Phosphonate/zwitterionic/cationic terpolymer as high-efficiency bactericidal and antifouling coating for metallic substrates

2021 ◽  
Author(s):  
Xiao Zhang ◽  
Li Liu ◽  
Wan Peng ◽  
Xiaohan Dong ◽  
Yahui Gu ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
High Efficiency ◽  
Quaternary Amine ◽  
Block Polymers ◽  
Metallic Substrates ◽  
Antifouling Coating ◽  
Metallic Implants ◽  
New Type ◽  
Critical Challenge

Bacteria associated infection is a critical challenge for metallic implants & devices in biomedical applications. Here, we report the phosphonate/zwitterionic/quaternary amine block polymers as a new type of antifouling and...

scholarly journals Polyphosphorhydrazone-Based Radical Dendrimers

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1230
Author(s):  
Vega Lloveras ◽  
José Vidal-Gancedo
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Biomedical Applications ◽  
Organic Radicals ◽  
Resonance Imaging ◽  
Metal Free ◽  
Antioxidant Agents ◽  
New Type ◽  
Paramagnetic Properties

The search for new biomedical applications of dendrimers has promoted the synthesis of new radical-based molecules. Specifically, obtaining radical dendrimers has opened the door to their use in various fields such as magnetic resonance imaging, as anti-tumor or antioxidant agents, or the possibility of developing new types of devices based on the paramagnetic properties of organic radicals. Herein, we present a mini review of radical dendrimers based on polyphosphorhydrazone, a new type of macromolecule with which, thanks to their versatility, new metal-free contrast agents are being obtained, among other possible applications.

scholarly journals Cryogenic Exfoliation of 2D Stanene Nanosheets for Cancer Theranostics

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Jiang Ouyang ◽  
Ling Zhang ◽  
Leijiao Li ◽  
Wei Chen ◽  
Zhongmin Tang ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Density Functional ◽  
Biomedical Application ◽  
Density Functional Theory Calculations ◽  
Free Electrons ◽  
Functional Theory ◽  
New Approach ◽  
New Type ◽  
Average Size ◽  
Cancer Theranostics

Abstract Stanene (Sn)-based materials have been extensively applied in industrial production and daily life, but their potential biomedical application remains largely unexplored, which is due to the absence of the appropriate and effective methods for fabricating Sn-based biomaterials. Herein, we explored a new approach combining cryogenic exfoliation and liquid-phase exfoliation to successfully manufacture two-dimensional (2D) Sn nanosheets (SnNSs). The obtained SnNSs exhibited a typical sheet-like structure with an average size of ~ 100 nm and a thickness of ~ 5.1 nm. After PEGylation, the resulting PEGylated SnNSs (SnNSs@PEG) exhibited good stability, superior biocompatibility, and excellent photothermal performance, which could serve as robust photothermal agents for multi-modal imaging (fluorescence/photoacoustic/photothermal imaging)-guided photothermal elimination of cancer. Furthermore, we also used first-principles density functional theory calculations to investigate the photothermal mechanism of SnNSs, revealing that the free electrons in upper and lower layers of SnNSs contribute to the conversion of the photo to thermal. This work not only introduces a new approach to fabricate 2D SnNSs but also establishes the SnNSs-based nanomedicines for photonic cancer theranostics. This new type of SnNSs with great potential in the field of nanomedicines may spur a wave of developing Sn-based biological materials to benefit biomedical applications.

Carbon Dots: Synthesis, Properties and Biomedical Applications

2021 ◽  
Author(s):  
Guili Ge ◽  
Lin Li ◽  
Dan Wang ◽  
Mingjian Chen ◽  
Zhaoyang Zeng ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Biomedical Applications ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Synthesis Properties ◽  
New Type ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Physical And Chemical ◽  
And Chemical Properties

Carbon dots (CDs) are a new type of carbon nanomaterial that have unique physical and chemical properties, good biocompatibility, low toxicity, easy surface functionalization, making them widely used in biological...

scholarly journals Parameters and design optimization of the ring piezoelectric ceramic transformer

2015 ◽  
Vol 05 (03) ◽  
pp. 1550022 ◽  
Author(s):  
Jiří Erhart
Keyword(s):  
High Efficiency ◽  
Strong Electric Field ◽  
Resistive Load ◽  
Optimum Load ◽  
Aspect Ratios ◽  
Transformation Ratio ◽  
Ring Segment ◽  
New Type ◽  
Transformation Parameters ◽  
Piezoelectric Ceramic Transformer

Main aim of the presented paper is the theoretical analysis and experimental verification of the transformation parameters for the new type of nonhomogeneously poled ring transformer. The input part is poled in the thickness direction and output part in the radial direction. Two transformer geometries are studied — the input part is at inner ring segment, or it is at the outer ring segment. The optimum electrode size aspect ratios have been found experimentally as [Formula: see text] for the ring with aspect ratio [Formula: see text]. The fundamental as well as higher overtone resonances were studied for the transformation ratio, the optimum resistive load, efficiency and no-load transformation ratio. Higher overtones have better transformation parameters compared to the fundamental resonance. The new type ring transformer exhibits very high transformation ratios up to 200 under no-load and up to 13.4 under a high efficiency of 97% at the optimum load conditions of 10 [Formula: see text]. Strong electric field gradient at the output circuit is applicable for the electrical discharge generation.

