Ultrafast, green and recyclable photoRDRP in ionic liquid towards multi-stimuli responsive amphiphilic copolymers

2021 ◽  
Author(s):  
Sk Arif Mohammad ◽  
Devendra Kumar ◽  
Md Mehboob Alam ◽  
Sanjib Banerjee

A simple and inexpensive method on ultrafast and recyclable photoRDRP (in the absence of any conventional pho-toinitiators or dye sensitizers) in ionic liquid is developed, yielding low dispersity poly(glycidyl methacrylate)...

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2890
Author(s):  
Adrian Domiński ◽  
Tomasz Konieczny ◽  
Khadar Duale ◽  
Monika Krawczyk ◽  
Gabriela Pastuch-Gawołek ◽  
...  

Nanoparticles based on amphiphilic copolymers with tunable physicochemical properties can be used to encapsulate delicate pharmaceutics while at the same time improving their solubility, stability, pharmacokinetic properties, reducing immune surveillance, or achieving tumor-targeting ability. Those nanocarriers based on biodegradable aliphatic polycarbonates are a particularly promising platform for drug delivery due to flexibility in the design and synthesis of appropriate monomers and copolymers. Current studies in this field focus on the design and the synthesis of new effective carriers of hydrophobic drugs and their release in a controlled manner by exogenous or endogenous factors in tumor-specific regions. Reactive groups present in aliphatic carbonate copolymers, undergo a reaction under the action of a stimulus: e.g., acidic hydrolysis, oxidation, reduction, etc. leading to changes in the morphology of nanoparticles. This allows the release of the drug in a highly controlled manner and induces a desired therapeutic outcome without damaging healthy tissues. The presented review summarizes the current advances in chemistry and methods for designing stimuli-responsive nanocarriers based on aliphatic polycarbonates for controlled drug delivery.


2020 ◽  
Vol 30 (50) ◽  
pp. 2005522
Author(s):  
Jiecheng Cui ◽  
Yi Li ◽  
Dong Chen ◽  
Tian‐Guang Zhan ◽  
Kang‐Da Zhang

2020 ◽  
Vol 8 (35) ◽  
pp. 7994-8001 ◽  
Author(s):  
Beibei Lu ◽  
Gaoxin Zhou ◽  
Fan Xiao ◽  
Qianjun He ◽  
Jiaheng Zhang

A novel poly(ionic liquid) (PIL)-based block copolymer, which can self-assemble into spherical nanoparticles, high drug loading content, and good ability to inhibit tumors. Therefore, this copolymer shows great potential for drug delivery. 


The Analyst ◽  
2019 ◽  
Vol 144 (21) ◽  
pp. 6415-6421 ◽  
Author(s):  
Datong Wu ◽  
Fei Pan ◽  
Gao-Chao Fan ◽  
Ziming Zhu ◽  
Li Gao ◽  
...  

An electroactive chiral rotaxane, consisting of a polymeric chiral ionic liquid as the flexible axle and 18-crown-6 as the wheel, is synthesized for efficient enantiorecognition of amino acids.


2018 ◽  
Vol 20 (18) ◽  
pp. 4236-4244 ◽  
Author(s):  
Xiaoyan Pei ◽  
Dazhen Xiong ◽  
Yuanchao Pei ◽  
Huiyong Wang ◽  
Jianji Wang

Stimuli-responsive ionic liquid microemulsions can be reversibly switched from W/O monophase to oil–water phase separation upon alternate bubbling and removal of CO2.


2014 ◽  
Vol 5 (10) ◽  
pp. 3389 ◽  
Author(s):  
Qing-Lan Li ◽  
Lizhi Wang ◽  
Xi-Long Qiu ◽  
Yu-Long Sun ◽  
Pei-Xi Wang ◽  
...  

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