Self-driving dynamic plasmonic colors based on needle steering for simultaneous control of transition direction and time on metallic nanogroove metasurfaces

Nanoscale ◽  
2021 ◽  
Author(s):  
Xiaoping He ◽  
Guozhou Li ◽  
Dong Wu
Keyword(s):  
Dynamic Control ◽  
Great Promise ◽  
Driving Dynamic ◽  
Needle Steering ◽  
Color Display ◽  
Simultaneous Control ◽  
Wide Range

Dynamically tunable plasmonic colors hold great promise for a wide range of applications including color display, colorimetric sensning, and information encryption. However, dynamic control speed of plasmonic colors is still...

Phytochemical evaluation of leaf extracts of Naringi crenulata (roxb.) Nicolson

2016 ◽  
Vol 5 (11) ◽  
pp. 5110
Author(s):  
Sartaj Ahmad Allayie ◽  
Mushtaq Ahmed Parray* ◽  
Bilal Ahmad Bhat ◽  
S. Hemalatha
Keyword(s):  
Quantitative Analysis ◽  
Solvent System ◽  
Great Promise ◽  
Phytochemical Analysis ◽  
Bioactive Constituents ◽  
Leaf Extracts ◽  
Traditional Medicines ◽  
The People ◽  
Wide Range ◽  
Rf Values

The use of traditional medicines holds a great promise as an easily available source as effective medicinal agents to cure a wide range of ailments among the people particularly in tropical developing countries like India. The present study investigates the qualitative and quantitative analysis of the major bioactive constituents of N. crenulata leaf extracts. The extractive values of aqueous, acetone and chloroform extracts were found to be 11.34, 4.24 and 6.06 respectively. Qualitative phytochemical analysis of these three solvent extracts confirm the presence of Alkaloids, Saponins, Flavonoids and Phenolic compounds in all the three extracts; however, these phytochemicals were more significant in aqueous extract. Quantitative analysis was carried out using TLC method by different solvent system. Amongst various solvent systems, Butanol: acetic acid: water (9: 0.9: 0.1 v/v/v) shows maximum resolution and number of spots produced at long UV (365 nm) and under iodine vapours. The TLC chromatograms constituted different coloured phytochemical compounds with different Rf values. It can be conveniently used to evaluate the quality of different area samples. This indicates that the leaves can be useful for treating different diseases because the therapeutic activity of a plant is due to the presence of particular class of compounds and thus can serve as potential sources of useful drugs in future.

scholarly journals Wide range continuously tunable and fast thermal switching based on compressible graphene composite foams

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Tingting Du ◽  
Zixin Xiong ◽  
Luis Delgado ◽  
Weizhi Liao ◽  
Joseph Peoples ◽  
...  
Keyword(s):  
Thermal Management ◽  
Dynamic Control ◽  
Operating Conditions ◽  
Dynamic Thermal Management ◽  
Graphene Composite ◽  
Continuous Tuning ◽  
Composite Foams ◽  
Wide Range ◽  
Thermal Switches ◽  
Thermal Switching

AbstractThermal switches have gained intense interest recently for enabling dynamic thermal management of electronic devices and batteries that need to function at dramatically varied ambient or operating conditions. However, current approaches have limitations such as the lack of continuous tunability, low switching ratio, low speed, and not being scalable. Here, a continuously tunable, wide-range, and fast thermal switching approach is proposed and demonstrated using compressible graphene composite foams. Large (~8x) continuous tuning of the thermal resistance is achieved from the uncompressed to the fully compressed state. Environmental chamber experiments show that our variable thermal resistor can precisely stabilize the operating temperature of a heat generating device while the ambient temperature varies continuously by ~10 °C or the heat generation rate varies by a factor of 2.7. This thermal device is promising for dynamic control of operating temperatures in battery thermal management, space conditioning, vehicle thermal comfort, and thermal energy storage.

