Organocatalytic enantioselective Diels–Alder reaction between hydroxymaleimides and in situ generated nitrosoalkenes for direct preparation of chiral hemiketals with 1,2-oxazine skeleton

2021 ◽  
Author(s):  
Min Xiang ◽  
Chen-Yi Li ◽  
Jian Zhang ◽  
Ying Zou ◽  
Wen-Sheng Li ◽  
...  
Keyword(s):  
Alder Reaction ◽  
Diels Alder ◽  
Diels Alder Reaction ◽  
Direct Preparation

Organocatalytic Enantioselective IEDDA reaction between hydroxymaleimides and in situ generated nitrosoalkenes has been disclosed, a series of chiral hemiketals containing 5,6-dihydro-4H-l,2-oxazines and succinimide frameworks have been prepared.

Mechanochemical milling promoted solvent-free imino Diels–Alder reaction catalyzed by FeCl3: diastereoselective synthesis of cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines

RSC Advances ◽  
2014 ◽  
Vol 4 (67) ◽  
pp. 35635-35638 ◽  
Author(s):  
Ya-Jun Tan ◽  
Ze Zhang ◽  
Fang-Jian Wang ◽  
Hao-Hao Wu ◽  
Qing-Hai Li
Keyword(s):  
Ball Milling ◽  
Alder Reaction ◽  
Diels Alder ◽  
Solvent Free ◽  
Diastereoselective Synthesis ◽  
Diels Alder Reaction ◽  
Mechanochemical Milling

Cis-2,4-diphenyl-1,2,3,4-tetrahydroquinolines were diastereoselectively synthesized by FeCl3-promoted solvent-free Diels–Alder reaction of in situ generated imine with styrene under ball milling.

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