Fabrication of reversible pH-responsive aggregation-induced emission luminogens assisted by a block copolymer via a dynamic covalent bond

2021 ◽  
Author(s):  
Meiyao Wang ◽  
Lili Xu ◽  
Min Lin ◽  
Zhibo Li ◽  
Jing Sun
Keyword(s):  
Block Copolymer ◽  
Covalent Bond ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Aggregation Induced Emission

Aggregated induced emission (AIE) molecules with stimuli-responsive properties have attracted increasing attention for many applications.

A stimuli responsive two component supramolecular hydrogelator with aggregation-induced emission properties

Soft Matter ◽  
2019 ◽  
Vol 15 (36) ◽  
pp. 7117-7121 ◽  
Author(s):  
Dennis Aschmann ◽  
Steffen Riebe ◽  
Thorben Neumann ◽  
Dennis Killa ◽  
Jan-Erik Ostwaldt ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Aggregation Induced Emission ◽  
Emission Properties ◽  
Two Component

A dual pH-responsive two component hydrogelator with aggregation-induced emission properties is described. The orchestration of supramolecular guadiniumcarbonylpyrrole dimerisation and the recognition of carboxylic acid is reason for the gelation.

Double stimuli-responsive polysaccharide block copolymers as green macrosurfactants for near-infrared photodynamic therapy

Soft Matter ◽  
2019 ◽  
Vol 15 (6) ◽  
pp. 1423-1434 ◽  
Author(s):  
Benjamin B. Breitenbach ◽  
Elena Steiert ◽  
Matthias Konhäuser ◽  
Lea-Marie Vogt ◽  
Yujen Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Block Copolymers ◽  
Near Infrared ◽  
Aqueous Media ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Water Dispersible

The NIR absorbing photosensitizer phthalocyanine zinc (PC(Zn)) was stabilized in aqueous media as water-dispersible nanoparticles with a reduction- and pH-responsive full polysaccharide block copolymer.

scholarly journals Stimuli-Responsive Lyotropic Liquid Crystalline Nanosystems with Incorporated Poly(2-Dimethylamino Ethyl Methacrylate)-b-Poly(Lauryl Methacrylate) Amphiphilic Block Copolymer

Polymers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1400 ◽  
Author(s):  
Maria Chountoulesi ◽  
Natassa Pippa ◽  
Varvara Chrysostomou ◽  
Stergios Pispas ◽  
Evangelia D. Chrysina ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Liquid Crystalline ◽  
Polymer Concentration ◽  
Morphological Characteristics ◽  
Amphiphilic Block Copolymer ◽  
Poloxamer 407 ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Ethyl Methacrylate ◽  
Liquid Crystalline Nanoparticles

There is an emerging need to evolve the conventional lyotropic liquid crystalline nanoparticles to advanced stimuli-responsive, therapeutic nanosystems with upgraded functionality. Towards this effort, typically used stabilizers, such as Pluronics®, can be combined or replaced by smart, stimuli-responsive block copolymers. The aim of this study is to incorporate the stimuli-responsive amphiphilic block copolymer poly(2-(dimethylamino)ethyl methacrylate)-b-poly(lauryl methacrylate) (PDMAEMA-b-PLMA) as a stabilizer in lipidic liquid crystalline nanoparticles, in order to provide steric stabilization and simultaneous stimuli-responsiveness. The physicochemical and morphological characteristics of the prepared nanosystems were investigated by light scattering techniques, cryogenic-transmission electron microscopy (cryo-TEM), X-ray diffraction (XRD) and fluorescence spectroscopy. The PDMAEMA-b-PLMA, either individually or combined with Poloxamer 407, exhibited different modes of stabilization depending on the lipid used. Due to the protonation ability of PDMAEMA blocks in acidic pH, the nanoparticles exhibited high positive charge, as well as pH-responsive charge conversion, which can be exploited towards pharmaceutical applications. The ionic strength, temperature and serum proteins influenced the physicochemical behavior of the nanoparticles, while the polymer concentration differentiated their morphology; their micropolarity and microfluidity were also evaluated. The proposed liquid crystalline nanosystems can be considered as novel and attractive pH-responsive drug and gene delivery nanocarriers due to their polycationic content.

Core-crosslinked, temperature- and pH-responsive micelles: design, physicochemical characterization, and gene delivery application

Nanoscale ◽  
2021 ◽  
Author(s):  
Katharina Leer ◽  
Gizem Cinar ◽  
Jana I. Solomun ◽  
Liam Martin ◽  
Ivo Nischang ◽  
...  
Keyword(s):  
Block Copolymer ◽  
Gene Delivery ◽  
Genetic Material ◽  
Physicochemical Characterization ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Efficient Delivery ◽  
Block Copolymer Micelles ◽  
Copolymer Micelles

Stimuli-responsive block copolymer micelles can provide tailored properties for the efficient delivery of genetic material.

Novel pH-Responsive Triply Hydrophilic Block Copolymer with Reversible Micellization Property

2011 ◽  
Vol 181-182 ◽  
pp. 88-91 ◽  
Author(s):  
Xin De Tang ◽  
Ye Chen ◽  
Fa Qi Yu ◽  
Mei Shan Pei
Keyword(s):  
Drug Delivery ◽  
Ionic Strength ◽  
Block Copolymer ◽  
Solvent Polarity ◽  
Amphiphilic Polymers ◽  
Water Soluble ◽  
Stimuli Responsive ◽  
Ph Responsive ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Stimuli-responsive water-soluble and amphiphilic polymers have attracted much attention because their micelles can be produced or destroyed by changing the temperatute, pH, ionic strength, and solvent polarity. In this work, a triply hydrophilic block copolymer of poly (ethylene glycol) and poly (methacrylic acid-co-dimethylamine ethyl methacrylate) [PEO-P(MAA-co-DMAEMA)] was synthesized and characterized. The copolymer system is believed to have the potential for drug delivery applications due to the biocompatibility of MAA and DMAEMA.

Aggregation-induced emission polymer nanoparticles with pH-responsive fluorescence

2016 ◽  
Vol 7 (34) ◽  
pp. 5386-5395 ◽  
Author(s):  
Yuming Zhao ◽  
Wen Zhu ◽  
Lixia Ren ◽  
Ke Zhang
Keyword(s):  
Block Copolymer ◽  
Efficient Method ◽  
Self Assembly ◽  
Polymer Nanoparticles ◽  
Amphiphilic Block Copolymer ◽  
Ph Responsive ◽  
Aggregation Induced Emission ◽  
Post Functionalization

A convenient and efficient method was developed to prepare stable polymer nanoparticles with varied morphology and pH-responsive AIE properties, based on the amphiphilic block copolymer self-assembly, crosslinking, and post-functionalization techniques.

Soft stimuli-responsive grippers and machines with high load-to-weight ratios

2019 ◽  
Vol 6 (1) ◽  
pp. 160-168 ◽  
Author(s):  
Yajuan Sun ◽  
Linfeng Chen ◽  
Yan Jiang ◽  
Xuan Zhang ◽  
Xiukai Yao ◽  
...  
Keyword(s):  
General Class ◽  
High Load ◽  
Stimuli Responsive ◽  
Ph Responsive

A general class of stimuli-responsive grippers and actuators (e.g., temperature- and pH-responsive) with surprisingly high gripping strengths is introduced.

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