Europium(iii)-containing nanohydrogels for cellular imaging and drug delivery applications

2021 ◽  
Author(s):  
Yicheng Wang ◽  
Yuxin Wang ◽  
Yaqin Hu ◽  
Wen Jing Yang ◽  
Lianhui Wang

By employing the excellent luminescence of Eu(iii) complexes and the versatility of nanohydrogels, Eu(iii)-containing nanohydrogels were prepared as a potential theranostic nanoplatform for cancer therapy.

RSC Advances ◽  
2015 ◽  
Vol 5 (105) ◽  
pp. 86754-86762 ◽  
Author(s):  
Jerina Majeed ◽  
K. C. Barick ◽  
Neena G. Shetake ◽  
B. N. Pandey ◽  
P. A. Hassan ◽  
...  

Development of water-dispersible polyphosphate-grafted Fe3O4 nanomagnets for hyperthermia and drug delivery applications.


2019 ◽  
Vol 51 (1) ◽  
pp. 91-104 ◽  
Author(s):  
Seyyed Mojtaba Mousavi ◽  
Sadaf Soroshnia ◽  
Seyyed Alireza Hashemi ◽  
Aziz Babapoor ◽  
Younes Ghasemi ◽  
...  

MedChemComm ◽  
2017 ◽  
Vol 8 (9) ◽  
pp. 1797-1805 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Subramanian Bharathiraja ◽  
Panchanathan Manivasagan ◽  
Kang Dae Lee ◽  
Junghwan Oh

Herein, we propose a “host–guest” complexation-based mesoporous silica drug carrier, MSNs@Mela@TTM, for pH-responsive drug delivery applications in cancer therapy.


2015 ◽  
Vol 3 (37) ◽  
pp. 7401-7407 ◽  
Author(s):  
Haibo Wang ◽  
Gongyan Liu ◽  
Shihua Dong ◽  
Junjie Xiong ◽  
Zongliang Du ◽  
...  

A multifunctional drug delivery system with AIE character was designed and constructed for simultaneous cellular imaging and pH-triggered drug release.


Author(s):  
Panagiota G. Fragouli ◽  
Dimitra Stavroulaki ◽  
Panagiotis Christakopoulos ◽  
Varvara Athanasiou ◽  
Maria Kasimati ◽  
...  

2018 ◽  
Vol 5 (3) ◽  
pp. 175-187 ◽  
Author(s):  
O. V. Gorovtsova ◽  
T. L. Ushakova ◽  
V. G. Polyakov

Retinoblastoma is one of highly curable diseases; today the total 5-year survival rate in patients with retinoblastoma exceeds 95%. The article summarizes the current world experience on treatment of patients with intraocular retinoblastoma. The treating skills of intraocular malignant tumor in children are a balance between the patient’s life and the preservation of an eye and its visual functions. The complex and challenging task is the treatment of common intraocular retinoblastoma groups «C», «D», «E» when the large size or localization of the tumor does not allow performing the local (focal) destruction of the tumor. As a rule, in such cases neoadjuvant chemotherapy (CT) is performed at the first stage in order to reduce the size of the tumor for further focal therapy. However, the analysed data on the effectiveness of neoadjuvant CT in combination with focal or radiotherapy demonstrated the limited possibilities of the proposed therapy. Local drug delivery in cancer therapy became a real breakthrough in the organ-preserving treatment of children with large intraocular retinoblastoma. The most widely used current methods of local drug delivery are intravitreal (IVitC) and selective intra-arterial chemotherapy (SIAC) as monotherapy or in combination with neoadjuvant CT and focal therapy which significantly increased the percentage of preserved eyes without radiotherapy administration or damage to the patient survival. The review discusses the different IVitC and SIAC techniques, chemotherapy schemes, dosages of chemotherapy, immediate and long-term complications of treatment.


Author(s):  
Azadi A. ◽  
Khazaei M. ◽  
Ashrafi H.

Cancer, an uncontrollable growth of cells, is among the leading causes of mortality and morbidity throughout the world. Malignant neoplasms are difficult to treat diseases because of their single in kind characteristics such as tissue invasion, metastasis, evading reticuloendothelial system (RES) and so forth. In recent decade polymeric nanoparticulate systems has gained special attention in drug delivery and targeting among all biocompatible nanoforms. Among these systems, chitosan-based hydrogel nanoparticles have been wildly utilized for drug delivery purposes. The usage of chitosan nanogels in cancer therapy significantly improved in recent years. The various cancers were the target of chitosan nanogels. Also, modification of other delivery systems with chitosan were much reported. The aim of this study is the review and update of the recent studies on chitosan nanogels applications in cancer therapy by focus on cancer based classification.


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