scholarly journals Design, preparation, and characterization of CS/PVA/SA hydrogels modified with mesoporous Ag2O/SiO2 and curcumin nanoparticles for green, biocompatible, and antibacterial biopolymer film

RSC Advances ◽  
2021 ◽  
Vol 11 (52) ◽  
pp. 32775-32791
Author(s):  
Ashkan Farazin ◽  
Mehdi Mohammadimehr ◽  
Amir Hossein Ghasemi ◽  
Hossein Naeimi
Keyword(s):  
Curcumin Nanoparticles ◽  
Biopolymer Film

CS/PVA/SA hydrogels modified with mesoporous Ag2O/SiO2 and curcumin nanoparticles for antibacterial biopolymer film.

Preparation and Characterization of Magnetite/PEG Nanoparticles Combined with Curcumin for Drug Delivery Application

2020 ◽  
Vol 855 ◽  
pp. 299-307
Author(s):  
Kusnunnahari ◽  
Ahmad Taufiq ◽  
Arif Hidayat ◽  
Rosy Eko Saputro ◽  
Nandang Mufti
Keyword(s):  
Drug Delivery ◽  
Magnetic Properties ◽  
Drug Release ◽  
Functional Group ◽  
Diffraction Peak ◽  
Excellent Performance ◽  
Curcumin Nanoparticles ◽  
Crystallite Sizes ◽  
Structural And Magnetic Properties

In this work, the synthesis of magnetite/PEG nanoparticles combined with curcumin was conducted by using a simple coprecipitation method. The samples obtained were characterized using XRD, FTIR, and VSM for their structural and magnetic properties. Meanwhile, investigation of the potential as drug delivery agents was done through the drug release test using doxorubicin. The diffraction data analysis presented the addition of curcumin slightly decreased the diffraction peak of magnetite compared to without curcumin. The crystallite sizes of the magnetite/PEG and magnetite/PEG/curcumin were 13.9 nm and 13.7 nm, respectively. The functional group of the magnetite/PEG showed the presence of Fe-O bonds at a wavenumber of 587 cm-1 and 421 cm-1 originating from magnetite. Meanwhile, C-O-C and C-H bonds were observed at wavenumbers of 1108 cm-1 and 2883 cm-1 arising from PEG. Despite Fe-O, C-O-C, and C-H bonds, in magnetite/PEG/curcumin, it was also detected C=O bond at a wavenumber of 1621 cm-1, indicating the presence of the curcumin. Regarding the magnetic properties, the saturation magnetization value of the magnetite/PEG nanoparticles decreased after adding curcumin. Interestingly, the results of the doxorubicin drug release of the magnetite/PEG and magnetite/PEG/curcumin nanoparticles showed excellent performance as drug delivery agents.

scholarly journals Preparation and characterization of PEG-albumin-curcumin nanoparticles intended to treat breast cancer

2016 ◽  
Vol 78 (1) ◽  
pp. 65 ◽  
Author(s):  
J Aukunuru ◽  
R Thadakapally ◽  
Arshiya Aafreen ◽  
M Habibuddin ◽  
S Jogala
Keyword(s):  
Breast Cancer ◽  
Curcumin Nanoparticles ◽  
Treat Breast Cancer

Preparation and characterization of cationic curcumin nanoparticles for improvement of cellular uptake

2012 ◽  
Vol 90 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Jinsong Liu ◽  
Lihua Xu ◽  
Chuantong Liu ◽  
Dafeng Zhang ◽  
Siqian Wang ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Curcumin Nanoparticles

Construction and characterization of curcumin nanoparticles system

2014 ◽  
Vol 16 (3) ◽  
Author(s):  
Weitong Sun ◽  
Yu Zou ◽  
Yaping Guo ◽  
Lu Wang ◽  
Xue Xiao ◽  
...  
Keyword(s):  
Curcumin Nanoparticles

scholarly journals PREPARATION AND CHARACTERIZATION OF CURCUMIN NANOPARTICLES LOADED THERMOSENSITIVE GELATIN - PLURONIC F127 HYDROGEL FOR WOUND HEALING APPLICATION

2019 ◽  
Vol 1 (26) ◽  
pp. 92-101
Author(s):  
Trinh Thi Ngoc Nguyen ◽  
Quyen Ngoc Tran ◽  
Linh Thi Yen Nguyen ◽  
Thinh Tien Nguyen
Keyword(s):  
Wound Healing ◽  
Aqueous Solubility ◽  
Test Tube ◽  
Release Profile ◽  
Pluronic F127 ◽  
Copolymer Solution ◽  
Curcumin Nanoparticles ◽  
Transmission Electron ◽  
Differential Scanning Colorimetry

Curcumin, a natural phenolic compound, is extracted from turmeric exhibiting several biomedical activities. Unfortunately, less aqueous solubility causesl  drawback in medicinal application. This study introduces a method in order to produce a biomaterial containing high content of curcumin nanoparticles, which can overcome curcumin’s poor dissolution and wound healing. This method uses a thermo-reversible pluronic F127-grafted gelatin (GP) which play the role as surfactant to disperse and protect nanocurcumin from aggregation. The synthetic GP copolymer was identified via 1H NMR. Thermal transition behavior was identified under test tube inversion and differential scanning colorimetry (DSC). The synthesized curcumin size was characterized by Transmission Electron  Microscopy (TEM) and Dynamic Light Scattering (DLS), which indicated that the size of nanocurcumin significantly varied ranging from 7 to 285 nm according to the amount of feeded curcurmin. The nanocurcumin-dispersed GP copolymer solution forms the nanocomposite hydrogel when warmed up to 36.27 °C. Release profile indicated the sustainable release control of nanocurcumin  in the thermogel system. These results showed potential application of the biomaterial in tissue regeneration.

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