scholarly journals PEGylated ethyl cellulose micelles as a nanocarrier for drug delivery

RSC Advances ◽  
2021 ◽  
Vol 11 (49) ◽  
pp. 30532-30543
Author(s):  
Amarnath Singam ◽  
Naresh Killi ◽  
Pratikshkumar R. Patel ◽  
Rathna V. N. Gundloori

Ethyl cellulose was developed as an amphiphilic polymer by PEGylation and fabricated as nanomicelles for delivery of active molecules. This polymeric system can be used as next generation nano drug delivery system (nanoDDS) for cancer therapy.

2020 ◽  
Vol 8 (10) ◽  
pp. 2040-2047
Author(s):  
Yejin Zhu ◽  
Yongjian Guo ◽  
Mengdi Liu ◽  
Libin Wei ◽  
Xiaotang Wang

A novel AIE-active drug delivery system was developed for imaging-guided cancer therapy with improved efficacy.


Drug Delivery ◽  
2021 ◽  
Vol 29 (1) ◽  
pp. 138-148
Author(s):  
Xue Liu ◽  
Zhenfeng Wu ◽  
Chunjing Guo ◽  
Huimin Guo ◽  
Yanguo Su ◽  
...  

Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 345
Author(s):  
Ying Sun ◽  
Xiaoli Ma ◽  
Hao Hu

Marine biomass is a treasure trove of materials. Marine polysaccharides have the characteristics of biocompatibility, biodegradability, non-toxicity, low cost, and abundance. An enormous variety of polysaccharides can be extracted from marine organisms such as algae, crustaceans, and microorganisms. The most studied marine polysaccharides include chitin, chitosan, alginates, hyaluronic acid, fucoidan, carrageenan, agarose, and Ulva. Marine polysaccharides have a wide range of applications in the field of biomedical materials, such as drug delivery, tissue engineering, wound dressings, and sensors. The drug delivery system (DDS) can comprehensively control the distribution of drugs in the organism in space, time, and dosage, thereby increasing the utilization efficiency of drugs, reducing costs, and reducing toxic side effects. The nano-drug delivery system (NDDS), due to its small size, can function at the subcellular level in vivo. The marine polysaccharide-based DDS combines the advantages of polysaccharide materials and nanotechnology, and is suitable as a carrier for different pharmaceutical preparations. This review summarizes the advantages and drawbacks of using marine polysaccharides to construct the NDDS and describes the preparation methods and modification strategies of marine polysaccharide-based nanocarriers.


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