Nanostructural Control of Transparent Hydroxyapatite Nanoparticle Films by Citric Acid Coordination Technique

Author(s):  
Zizhen Liu ◽  
Takuya Kataoka ◽  
Sadaki Samitsu ◽  
Daisuke Kawagoe ◽  
Motohiro Tagaya

Hydroxyapatite (HA), as the main mineral component in hard tissues, has good biocompatibility. In particular, HA films are widely used as bioactive coatings for artificial bones and dental implants in...

2021 ◽  
Vol 22 (3) ◽  
pp. 1067
Author(s):  
Georgios Romanos ◽  
Gerard Fischer ◽  
Rafael Delgado-Ruiz

The objective of this review was to analyze the process of wear of implants leading to the shedding of titanium particles into the peri-implant hard and soft tissues. Titanium is considered highly biocompatible with low corrosion and toxicity, but recent studies indicate that this understanding may be misleading as the properties of the material change drastically when titanium nanoparticles (NPs) are shed from implant surfaces. These NPs are immunogenic and are associated with a macrophage-mediated inflammatory response by the host. The literature discussed in this review indicates that titanium NPs may be shed from implant surfaces at the time of implant placement, under loading conditions, and during implant maintenance procedures. We also discuss the significance of the micro-gap at the implant-abutment interface and the effect of size of the titanium particles on their toxicology. These findings are significant as the titanium particles can have adverse effects on local soft and hard tissues surrounding implants, implant health and prognosis, and even the health of systemic tissues and organs.


Materials ◽  
2019 ◽  
Vol 13 (1) ◽  
pp. 72 ◽  
Author(s):  
Jung-Ju Kim ◽  
Jae-Hyun Lee ◽  
Jeong Chan Kim ◽  
Jun-Beom Lee ◽  
In-Sung Luke Yeo

The stability of peri-implant tissue is essential for the long-term success of dental implants. Although various types of implant connections are used, little is known about the effects of the physical mechanisms of dental implants on the stability of peri-implant tissue. This review summarizes the relevant literature to establish guidelines regarding the effects of connection type between abutments and implants in soft and hard tissues. Soft tissue seals can affect soft tissue around implants. In external connections, micromobility between the abutment and the hex component of the implant, resulting from machining tolerance, can destroy the soft tissue seal, potentially leading to microbial invasion. Internal friction connection implants induce strain on the surrounding bone via implant wall expansion that translates into masticatory force. This strain is advantageous because it increases the amount and quality of peri-implant bone. The comparison of internal and external connections, the two most commonly used connection types, reveals that internal friction has a positive influence on both soft and hard tissues.


1968 ◽  
Vol 35 (2) ◽  
pp. 207-212
Author(s):  
Satoshi Sasaki ◽  
Shigenobu Hara
Keyword(s):  

Coatings ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1012
Author(s):  
Heng Dong ◽  
Hui Liu ◽  
Na Zhou ◽  
Qiang Li ◽  
Guangwen Yang ◽  
...  

Dental implants are widely used in the field of oral restoration, but there are still problems leading to implant failures in clinical application, such as failed osseointegration, marginal bone resorption, and peri-implantitis, which restrict the success rate of dental implants and patient satisfaction. Poor osseointegration and bacterial infection are the most essential reasons resulting in implant failure. To improve the clinical outcomes of implants, many scholars devoted to modifying the surface of implants, especially to preparing different physical and chemical modifications to improve the osseointegration between alveolar bone and implant surface. Besides, the bioactive-coatings to promote the adhesion and colonization of ossteointegration-related proteins and cells also aim to improve the osseointegration. Meanwhile, improving the anti-bacterial performance of the implant surface can obstruct the adhesion and activity of bacteria, avoiding the occurrence of inflammation related to implants. Therefore, this review comprehensively investigates and summarizes the modifying or coating methods of implant surfaces, and analyzes the ossteointegration ability and anti-bacterial characteristics of emerging functional coatings in published references.


Coatings ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 214
Author(s):  
Miquel Punset ◽  
Javi Vilarrasa ◽  
José Nart ◽  
José María Manero ◽  
Begoña Bosch ◽  
...  

Surface topography and physical-chemical properties usually play a key-role in both osseointegration improvement and bacterial colonization reduction over the surface of dental implants. The aim of this study is to compare the chemical and bacteriological behavior of two different acid passivation surface treatments on titanium c.p. grade 3 used for dental implant manufacturing. Surface roughness was evaluated using White Light Interferometry (WLI) in order to determine different roughness parameters such as average roughness (Sa), the spacing parameter (Sm) and the hybrid parameter of surface index area (SIA). Contact angle (CA) and surface free energy (SFE) were evaluated in order to establish the surface wettability of the different groups of samples. Titanium ion-release from the different samples was also been analyzed in Hank’s solution medium at 37 °C by using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) at different immersion times. Bacterial viability adhesion assays were done using S. sanguinis (CECT 480, Spain) as a bacterial strain model of primary colonizer in oral biofilm formation. The bacteria attachment and morphology on Ti surfaces were determined using a live/dead staining method after 4 h of incubation and further analyzed by scanning electron microscope (SEM). Acid passivation surface treatments produced a statistically-significant (p < 0.05) roughness increase in all the evaluated parameters (Sa, Sm, SAI). The treatment with citric acid decreased the static contact angle (CA) and caused an increase in surface free energy (SFE) with a high polarization and oxidizing character. These physical-chemical surface characteristics obtained by means of citric acid passivation caused the bactericidal behavior as it has been proved in bacterial studies.


