Surface chemistry regulates optical properties and cellular interactions of ultrasmall MoS2 quantum dots for biomedical applications

2021 ◽  
Author(s):  
Kangqiang Liang ◽  
Shaohua Qu ◽  
Yixiao Li ◽  
Li-Li Tan ◽  
Li Shang
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Surface Chemistry ◽  
Molybdenum Disulfide ◽  
Biomedical Applications ◽  
Cell Imaging ◽  
Cellular Interactions ◽  
Potential Applications

Molybdenum disulfide quantum dots (MoS2 QDs) have drawn increasing attention owing to their distinct optical properties and potential applications in many fields such as biosensing, photocatalysis and cell imaging. Elucidating...

A Nanoscale Adventure with Silicon: Synthesis, Surface Chemistry, and other Surprises

2015 ◽  
Vol 242 ◽  
pp. 383-390
Author(s):  
Md Hosnay Mobarok ◽  
Tapas K. Purkait ◽  
Jonathan G.C. Veinot
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Surface Chemistry ◽  
Research Group ◽  
Size Dependent ◽  
Earth Abundant ◽  
Potential Applications ◽  
Si Quantum Dots

The preparation and surface chemistry Si quantum dots (SiQDs) are currently an intense focus of research because of their size dependent optical properties and many potential applications. SiQDs offer several advantages over other quantum dots; Si is earth abundant, non-toxic and biocompatible. This account briefly highlights recent advancements made by our research group related to the synthesis, functionalization, surface dependent optical properties and applications of SiQDs.

Recent Advances in the Cancer Bioimaging with Graphene Quantum Dots

2018 ◽  
Vol 25 (25) ◽  
pp. 2876-2893 ◽  
Author(s):  
Keheng Li ◽  
Xinna Zhao ◽  
Gang Wei ◽  
Zhiqiang Su
Keyword(s):  
Quantum Dots ◽  
Biomedical Applications ◽  
Cell Imaging ◽  
Graphene Quantum Dots ◽  
Biological Properties ◽  
Live Cells ◽  
Physical Chemical ◽  
Specific Cancer ◽  
Good Biocompatibility ◽  
Low Cytotoxicity

Fluorescent graphene quantum dots (GQDs) have attracted increasing interest in cancer bioimaging due to their stable photoluminescence (PL), high stability, low cytotoxicity, and good biocompatibility. In this review, we present the synthesis and chemical modification of GQDs firstly, and then introduce their unique physical, chemical, and biological properties like the absorption, PL, and cytotoxicity of GQDs. Finally and most importantly, the recent applications of GQDs in cancer bioimaging are demonstrated in detail, in which we focus on the biofunctionalization of GQDs for specific cancer cell imaging and real-time molecular imaging in live cells. We expect this work would provide valuable guides on the synthesis and modification of GQDs with adjustable properties for various biomedical applications in the future.

scholarly journals Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on their Optical Properties, Toxicity and Pharmacokinetics

2017 ◽  
Vol 23 (3) ◽  
pp. 340-349 ◽  
Author(s):  
Wafa' T. Al-Jamal
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Photodynamic Therapy ◽  
Biomedical Applications ◽  
Semiconductor Nanocrystals ◽  
Organic Dye ◽  
Surface Coatings ◽  
Core Shell ◽  
Biomedical Field

Quantum dots are semiconducting nanocrystals that exhibit extraordinary optical properties. QD have shown higher photostability compared to standard organic dye type probes. Therefore, they have been heavily explored in the biomedical field. This review will discuss the different approaches to synthesis, solubilise and functionalise QD. Their main biomedical applications in imaging and photodynamic therapy will be highlighted. Finally, QD biodistribution profile and in vivo toxicity will be discussed.

