scholarly journals Thermoresponsive Properties of Polyacrylamides in Physiological Solutions

2021 ◽  
Author(s):  
Kristýna Kolouchová ◽  
Volodymyr Lobaz ◽  
Hynek Benes ◽  
Victor De la Rosa ◽  
David Babuka ◽  
...  
Keyword(s):  
Phase Separation ◽  
Cloud Point ◽  
Lower Critical Solution Temperature ◽  
Polymer Solutions ◽  
Solution Temperature ◽  
Critical Solution Temperature ◽  
Point Temperature ◽  
Cloud Point Temperature ◽  
Reversible Phase

Polymer solutions with a lower critical solution temperature (LCST) undergo reversible phase separation when heated above their cloud point temperature (TCP or CPT). As such, they have been proposed for...

A polyelectrolyte-containing copolymer with a gas-switchable lower critical solution temperature-type phase transition

2019 ◽  
Vol 10 (2) ◽  
pp. 260-266 ◽  
Author(s):  
Jin-Jin Li ◽  
Yin-Ning Zhou ◽  
Zheng-Hong Luo ◽  
Shiping Zhu
Keyword(s):  
Phase Transition ◽  
Cloud Point ◽  
Lower Critical Solution Temperature ◽  
Solution Temperature ◽  
Critical Solution Temperature ◽  
Type Phase

A polyelectrolyte-containing copolymer with a CO2/N2-switchable cloud point, resulting from the gas-induced alternation of hydrophilicity, was prepared.

Measurement of cloud point temperature in polymer solutions

2013 ◽  
Vol 84 (7) ◽  
pp. 075118 ◽  
Author(s):  
G. A. Mannella ◽  
V. La Carrubba ◽  
V. Brucato
Keyword(s):  
Cloud Point ◽  
Polymer Solutions ◽  
Point Temperature ◽  
Cloud Point Temperature

Cloud-point temperature and liquid–liquid phase separation of supersaturated lysozyme solution

2004 ◽  
Vol 109 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Jie Lu ◽  
Keith Carpenter ◽  
Rui-Jiang Li ◽  
Xiu-Juan Wang ◽  
Chi-Bun Ching
Keyword(s):  
Phase Separation ◽  
Liquid Phase ◽  
Cloud Point ◽  
Liquid Phase Separation ◽  
Point Temperature ◽  
Cloud Point Temperature ◽  
Liquid Liquid Phase Separation

THERMOSENSITIVE NANOPARTICLES CONJUGATING WITH CD34 ANTIBODY AND ITS SOLUTION PEROPERTIES

2006 ◽  
Vol 18 (05) ◽  
pp. 222-228 ◽  
Author(s):  
CHUN-TE TAO ◽  
TAI-HORNG YOUNG
Keyword(s):  
Controlled Release ◽  
Cloud Point ◽  
Lower Critical Solution Temperature ◽  
Homogeneous Solution ◽  
The Body ◽  
Solution Temperature ◽  
Temperature Sensitive ◽  
Critical Solution Temperature ◽  
Human Cd34 ◽  
Collapse Temperature

Poly N-isopropylacrylamide (PNIPAAm) is a well-known temperature-sensitive polymer. When the temperature is higher than the lower critical solution temperature (LCST), PNIPAAm aquous solution is cloudy (phase separation occurred). In contrast, when the temperature is lower than the LCST, PNIPAAm is soluble in water (a homogeneous solution). The lower critical solution temperature (LCST) in aqueous solution of PNIPAAm was about 32~33°C. We prepared nano-scaled PNIPAAm particles containing carboxylic group on their surfaces by introducing acrylic acid monomer. The carboxylic groups were applied to conjugate with the amino group of the CD34 antibody. This immuno-conjugate can be applied on targeting the human CD34 positive cells, peripheral blood progenitor cells included, for cell purification and drug controlled release. In order to the active responding of controlled release of the conjugate in the body influenced by temperature, we hope to estimate the shifting of the gel-collapse temperature or cloud point of the immuno-conjugates by dynamic light scattering (DLS) and UV absorption. The results show that the gel-collapse temperature of the nano-particle was not significantly affected by the content of AA between 1.5~5 mol%. However, cloud point of the solution was elevated by the conjugation of CD34 antibody to 37°C. When CD34-conjugated particle was subsequently incorporated with recombinant FLT3-ligand, which is a smaller molecule compare to CD34 antibody, cloud point of the solution was not affected.

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