scholarly journals Potentialities of bioinspired metal and metal oxide nanoparticles in biomedical sciences

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 24722-24746
Author(s):  
Kshitij RB Singh ◽  
Vanya Nayak ◽  
Jay Singh ◽  
Ajaya Kumar Singh ◽  
Ravindra Pratap Singh

Bioinspired metallic nanoparticles (BMN) have revolutionized the biomedical domain and are still developing rapidly. Hence, this review on BMN elaborates the properties, biosynthesis, biomedical applications, and its role in combating the SARS-CoV-2.

2022 ◽  
pp. 205-231
Author(s):  
Raj Kumar ◽  
Guruprasad Reddy Pulikanti ◽  
Konathala Ravi Shankar ◽  
Darsi Rambabu ◽  
Venkateswarulu Mangili ◽  
...  

Nanomaterials ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 766 ◽  
Author(s):  
Harsh Kumar ◽  
Kanchan Bhardwaj ◽  
Kamil Kuča ◽  
Anu Kalia ◽  
Eugenie Nepovimova ◽  
...  

Green synthesis has gained wide attention as a sustainable, reliable, and eco-friendly approach to the synthesis of a variety of nanomaterials, including hybrid materials, metal/metal oxide nanoparticles, and bioinspired materials. Plant flowers contain diverse secondary compounds, including pigments, volatile substances contributing to fragrance, and other phenolics that have a profound ethnobotanical relevance, particularly in relation to the curing of diseases by ‘Pushpa Ayurveda’ or floral therapy. These compounds can be utilized as potent reducing agents for the synthesis of a variety of metal/metal oxide nanoparticles (NPs), such as gold, silver, copper, zinc, iron, and cadmium. Phytochemicals from flowers can act both as reducing and stabilizing agents, besides having a role as precursor molecules for the formation of NPs. Furthermore, the synthesis is mostly performed at ambient room temperatures and is eco-friendly, as no toxic derivatives are formed. The NPs obtained exhibit unique and diverse properties, which can be harnessed for a variety of applications in different fields. This review reports the use of a variety of flower extracts for the green synthesis of several types of metallic nanoparticles and their applications. This review shows that flower extract was mainly used to design gold and silver nanoparticles, while other metals and metal oxides were less explored in relation to this synthesis. Flower-derived silver nanoparticles show good antibacterial, antioxidant, and insecticidal activities and can be used in different applications.


2020 ◽  
Vol 20 (6) ◽  
pp. 3303-3339 ◽  
Author(s):  
Saee Gharpure ◽  
Aman Akash ◽  
Balaprasad Ankamwar

The field of nanotechnology elaborates the synthesis, characterization as well as application of nanomaterials. Applications of nanoparticles in various fields have interested scientists since decades due to its unique properties. Combination of pharmacology with nanotechnology has helped in development of newer antimicrobial agents in order to control the ever increasing multidrug resistant micro-organisms. Properties of metal and metal oxide nanoparticles like silver, gold, titanium dioxide as well as magnesium oxide as antimicrobial agents are very well known. This review elaborates synthesis methods and antimicrobial mechanisms of various metal as well as metal oxide nanoparticles for better understanding in order to utilize their potentials in various biomedical applications.


2014 ◽  
Vol 11 (2) ◽  
pp. 139-149 ◽  
Author(s):  
Denisa Ficai ◽  
Ovidiu Oprea ◽  
Anton Ficai ◽  
Alina Holban

Materials ◽  
2021 ◽  
Vol 14 (23) ◽  
pp. 7287
Author(s):  
Tania Limongi

The current Special Issue entitled “Metal and Metal Oxide Nanoparticles: Design, Characterization, and Biomedical Applications” aims to present contributions from all scientists producing and/or applying metal and metal oxide nanoparticles in a diagnostic, therapeutic or theranostics context [...]


