Preparation of thermo-responsive drug carrier consisting of biocompatible triblock copolymer and fullerene

Author(s):  
Kohei Kitano ◽  
Kazuhiko Ishihara ◽  
Shinichi Yusa

A triblock copolymer (PEG-b-PUEM-b-PMPC; EUM) comprising poly(ethylene glycol) (PEG), thermo-responsive poly(2-ureidoethyl methacrylate) (PUEM), and poly(2-(methacryloyloxy)ethyl phosphorylcholine) (PMPC) blocks was synthesized via controlled radical polymerization. PEG and PMPC blocks exhibit hydrophilicity...

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20025-20034 ◽  
Author(s):  
Yuling Li ◽  
Sai Wang ◽  
Dandan Zhu ◽  
Yuling Shen ◽  
Baixiang Du ◽  
...  

Reversibly shell cross-linked micelles based on a lipoic acid (LA) decorated triblock copolymer poly(ethylene glycol)-b-poly(γ-benzyl-l-glutamate)-b-poly(l-phenylalanine) have been developed for efficient intracellular delivery of DOX.


2018 ◽  
Vol 449 ◽  
pp. 15-22 ◽  
Author(s):  
Balkew Zewge Hailemeskel ◽  
Kefyalew Dagnew Addisu ◽  
Adhimoorthy Prasannan ◽  
Shewaye Lakew Mekuria ◽  
Chen-Yu Kao ◽  
...  

2006 ◽  
Vol 103 (4) ◽  
pp. 2695-2702 ◽  
Author(s):  
K. C. Remant Bahadur ◽  
Santosh Aryal ◽  
Shanta Raj Bhattarai ◽  
Myung Seob Khil ◽  
Hak Yong Kim

2016 ◽  
Vol 18 (17) ◽  
pp. 11986-11999 ◽  
Author(s):  
Zelai He ◽  
Ying Sun ◽  
Jun Cao ◽  
Yourong Duan

In a previous study, a novel biodegradable multiblock copolymer, monomethoxy (poly-ethylene glycol)–poly(d,l-lactide-co-glycolide)–poly(l-lysine) (PEAL), was developed as a new drug carrier material.


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