pH-Sensitive branched β-glucan-modified liposomes for activation of antigen presenting cells and induction of antitumor immunity

2021 ◽  
Author(s):  
Shin Yanagihara ◽  
Nozomi Kasho ◽  
Koichi Sasaki ◽  
Naoto Shironaka ◽  
Yukiya Kitayama ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Cellular Immunity ◽  
Antitumor Immunity ◽  
Antigen Presenting Cells ◽  
Ph Sensitive ◽  
Antigen Delivery ◽  
Antigen Presenting

Induction of cellular immunity is important for effective cancer immunotherapy. Although various antigen carriers for cancer immunotherapy have been developed to date, balancing efficient antigen delivery to antigen presenting cells...

An MRI-visible immunoadjuvant based on hollow Gd2O3 nanospheres for cancer immunotherapy

2020 ◽  
Vol 56 (59) ◽  
pp. 8186-8189
Author(s):  
Xia Li ◽  
Xiupeng Wang ◽  
Atsuo Ito
Keyword(s):  
Cancer Immunotherapy ◽  
Cellular Uptake ◽  
Tumor Antigen ◽  
Signal Intensity ◽  
Antitumor Immunity ◽  
Antigen Presenting Cells ◽  
Ph Dependent ◽  
Antigen Presenting

An MRI-visible immunoadjuvant based on hollow Gd2O3 nanospheres significantly promotes the cellular uptake of a tumor antigen by antigen presenting cells, exhibits pH-dependent alteration of the MR signal intensity and markedly enhances the antitumor immunity.

scholarly journals Multi-Immune Agonist Nanoparticle Therapy Stimulates Type I Interferons to Activate Antigen-Presenting Cells and Induce Antigen-Specific Antitumor Immunity

2021 ◽  
Vol 18 (3) ◽  
pp. 1014-1025
Author(s):  
Elizabeth S. Levy ◽  
Ryan Chang ◽  
Colin R. Zamecnik ◽  
Miqdad O. Dhariwala ◽  
Lawrence Fong ◽  
...  
Keyword(s):  
Antitumor Immunity ◽  
Antigen Presenting Cells ◽  
Type I Interferons ◽  
Type I ◽  
Antigen Presenting

scholarly journals Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Alexei F. Kirkin ◽  
Karine N. Dzhandzhugazyan ◽  
Per Guldberg ◽  
Johnny Jon Fang ◽  
Rikke S. Andersen ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
T Helper Cells ◽  
Antigen Presenting Cells ◽  
T Helper ◽  
Helper Cells ◽  
Antigen Presenting

Chemically modified inulin microparticles serving dual function as a protein antigen delivery vehicle and immunostimulatory adjuvant

2016 ◽  
Vol 4 (3) ◽  
pp. 483-493 ◽  
Author(s):  
Matthew D. Gallovic ◽  
Douglas G. Montjoy ◽  
Michael A. Collier ◽  
Clement Do ◽  
Barbara E. Wyslouzil ◽  
...  
Keyword(s):  
Antigen Presenting Cells ◽  
Protein Antigen ◽  
Dual Function ◽  
Antigen Delivery ◽  
Delivery Vehicle ◽  
Chemically Modified ◽  
Antigen Presenting

An immunostimulatory, acid-sensitive biopolymer (acetalated inulin) was synthesized and fabricated into antigen-loaded microparticles which then passively targeted antigen-presenting cells.

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