Heterogeneous Mixture of Nanoparticles from MoS2 and Ta2O5: Synthesis and Characterization

2018 ◽  
Vol 4 (5) ◽  
pp. 492-496
Author(s):  
Sonali Samantra ◽  
Sirsendu Sekhar Ray
Keyword(s):  
Quantum Dots ◽  
Molybdenum Disulfide ◽  
Metallic Nanoparticles ◽  
Cell Imaging ◽  
Biomedical Application ◽  
Xrd Analysis ◽  
Fluorescence Property ◽  
Application Research ◽  
Edax Analysis ◽  
Vis Spectroscopy

The synthesis of metallic nanoparticles is an active area of academic and application research in nanotechnology. It is also an amalgamating technology which has fascinating multi-disciplinary application in various sections. Nanoparticles has been a conventional but field if we go on further decreasing the size we enter the field of quantum dots (<10 nm) with application in the form of tracers, labels, sensors etc. Molybdenum disulfide and tantalum nanoparticles were synthesized and characterized through FESEM, FTIR, XRD,UV-Vis spectroscopy, spectrofluorimetry, etc. The size of the synthesized nanoparticles as observed in FESEM were found to be in the range of 22 to 50 nm for molybdenum nanoparticle and 34.72 to 72.45 nm in case of tantalum. The EDAX analysis shows the composition of molybdenum nanoparticle as hydrogen(H), molybdenum(Mo), nitrogen(N), oxygen(O) and fluorine(F) with 32.3%, 66.3%, 0.43%, 0.32% and 0.5% respectively. The EDAX analysis show the composition of tantalum nanoparticle as hydrogen(H), tantalum(Ta), oxygen(O), nitrogen(N) and fluorine(F) with 35.9%,50%,4.8%,2.01%,7.17%. The XRD analysis of molybdenum disulfide images indicates the synthesized nanoparticle as crystalline in nature. The average crystallinity was found to be 7.93 nm. Tantalum nanoparticles with a crystallinity of 8.05 and 12.20 nm were observed as [2 0 0] and [1 1 0] planes. Biocompatibility of the synthesized nanoparticles was examined by MTT assay. The spectrofluorometry of the synthesized nanoparticles proves the fluorescence property which is most probably because of the quantum dots. Furthermore, the fluorescence property was also used for the cell imaging. The study is a first its kind to exercise the use of Mo and Ta quantum dots in the field of biomedical application and further work is necessary for optimization and implementation of the nanoparticles in the biological sector.

scholarly journals Facile synthesis of graphene quantum dots from glucan and their application as a deoxidizer and in cell imaging

2020 ◽  
pp. 174751982097393
Author(s):  
Jialu Shen ◽  
Weifeng Chen ◽  
Xiang Liu
Keyword(s):  
Quantum Dots ◽  
Driving Force ◽  
Biomedical Applications ◽  
Cell Imaging ◽  
Size Range ◽  
Graphene Quantum Dots ◽  
Reducing Agents ◽  
Facile Synthesis ◽  
Average Size

A facile and effective route to synthesize graphene quantum dots for cell imaging and as a deoxidizer by using glucan as a precursor is developed. AuNPs are successfully synthesized by mixing of graphene quantum dots and Au(III) salts without any additional reductants. The reducing driving force of these graphene quantum dots is much weaker than that of strong reducing agents such as NaBH4. The sizes of the as-synthesized AuNPs are much larger, with an average size of 15 nm. Notably, this size range is specifically useful and optimal for the application of AuNPs in biomedical applications. In addition, the as-synthesized graphene quantum dots are also successfully applied in cell imaging.

scholarly journals Optical Properties andIn VitroBiological Studies of Oligonucleotide-Modified Quantum Dots

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Valérie A. Gérard ◽  
Mark Freeley ◽  
Eric Defrancq ◽  
Anatoly V. Fedorov ◽  
Yurii K. Gun’ko
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Biological Imaging ◽  
Water Soluble ◽  
Biological Applications ◽  
Potential Applications ◽  
Biochemical Mechanisms

Water-soluble semiconducting nanocrystals or quantum dots (QDs) have attracted much interest in recent years due to their tuneable emission and potential applications in photonics and biological imaging. Fluorescence resonance energy transfer (FRET) processes are very important for elucidating biochemical mechanismsin vitro, and QDs constitute an excellent substrate for this purpose. In this work, new oligonucleotide-functionalised CdTe-based QDs were prepared, characterised and biologically tested. These QDs demonstrated interesting optical properties as well as remarkablein vitrobehaviour and potential for a range of biological applications.