A Design of New-Type Pipe Thread Forming Machine Based on Pro/E

2012 ◽  
Vol 628 ◽  
pp. 497-499
Author(s):  
Mei Ling An ◽  
Yan Gui Du
Keyword(s):  
Small Volume ◽  
Structural Model ◽  
High Efficiency ◽  
Design Tool ◽  
Interference Detection ◽  
Light Weight ◽  
Physical Prototype ◽  
New Type ◽  
Movement Simulation

The pipe thread forming machine was innovatively designed in the article, using Pro/E as a design tool, we built the structural model of the pipe thread forming machine and performed interference detection and movement simulation for it, on the basis of this, we made a physical prototype. And our experiment showed the complete machine has the characteristics of high efficiency, tight structure, small volume and light weight, and it was easy to move.

A New Type Component Mode Synthesis Beam Element Based on the Absolute Nodal Coordinate Formulation

2003 ◽  
Author(s):  
Riki Iwai ◽  
Nobuyuki Kobayashi
Keyword(s):  
High Efficiency ◽  
Absolute Nodal Coordinate Formulation ◽  
Mass Matrix ◽  
Synthesis Method ◽  
Beam Element ◽  
Component Mode Synthesis ◽  
Flexible Beam ◽  
Absolute Nodal Coordinate ◽  
New Type ◽  
The Absolute

This paper establishes a new type component mode synthesis method for a flexible beam element based on the absolute nodal coordinate formulation. The deformation of the beam element is defined as the sum of the global shape function and the analytical clamped-clamped beam modes. This formulation leads to a constant and symmetric mass matrix as the conventional absolute nodal coordinate formulation, and makes it possible to reduce the system coordinates of the beam structure which undergoes large rotations and large deformations. Numerical examples show that the excellent agreements are examined between the presented formulation and the conventional absolute nodal coordinate formulation. These results demonstrate that the presented formulation has high accuracy in the sense that the presented solutions are similar to the conventional ones with the less system coordinates and high efficiency in computation.

Surfactant Influence on the Tribological Properties of Bentonite-Based Greases

2005 ◽  
Author(s):  
A. K. Pogosian ◽  
T. R. Martirosyan
Keyword(s):  
Tribological Properties ◽  
High Pressures ◽  
Nano Particles ◽  
Ammonium Salts ◽  
Quaternary Amine ◽  
Wear Properties ◽  
Natural Minerals ◽  
New Type ◽  
Plastic Lubricants ◽  
Properties Of Composites

Development of new type plastic lubricants capable of sustaining high pressures is thus important by using natural minerals. The effect of surfactant ration and structure of thickener nano-particles surfaces on the tribological properties of bentonite-based greases was studied. The best anti-friction and anti-wear properties of plastic lubricants were revealed at the particles modified by quaternary amine and urotropine type ammonium salts, and the necessary ratio for the bentonite particles surface modification by quarterly ammonium salts was revealed, which provide the best tribological properties of composites.

scholarly journals Recent Trends in Covalent and Metal Organic Frameworks for Biomedical Applications

Nanomaterials ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 916 ◽  
Author(s):  
Georges Chedid ◽  
Ali Yassin
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Materials Science ◽  
High Surface ◽  
Metal Organic Frameworks ◽  
Great Promise ◽  
Surface Areas ◽  
Metal Organic ◽  
New Type ◽  
Recent Trends

Materials science has seen a great deal of advancement and development. The discovery of new types of materials sparked the study of their properties followed by applications ranging from separation, catalysis, optoelectronics, sensing, drug delivery and biomedicine, and many other uses in different fields of science. Metal organic frameworks (MOFs) and covalent organic frameworks (COFs) are a relatively new type of materials with high surface areas and permanent porosity that show great promise for such applications. The current study aims at presenting the recent work achieved in COFs and MOFs for biomedical applications, and to examine some challenges and future directions which the field may take. The paper herein surveys their synthesis, and their use as Drug Delivery Systems (DDS), in non-drug delivery therapeutics and for biosensing and diagnostics.

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