2021 ◽  
Vol 2 ◽  
Author(s):  
Yinying Qu ◽  
Lin Liu

Titanium is currently the most commonly used material for manufacturing dental implants. However, its potential toxic effects and the gray color have resulted in increasing requests for metal-free treatment options. Zirconia is a type of ceramic materials that has been extensively used in medicine field, such as implant abutments and various joint replacement appliances. Amounts of clinical evaluations have indicated good biocompatibility for zirconia products. Besides, its toothlike color, low affinity for plaque and outstanding mechanical and chemical properties have made it an ideal candidate for dental implants. The aim of this study is to review the laboratory and clinical papers about several kinds of zirconia materials and zirconia surface modification techniques. Although there are plenty of literatures on these topics, most of the researches focused on the mechanical properties of the materials or based on cell and animal experiments. Randomized clinical trials on zirconia materials are still urgently needed to validate their application as dental implants.


2015 ◽  
Vol 659 ◽  
pp. 35-39 ◽  
Author(s):  
Pongporn Moonchaleanporn ◽  
Nuchthana Poolthong ◽  
Ruangdaj Tongsri

The design of engineered bone substitutes takes biocompatibility and mechanical compatibility into account as prerequisite requirements. Titanium (Ti) and hydroxyapatite (HA) with chemical formula of Ca10(PO4)6(OH)2, show good biocompatibility and are known as biomaterials. To combine metal powder (Ti) and ceramic powder (HA) as a composite material with mechanical properties comparable to those of natural bones needs strategy. In this work, powder metallurgy process was employed to produce Ti-HA composites, with nominal HA powder contents in the range of 0-100 vol.%. Mixtures of Ti and HA powders were pressed in a rigid die. Sintering was performed in vacuum atmosphere. The as-sintered specimens were tested on biocompatibility in a human-osteoblast cells. It was found that processing and materials parameters, including compaction pressure, control the composite microstructures and mechanical properties. Laboratory bone tissue culturing showed that a bone tissue could grow on the artificial bones (sintered Ti-HA composites).


MRS Advances ◽  
2015 ◽  
Vol 1 (19) ◽  
pp. 1333-1338 ◽  
Author(s):  
Jilong Wang ◽  
Siheng Su ◽  
Jingjing Qiu

ABSTRACTIn this paper, hydrothermal method has been employed to synthesize oxygen-modified carbon dots (O-CDs) from citric acid and nitrogen and sulfur modified carbon dots (N,S-CDs) from citric acid and cysteine. Both as-prepared carbon dots achieve naked-eye observable blue-green luminescence. Fourier transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) are used to exhibit the chemical composition of carbon dots. The structure and size of both carbon dots are similar via transmission electron microscopy (TEM) and dynamic light scattering (DLS), which indicates that the function of size effect can be neglected in this study. Fluorescence properties, UV-vis absorption and solubility are systemically studied to investigate the influence of surface modification. The N,S-CDs show high quantum yield and excitation independent photoluminescence, however, the O-CDs present low quantum yield and excitation dependent photoluminescence, and both carbon dots achieve strong photo-stability. The cytotoxicity of carbon dots is also performed on U87-MG brain tumor cells, which shows that both carbon dots process good biocompatibility and low toxicity in live cell. The bright cellular imaging photos indicate that both carbon dots have great potential to serve as high quality optical imaging probes.


2018 ◽  
Vol 930 ◽  
pp. 520-525
Author(s):  
L.C. Aranha ◽  
Cristiano Stefano Mucsi ◽  
F.C. Ceoni ◽  
M.C. Alencar ◽  
Jesualdo Luiz Rossi

This paper presents the initial developments of a prototype device intended to perform measurements of the fastening torque in the range bellow 1 N.m – hereby denominated microtorque. The device is intended to yield data for analysis of in vitro torquing and detorquing experiments, for fixation and removing of abutments in dental implants and implants in artificial bones. The analysis of the data acquired allowed the authors to observe characteristic fingerprints or signal signatures associated to the type of abutment or implant under experimentation as well as of the mechanical prototype characteristics. In this paper, two different systems of abutment and implant were analyzed. The correlation between the phenomena associated to the signal fingerprints indicate that the developed measurement protocol may be extended to other implant / abutment systems. The authors suggest that the insertion and removal torque curves evaluated in this study would facilitated the correlation between the abutments stability in actual patients and the dynamical behavior under masticatory function.


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