Surface Chemistry in Calcium Capped Carbon Quantum Dots

Nanoscale ◽  
2021 ◽  
Author(s):  
Shihuan Ren ◽  
Bingxu Liu ◽  
Guangting Han ◽  
Haiguang Zhao ◽  
Yuanming Zhang
Keyword(s):  
Quantum Dots ◽  
Optical Properties ◽  
Surface Chemistry ◽  
Carbon Quantum Dots ◽  
Complicated Structure ◽  
Colloidal Carbon

Colloidal carbon quantum dots (C-dots) have attracted a lot of attentions because of their excellent optical properties for various types of applications. While due to the complicated structure in C-dots,...

Silicon Quantum Dots: Promising Theranostic Probes for the Future

2019 ◽  
Vol 20 (12) ◽  
pp. 1255-1263 ◽  
Author(s):  
Vishnu Sankar Sivasankarapillai ◽  
Jobin Jose ◽  
Muhammad Salman Shanavas ◽  
Akash Marathakam ◽  
Md. Sahab Uddin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Quantum Dots ◽  
Optical Properties ◽  
Biomedical Applications ◽  
Medical Diagnostics ◽  
Silicon Quantum Dots ◽  
The Past ◽  
Research Areas ◽  
Semiconductor Crystals ◽  
New Generation

Nanotechnology has emerged as one of the leading research areas involving nanoscale manipulation of atoms and molecules. During the past decade, the growth of nanotechnology has been one of the most important developments that have taken place in the biomedical field. The new generation nanomaterials like Quantum dots are gaining much importance. Also, there is a growing interest in the development of nano-theranostics platforms in medical diagnostics, biomedical imaging, drug delivery, etc. Quantum dots are also known as nanoscale semiconductor crystals, with unique electronic and optical properties. Recently, silicon quantum dots are being studied extensively due to their less-toxic, inert nature and ease of surface modification. The silicon quantum dots (2-10nm) are comparatively stable, having optical properties of silicon nanocrystals. This review focuses on silicon quantum dots and their various biomedical applications like drug delivery regenerative medicine and tissue engineering. Also, the processes involved in their modification for various biomedical applications along with future aspects are discussed.

Exploring novel biomedical applications of rocksalt CdS system with various Eu concentrations (A theoretical study)

2019 ◽  
Vol 33 (31) ◽  
pp. 1950381 ◽  
Author(s):  
M. Junaid Iqbal Khan ◽  
Zarfishan Kanwal ◽  
Juan Liu ◽  
Abera Ijaz ◽  
Nauman Usmani
Keyword(s):  
Optical Properties ◽  
Biomedical Applications ◽  
Theoretical Study ◽  
Computational Study ◽  
Detailed Comparison ◽  
Considerable Change ◽  
Partial Density ◽  
Generalized Gradient ◽  
Generalized Gradient Approximation ◽  
Potential Applications

Current research is a computational study in which we focus on calculating optical properties of Eu-doped Cadmium Sulfide (CdS) system. We employ Perdew–Burke–Ernzerhof (PBE)–generalized gradient approximation (GGA) for accomplishment of our study and we assume various Eu concentrations (3.12%, 6.25% and 9.37%) for doping into host CdS lattice. We substitute Cd atoms with Eu atoms while supercell size is kept fixed ([Formula: see text]. We present a detailed comparison among optical properties of pure CdS and various Eu concentrations. Partial density of states (PDOS) plots reveal hybridization among Cd [Formula: see text]-states, S [Formula: see text]-states and Eu [Formula: see text]-states and because of it, material (CdS:Eu) shows exceptional energy transfer which influences optical spectra and electronic properties. A considerable change in absorption spectra is noted, where in comparison to pure CdS, absorption shows blueshift with increasing Eu concentrations. Our DFT results were found to have great resemblance with existing literature. Addition of Eu into the CdS lattice originates novelty in CdS:Eu system and number of potential applications related to the field of biomedical physics, amperometric biosensors, quantum dots (QDs) sensors, photonics, bioprinting, biosensing luminophores, solar cells and optoelectronics industry may be explored in technological perspectives.

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