scholarly journals A novel coumarin-based colorimetric and fluorescent probe for detecting increasing concentrations of Hg2+in vitro and in vivo

RSC Advances ◽  
2021 ◽  
Vol 11 (38) ◽  
pp. 23597-23606
Author(s):  
Li Huang ◽  
Wenlong Sheng ◽  
Lizhen Wang ◽  
Xia Meng ◽  
Hongdong Duan ◽  
...  

Mercury has complex biological toxicity and can cause a variety of physiological diseases and even death, so it is of great importance to develop novel strategies for detecting trace mercury in environmental and biological samples.

RSC Advances ◽  
2015 ◽  
Vol 5 (104) ◽  
pp. 85957-85963 ◽  
Author(s):  
Peng Wang ◽  
Ke Wang ◽  
Dan Chen ◽  
Yibo Mao ◽  
Yueqing Gu

A novel NIR fluorescent probe (DCM-B2) based on dicyanomethylene-4H-pyran was synthesized for the detection of H2O2.


Talanta ◽  
2018 ◽  
Vol 185 ◽  
pp. 396-404 ◽  
Author(s):  
Jiao Gong ◽  
Yuan-heng Li ◽  
Chan-juan Zhang ◽  
Jian Huang ◽  
Qi Sun
Keyword(s):  

2020 ◽  
Vol 44 (28) ◽  
pp. 12107-12112 ◽  
Author(s):  
Yunyan Zhang ◽  
Xiuqi Kong ◽  
Yonghe Tang ◽  
Min Li ◽  
Yaguang Yin ◽  
...  

A novel ratiometric fluorescent probe, Hcy-CO, with long-wavelength emission was developed for visualizing CO in living cells and zebrafish.


The Analyst ◽  
2019 ◽  
Vol 144 (12) ◽  
pp. 3807-3816 ◽  
Author(s):  
Xiaojun He ◽  
Chenglin Wu ◽  
Yuna Qian ◽  
Yahui Li ◽  
Lilei Zhang ◽  
...  

Here reported an NBDT sensor could be effectively responsive to gallium and chromium for bio-imaging in vivo.


Author(s):  
Aiqing Feng ◽  
Yongmei Jia ◽  
Liping Huang ◽  
Lin Wang ◽  
Guohua Zhou ◽  
...  

Cancers ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 470 ◽  
Author(s):  
Surendra Punganuru ◽  
Hanumantha Madala ◽  
Viswanath Arutla ◽  
Kalkunte Srivenugopal

Human NAD(P)H quinone oxidoreductase-1 (hNQO1) is an important cancer-related biomarker, which shows significant overexpression in malignant cells. Developing an effective method for detecting NQO1 activity with high sensitivity and selectivity in tumors holds a great potential for cancer diagnosis, treatment, and management. In the present study, we report a new dicyanoisophorone (DCP) based fluorescent probe (NQ-DCP) capable of monitoring hNQO1 activity in vitro and in vivo in both ratiometric and turn-on model. NQ-DCP was prepared by conjugating dicyanoisophorone fluoroprobe with hNQO1 activatable quinone propionic acid (QPA), which remain non-fluorescent until activation by tumor-specific hNQO1. NQ-DCP featured a large Stokes shift (145 nm), excellent biocompatibility, cell permeability, and selectivity towards hNQO1 allowed to differentiate cancer cells from healthy cells. We have successfully employed NQ-DCP to monitor non-invasive endogenous hNQO1 activity in brain tumor cells in vitro and in xenografted tumors developed in nude mice.


2010 ◽  
Vol 1 (2) ◽  
pp. 617 ◽  
Author(s):  
Mário Augusto da Silva Martins ◽  
Dayana Gonçalves Ribeiro ◽  
Edson Aparecido Pereira dos Santos ◽  
Airton Abrahão Martin ◽  
Adriana Fontes ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document