conventional mathematical models need to be updated. The resource recovery perspective should be applied to new processes, technologies and plant layouts. The number and level of models proposed to date give an overview of the complexity of the new plant configurations and provides a wide range of possibilities and process combinations in order to construct plant layouts. This diversity makes the development of standard, modular and flexible tools and model libraries that allow the incorporation of new processes and components in a straightforward way a necessity. In this regard, the plant-wide modelling (PWM) library is a complete model library that includes conventional and advanced technologies and that allows economic and energetic analyses to be carried out in a holistic way. This paper shows the fundamentals of this PWM library that is built upon the above-mentioned premises and the application of the PWM library in three different full-scale case studies.

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