Azine- and Imine-linked Conjugated PolyHIPEs through Schiff-Base Condensation Reaction

2021 ◽  
Author(s):  
Sebastijan Kovacic ◽  
Tomaž Kotnik ◽  
Gregor Žerjav ◽  
Albin Pintar ◽  
Ema Žagar
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Condensation Reaction ◽  
Metal Free ◽  
New Type ◽  
Highly Porous ◽  
Concentrated Emulsion ◽  
Templating Technique ◽  
Type Of Transition

A new type of transition metal-free π-conjugated polyHIPEs is obtained by a Schiff-base condensation reaction coupled with a concentrated emulsion-based templating technique. The resulting highly porous azine- or imine-linked poly(arylene)...

scholarly journals Synthesis and Spectral Studies of 4,4′-(Hydrazine-1,2-diylidenedimethylylidene)-bis-(2- methoxyphenol) and Its Transition Metal Complexes with Promising Biological Activities

2020 ◽  
Vol 32 (7) ◽  
pp. 1768-1772
Author(s):  
Anita Rani ◽  
Manoj Kumar ◽  
Hardeep Singh Tuli ◽  
Zahoor Abbas ◽  
Vinit Prakash
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Schiff Base Ligand ◽  
Biological Activities ◽  
Condensation Reaction ◽  
Analytical Techniques ◽  
Spectral Studies

The study describes the synthesis, characterization and biological activity of a novel Schiff base ligand and its transition metal complexes. The Schiff base ligand was obtained by a condensation reaction between 4-hydroxy-3-methoxybenzaldehyde (p-vanillin) and hydrazine hydrate using ethanol as solvent. A new series of Ni(II) and Fe(III) complexes were also derived by reaction of prepared Schiff base ligand with NiCl2 and FeCl3. Both the ligand and its metal complexes were characterized by solubility, melting point and elemental analysis. These compounds were further identified by analytical techniques, FTIR, NMR and mass spectrometry. The ligand and its transition metal complexes were also subjected to in vitro biological activities i.e. antimicrobial, antiangiogenic and DNA photo cleavage. For antimicrobial activity compounds were tested against two strains of bacteria and two strains of fungi. Different concentrations of prepared compounds were treated with fertilized chicken eggs and plasmid DNA to find out antiangiogenic and DNA photocleavage activity, respectively.

Transition-metal-free and halogen-free controlled synthesis of poly(3-alkylthienylene vinylene) via the Horner–Wadsworth–Emmons condensation reaction

2018 ◽  
Vol 9 (15) ◽  
pp. 1996-2001 ◽  
Author(s):  
Eisuke Goto ◽  
Yuto Ochiai ◽  
Mitsuru Ueda ◽  
Tomoya Higashihara
Keyword(s):  
Transition Metal ◽  
Condensation Reaction ◽  
Controlled Synthesis ◽  
Controlled Polymerization ◽  
Metal Free ◽  
Halogen Free

Controlled polymerization without a transition metal or halogen.

760. A new type of transition metal–cyclopentadiene compound

1959 ◽  
Vol 0 (0) ◽  
pp. 3753-3767 ◽  
Author(s):  
M. L. H. Green ◽  
L. Pratt ◽  
G. Wilkinson
Keyword(s):  
Transition Metal ◽  
New Type ◽  
Type Of Transition

scholarly journals Synthesis and Characterization of Bioactive Acylpyrazolone Sulfanilamides and Their Transition Metal Complexes: Single Crystal Structure of 4-Benzoyl-3-methyl-1-phenyl-2-pyrazolin-5-one Sulfanilamide

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Omoruyi G. Idemudia ◽  
Alexander P. Sadimenko ◽  
Anthony J. Afolayan ◽  
Eric C. Hosten
Keyword(s):  
Crystal Structure ◽  
Schiff Base ◽  
Transition Metal ◽  
Metal Complexes ◽  
Single Crystal ◽  
Transition Metal Complexes ◽  
Antimicrobial Agents ◽  
Biological Activities ◽  
Condensation Reaction ◽  
Single Crystal Structure

Two Schiff base ligands Ampp-Sn1and Bmpp-Sn2, afforded by a condensation reaction between sulfanilamide and the respective acylpyrazolone carbonyl precursors, their Mn(II), Co(II), Ni(II), and Cu(II) complexes prepared by the reaction of ligands and corresponding metal salts in aqueous solutions, were synthesized and then characterized by both analytical and spectroscopic methods, in a view to developing new improved bioactive materials with novel properties. On the basis of elemental analysis, spectroscopic and TGA results, transition metal complexes, with octahedral geometry having two molecules of the bidentate keto-imine ligand each, have been proposed. The single crystal structure of Bmpp-Sn according to X-ray crystallography showed a keto-imine tautomer type of Schiff base, having three intramolecular bonds, one short N2⋯H2⋯O3 hydrogen bond of 1.90 Å and two long C13⋯H13⋯O2 and C32⋯H32⋯O3 hydrogen bonds of 2.48 Å. A moderate to low biological activities have been exhibited by synthesized compounds when compared with standard antimicrobial agents on screening the synthesized compounds againstStaphylococcus aureus,Bacillus pumilus,Proteus vulgaris, andAeromonas hydrophilafor antibacterial activity and against free radical 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) for antioxidant activity.