2016 ◽  
Vol 12 ◽  
pp. 1366-1371 ◽  
Author(s):  
Souad Kachbi-Khelfallah ◽  
Maelle Monteil ◽  
Margery Cortes-Clerget ◽  
Evelyne Migianu-Griffoni ◽  
Jean-Luc Pirat ◽  
...  

The use of nanotechnologies for biomedical applications took a real development during these last years. To allow an effective targeting for biomedical imaging applications, the adsorption of plasmatic proteins on the surface of nanoparticles must be prevented to reduce the hepatic capture and increase the plasmatic time life. In biologic media, metal oxide nanoparticles are not stable and must be coated by biocompatible organic ligands. The use of phosphonate ligands to modify the nanoparticle surface drew a lot of attention in the last years for the design of highly functional hybrid materials. Here, we report a methodology to synthesize bisphosphonates having functionalized PEG side chains with different lengths. The key step is a procedure developed in our laboratory to introduce the bisphosphonate from acyl chloride and tris(trimethylsilyl)phosphite in one step.


2020 ◽  
Vol 26 (45) ◽  
pp. 5844-5865
Author(s):  
Nabila Zafar ◽  
Ahmed Madni ◽  
Ayesha Khalid ◽  
Taous Khan ◽  
Rozina Kousar ◽  
...  

Background: Due to the rapid growth in life threatening diseases such as cancer, diabetes, chronic wound and HIV/AIDS along with rise of side effects of the current treatments, world is now focusing to utilize new treatment options. Currently, the development of green nanotechnology field seems as a potential alternate for diseases diagnosis and treatment by preparation of various sizes and shapes of nanomaterials. Objective: This review is to present the explored biological sources in synthesis of nanomaterials particularly metal and metal oxides nanoparticles and critical review of the applications of biosynthesized nanoparticles in pharmaceutical and biomedical fields. Methods: In this review, the various biological sources including bacteria, fungi, algae and plants used in synthesis of nanomaterials and mechanism involved in preparation are elaborated. In addition, biosynthesized nanomaterials applied as drug delivery system for anticancer, antibiotic, antidiabetic agent and functioned as potential diagnostic, antimicrobial, anticancer and wound healing candidates are comprehensively reviewed. Results: The synthesized metal and metal oxides from green protocol proved to have advantages such as being biocompatible, effective and cheap. Furthermore, the green synthesized metal and metal oxide nanoparticles showed to possess prominent physical, chemical and biological properties that can be efficiently utilized for pharmaceutical and biomedical applications. Conclusion: The information gathered in this review will provide a baseline for exploring more potential usage of green synthesized metal and metal oxide nanomaterials for various other applications. However, a concrete understanding of the safety of these nanomaterials is still needed to minimize the potential side effects.


Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 460
Author(s):  
Anteneh Marelign Beyene ◽  
Mohammad Moniruzzaman ◽  
Adhimoolam Karthikeyan ◽  
Taesun Min

In the past few decades, curcumin, a natural polyphenolic phytochemical, has been studied for treating a wide variety of diseases. It has shown promising results as a potential curative agent for a variety of diseases. However, its inherent limitations, such as poor aqueous solubility, poor absorbability, fast metabolic rate, and quick elimination from the body, have limited its application beyond preclinical studies. A huge number of studies have been made to address the issues of curcumin and to maximally utilize its potentials. Many review articles have tried to assess and summarize different nanocarriers, especially organic nanocarriers, for nanoformulations with curcumin. Nevertheless, few exclusive reviews on the progress in nanoformulation of curcumin with inorganic nanomaterials have been made. In this review, we present an exclusive summary of the progress in nanoformulation of curcumin with metal oxide nanoparticles. The beneficial feature of the metal oxide nanoparticles used in the curcumin nanoformulation, the different approaches followed in formulating curcumin with the metal oxides, and the corresponding results, protective effect of curcumin from different metal oxide caused toxicities, and concluding remarks are presented in the review.


2018 ◽  
pp. 459-486
Author(s):  
Yiik Siang Hii ◽  
Jaison jeevanandam ◽  
Yen San Chan ◽  
Michael K. Danquah

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