Spherical and rod shaped mesoporous nanosilicas for cancer-targeted and photosensitizers delivery in photodynamic therapy

Author(s):  
Wioleta Borzęcka ◽  
Patrícia Pereira ◽  
Rosa Fernandes ◽  
Tito Trindade ◽  
Tomás Torres ◽  
...  

Mesoporous silica nanoparticles (MSNPs) have attracted much attention in many biomedical applications. One of the fields in which smart functional nanosystems have found wide application is in cancer treatment. Here,...

RSC Advances ◽  
2020 ◽  
Vol 10 (41) ◽  
pp. 24624-24630
Author(s):  
Gaizhen Kuang ◽  
Qingfei Zhang ◽  
Shasha He ◽  
Ying Liu

We developed a Cur loaded PEGylated mesoporous silica nanoparticle system (MSN-PEG@Cur) for effective photodynamic therapy in cancer treatment.


2019 ◽  
Vol 175 ◽  
pp. 477-486 ◽  
Author(s):  
Chang-Ming Liu ◽  
Guang-Bing Chen ◽  
Hui-Hong Chen ◽  
Jia-Bin Zhang ◽  
Hui-Zhang Li ◽  
...  

2011 ◽  
Vol 123 (48) ◽  
pp. 11627-11631 ◽  
Author(s):  
Magali Gary-Bobo ◽  
Youssef Mir ◽  
Cédric Rouxel ◽  
David Brevet ◽  
Ilaria Basile ◽  
...  

Pharmaceutics ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 432 ◽  
Author(s):  
Rafael R. Castillo ◽  
Daniel Lozano ◽  
María Vallet-Regí

The enormous versatility of mesoporous silica nanoparticles permits the creation of a large number of nanotherapeutic systems for the treatment of cancer and many other pathologies. In addition to the controlled release of small drugs, these materials allow a broad number of molecules of a very different nature and sizes. In this review, we focus on biogenic species with therapeutic abilities (proteins, peptides, nucleic acids, and glycans), as well as how nanotechnology, in particular silica-based materials, can help in establishing new and more efficient routes for their administration. Indeed, since the applicability of those combinations of mesoporous silica with bio(macro)molecules goes beyond cancer treatment, we address a classification based on the type of therapeutic action. Likewise, as illustrative content, we highlight the most typical issues and problems found in the preparation of those hybrid nanotherapeutic materials.


2011 ◽  
Vol 6 (9) ◽  
pp. 2332-2338 ◽  
Author(s):  
Jie Zhu ◽  
Huixiang Wang ◽  
Lei Liao ◽  
Lingzhi Zhao ◽  
Liang Zhou ◽  
...  

2017 ◽  
Vol 12 (13) ◽  
pp. 1465-1469 ◽  
Author(s):  
Prasanna Lakshmi Abbaraju ◽  
Yannan Yang ◽  
Meihua Yu ◽  
Jianye Fu ◽  
Chun Xu ◽  
...  

2010 ◽  
Vol 402 (1-2) ◽  
pp. 221-230 ◽  
Author(s):  
Ouahiba Hocine ◽  
Magali Gary-Bobo ◽  
David Brevet ◽  
Marie Maynadier ◽  
Simon Fontanel ◽  
...  

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