scholarly journals Template Synthesis of New Type of Macrocyclic Molecule Derived from Pyridine-2, 6-decarboxaldehyde and 1,2-bis(2-Aminoethoxy) Ethane

2011 ◽  
Vol 35 (1) ◽  
pp. 61-65 ◽  
Author(s):  
Md Mahbubul Alam
Keyword(s):  
Schiff Base ◽  
Template Synthesis ◽  
Metal Source ◽  
Metal Free ◽  
Esi Ms ◽  
Template Condensation ◽  
New Type ◽  
Academy Of Sciences

The cyclic (2+2) template condensation of pyridine-2,6-dicarboxaldehyde with 1,2-bis(2- aminoethoxy) ethane using Pb(SCN)2 as the metal source gave dinuclear lead (II) complex, Pb2L1(SCN)4 (1), where L1 is tetra-Schiff-base macrocycle. Treatment of 1 with NaBH4 in methanol gave a metal-free reduced macrocycle L2 which has been characterized by 1HNMR and ESI-MS spectroscopy.DOI: http://dx.doi.org/10.3329/jbas.v35i1.7971Journal of Bangladesh Academy of Sciences, Vol.35, No.1, 61-65, 2011

State-of-the-art catechol porphyrin COF catalyst for chemical fixation of carbon dioxide via cyclic carbonates and oxazolidinones

2016 ◽  
Vol 6 (15) ◽  
pp. 6152-6158 ◽  
Author(s):  
Vitthal Saptal ◽  
Digambar Balaji Shinde ◽  
Rahul Banerjee ◽  
Bhalchandra M. Bhanage
Keyword(s):  
Carbon Dioxide ◽  
Transition Metal ◽  
State Of The Art ◽  
Value Added ◽  
Chemical Fixation ◽  
Cyclic Carbonates ◽  
Metal Free ◽  
Highly Porous ◽  
Fixation Of Carbon Dioxide

A highly porous, crystalline catechol porphyrin COF was synthesized and applied as an organocatalyst for the fixation of carbon dioxide to synthesize value-added chemicals such as cyclic carbonates and oxazolidinones under solvent and transition-metal-free conditions.

scholarly journals A Practical and Modular Construction of C(sp3)-rich Alkyl Boron Compounds

2020 ◽  
Author(s):  
Yangyang Yang ◽  
Jet Tsien ◽  
Ayala Ben David ◽  
Jonathan Hughes ◽  
Rohan Merchant ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Functional Group ◽  
Cross Coupling ◽  
Boronic Acids ◽  
Modular Construction ◽  
Boron Compounds ◽  
Metal Free ◽  
Coupling Approach ◽  
New Type ◽  
Type Of Transition

Alkyl boronic acids and esters play an important role in the synthesis of C(sp<sup>3</sup>) rich medicines, agrochemicals, and other materials. This work describes a new type of transition-metal free mediated transformation to enable the construction of C(sp<sup>3</sup>)-rich, and sterically hindered alkyl boron reagents in a practical and modular manner. The broad generality and functional group tolerance of this method is extensively examined through a variety of substrates, including synthesis and late-stage functionalization of scaffolds relevant to medicinal chemistry. The strategic significance of this approach, with alkyl boronic acid as a linchpin, is demonstrated through various downstream functionalizations of the alkyl boron compounds. This two-step concurrent cross-coupling approach, resembling formal and flexible alkyl-alkyl couplings, provides a general entry to previously synthetically challenging high Fsp<sup>3</sup>-containing drug-like scaffolds.

scholarly journals A Practical and Modular Construction of C(sp3)-rich Alkyl Boron Compounds

2020 ◽  
Author(s):  
Yangyang Yang ◽  
Jet Tsien ◽  
Ayala Ben David ◽  
Jonathan Hughes ◽  
Rohan Merchant ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Functional Group ◽  
Cross Coupling ◽  
Boronic Acids ◽  
Modular Construction ◽  
Boron Compounds ◽  
Metal Free ◽  
Coupling Approach ◽  
New Type ◽  
Type Of Transition

Alkyl boronic acids and esters play an important role in the synthesis of C(sp<sup>3</sup>) rich medicines, agrochemicals, and other materials. This work describes a new type of transition-metal free mediated transformation to enable the construction of C(sp<sup>3</sup>)-rich, and sterically hindered alkyl boron reagents in a practical and modular manner. The broad generality and functional group tolerance of this method is extensively examined through a variety of substrates, including synthesis and late-stage functionalization of scaffolds relevant to medicinal chemistry. The strategic significance of this approach, with alkyl boronic acid as a linchpin, is demonstrated through various downstream functionalizations of the alkyl boron compounds. This two-step concurrent cross-coupling approach, resembling formal and flexible alkyl-alkyl couplings, provides a general entry to previously synthetically challenging high Fsp<sup>3</sup>-containing drug-like scaffolds.

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