Copper(ii) triflate catalyzed three-component reaction for the synthesis of 2,3-diarylquinoline derivatives using aryl amines, aryl aldehydes and styrene oxides

2021 ◽  
Vol 19 (14) ◽  
pp. 3255-3262
Author(s):  
Saghir Ali ◽  
Abu T. Khan
Keyword(s):  
Aryl Aldehydes ◽  
Three Component Reaction ◽  
Aryl Amines

An efficient and expedient synthetic protocol is reported for the synthesis of 2,3-diarylquinoline derivatives from readily available aryl amines, aryl aldehydes and styrene oxides using 10 mol% copper(ii) triflate by employing three-component reaction.

Synthesis of 3-[(acetylamino)(aryl)methyl]-4-Hydroxycoumarins

2007 ◽  
Vol 2007 (9) ◽  
pp. 535-537 ◽  
Author(s):  
Mohammad Anary-Abbasinejad ◽  
Hossein Anaraki-Ardakani ◽  
Azimeh Saidipoor ◽  
Mahmood Shojaee
Keyword(s):  
Chlorosulfonic Acid ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Three Component Reaction ◽  
Aryl Methyl

One-pot, three-component reaction between aryl aldehydes, 4-hydroxycoumarin, and acetonitrile in the presence of chlorosulfonic acid affords 3-[(acetylamino)(aryl)methyl]-4-hydroxycoumarins in excellent yields.

PTSA-Catalyzed One Pot Domino Synthesis of Dihydropyrido[2,3-d]pyrimidine Derivatives and their Antimicrobial Activity

2021 ◽  
Vol 6 (3) ◽  
pp. 222-227
Author(s):  
Krishna A. Bhensdadia ◽  
Prakash L. Kalavadiya ◽  
Nilam H. Lalavani ◽  
Shipra H. Baluja
Keyword(s):  
Antimicrobial Activity ◽  
Spectral Analysis ◽  
Pyrimidine Derivatives ◽  
One Pot ◽  
In Vitro Antimicrobial Activity ◽  
Aryl Aldehydes ◽  
Three Component Reaction ◽  
The One

A novel series of dihydropyrido[2,3-d]pyrimidine derivatives were synthesized by multicomponent domino cyclization via the one-pot three component reaction of 6-amino uracil, substituted aryl aldehydes and N-methyl-1-(methylthio)-2-nitroethenamine in the presence of PTSA 10 mol% as a catalyst. The structures of these synthesized compounds were characterized by spectral analysis. Further the synthesized compounds screened for in vitro antimicrobial activity. Among all the compounds, compound 4b containing flouro substitution exhibited good inhibition against the tested species.

Three-component reaction of Cyclohexyl Isocyanide, Barbituric Acid and Aryl Aldehydes; Synthesis of N-cyclohexyl-N-[aryl-(2,4,6-trioxohexahydropyrimidin-5-yl)methyl]formamides

2007 ◽  
Vol 2007 (10) ◽  
pp. 594-597 ◽  
Author(s):  
Mohammad Anary-Abbasinejad ◽  
Maryam Kamali-Gharamaleki ◽  
Alireza Hassanabadi
Keyword(s):  
Barbituric Acid ◽  
Aryl Aldehydes ◽  
Three Component Reaction

Three-component reaction of cyclohexyl isocyanide, barbituric acid and different aldehydes, in a mixture of water: acetonitrile (1:1) as solvent, produces the corresponding N-cyclohexyl- N-[aryl-(2,4,6-trioxohexahydropyrimidin-5-yl)methyl]formamides in excellent yields.

Bifunctional organocatalysts for the conversion of CO2, epoxides and aryl amines to 3-aryl-2-oxazolidinones

2019 ◽  
Vol 17 (14) ◽  
pp. 3497-3506 ◽  
Author(s):  
Ya-Fei Xie ◽  
Cheng Guo ◽  
Lei Shi ◽  
Bang-Hua Peng ◽  
Ning Liu
Keyword(s):  
Three Component Reaction ◽  
Aryl Amines

A route to synthesize 3-aryl-2-oxazolidinones is developed, which is achieved through a three component reaction between CO2, aryl amines, and epoxides with a binary organocatalytic system composed of organocatalysts and DBU (1,8-diazabicyclo[5.4.0]undec-7-ene).

Hexyltriphenylphosphonium Bromide as an Absolutely Chemoselective Ionic Liquid Catalyst in the Three‐Component Reaction of Aryl Aldehydes, Acetophenones and Malononitrile

2019 ◽  
Vol 4 (20) ◽  
pp. 6190-6193
Author(s):  
Kiumars Bahrami ◽  
Mohammad M. Khodaei ◽  
Nasim Batooie ◽  
Nouraddin Hosseinzadeh ◽  
Alireza Foroumadi
Keyword(s):  
Ionic Liquid ◽  
Aryl Aldehydes ◽  
Three Component Reaction

Three-Component Reaction of Aldose Sugars, Aryl Amines, and 1,3-Diones:  A Novel Synthesis of Annulated Pyrroles

2008 ◽  
Vol 73 (8) ◽  
pp. 3252-3254 ◽  
Author(s):  
Jhillu S. Yadav ◽  
Basi V. Subba Reddy ◽  
Mende Srinivas ◽  
Chitteti Divyavani ◽  
Shaik Jeelani Basha ◽  
...  
Keyword(s):  
Novel Synthesis ◽  
Three Component Reaction ◽  
Aryl Amines

Metal-free synthesis of quinoline-2,4-dicarboxylate derivatives using aryl amines and acetylenedicarboxylates through pseudo three-component reaction

2021 ◽  
Author(s):  
Saghir Ali ◽  
Abu Taleb Khan
Keyword(s):  
Molecular Iodine ◽  
One Pot ◽  
Metal Free ◽  
Three Component Reaction ◽  
Aryl Amines

An efficient, useful and one-pot protocol for the synthesis of quinoline-2,4-dicarboxylate scaffolds is accomplished from aryl amines and dimethyl/diethyl acetylenedicarboxylates using 20 mol% molecular iodine as a catalyst in acetonitrile...

scholarly journals Efficient, One-Pot Synthesis of Tetrahydrobenzo[a]xanthen-11-ones and Dibenzo[a,j]xanthenes Using Trichloroacetic Acid as a Solid Heterogeneous Catalyst Under Solvent-Free Conditions

2011 ◽  
Vol 8 (4) ◽  
pp. 1895-1899 ◽  
Author(s):  
Zahed Karimi Jaber ◽  
S. Zoleykha Abbasi ◽  
Baharak Pooladian ◽  
Marziyeh Jokar
Keyword(s):  
Heterogeneous Catalyst ◽  
Efficient Method ◽  
Trichloroacetic Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Aryl Aldehydes ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
Free Media

A simple and efficient method have been described for the synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]xanthen-11-one derivatives employing a one-pot, three-component reaction of aryl aldehydes, 2-naphthol and dimedone in the presence of trichloroacetic acid under solvent-free conditions. Also the condensation of 2-naphthol with alkyl or aryl aldehydes in the presence of trichloroacetic acid under solvent-free media to afford the corresponding 14-aryl or alkyl -14H-dibenzo [a.j]xanthenes in excellent yields and short reaction times is described.

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