Polyhedral Oligomeric Silsesquioxane (POSS)-Modified Thermoplastic and Thermosetting Nanocomposites: A Review

2008 ◽  
Vol 16 (8) ◽  
pp. 483-500 ◽  
Author(s):  
Jianqing Zhao ◽  
Yi Fu ◽  
Shumei Liu
Keyword(s):  
Processing Condition ◽  
Polyhedral Oligomeric Silsesquioxane ◽  
Physical And Mechanical Properties ◽  
Molecular Geometry ◽  
Surface Hydrophobicity ◽  
Dielectric Constants ◽  
Great Promise ◽  
Wide Range ◽  
Oligomeric Silsesquioxane ◽  
Mechanical Strengths

Polyhedral oligomeric silsesquioxane (POSS) nanoparticles have been successfully incorporated into thermoplastic and thermoset polymers via copolymerization, grafting, blending, surface bonding, or other transformations. A great promise in the development of a wide range of POSS-containing nanocomposites with diversely improved properties has been displayed. Thermal properties, viscoelastic properties, mechanical strengths, dielectric constants, surface hydrophobicity and flame-retardancy of the nanocomposites are easily varied to target properties by adjusting POSS structure, crosslink density, processing condition, etc. Investigations on the effects of POSS molecular geometry, composition, and concentration on physical and mechanical properties of resultant POSS-modified thermoplastic and thermosetting nanocomposites have been carefully reviewed in this article.

scholarly journals Activation of the receptor tyrosine kinase RET improves long-term hematopoietic stem cell outgrowth and potency

Blood ◽  
2020 ◽  
Vol 136 (22) ◽  
pp. 2535-2547 ◽  
Author(s):  
W. Grey ◽  
R. Chauhan ◽  
M. Piganeau ◽  
H. Huerga Encabo ◽  
M. Garcia-Albornoz ◽  
...  
Keyword(s):  
Intracellular Signaling ◽  
Culture Conditions ◽  
Cellular Growth ◽  
Great Promise ◽  
Bone Marrow Niche ◽  
Hematopoietic Stem ◽  
Intracellular Signaling Pathway ◽  
Wide Range

Abstract Expansion of human hematopoietic stem cells (HSCs) is a rapidly advancing field showing great promise for clinical applications. Recent evidence has implicated the nervous system and glial family ligands (GFLs) as potential drivers of hematopoietic survival and self-renewal in the bone marrow niche; how to apply this process to HSC maintenance and expansion has yet to be explored. We show a role for the GFL receptor, RET, at the cell surface of HSCs in mediating sustained cellular growth, resistance to stress, and improved cell survival throughout in vitro expansion. HSCs treated with the key RET ligand/coreceptor complex, glial-derived neurotrophic factor and its coreceptor, exhibit improved progenitor function at primary transplantation and improved long-term HSC function at secondary transplantation. Finally, we show that RET drives a multifaceted intracellular signaling pathway, including key signaling intermediates protein kinase B, extracellular signal-regulated kinase 1/2, NF-κB, and p53, responsible for a wide range of cellular and genetic responses that improve cell growth and survival under culture conditions.

Strain-engineering in AlGaN/GaN HEMTs: impact of silicon nitride passivation layer on electrical performance

2021 ◽  
Author(s):  
Sanghamitra Das ◽  
Taraprasanna Dash ◽  
Devika Jena ◽  
Eleena Mohapatra ◽  
C K Maiti
Keyword(s):  
Experimental Data ◽  
Compressive Strain ◽  
Cutoff Frequency ◽  
Strain Engineering ◽  
Electrical Performance ◽  
Current Gain ◽  
Great Promise ◽  
High Electron ◽  
Wide Range ◽  
Gan Hemts

Abstract In this work, we present a physics-based analysis of two-dimensional electron gas (2DEG) sheet carrier density and other microwave characteristics such as transconductance and cutoff frequency of AlxGa1-xN/GaN high electron mobility transistors (HEMT). An accurate polarization-dependent charge control-based analysis is performed for microwave performance assessment in terms of current, transconductance, gate capacitances, and cutoff frequency of lattice-mismatched AlGaN/GaN HEMTs. The influence of stress on spontaneous and piezoelectric polarization is included in the simulation of an AlGaN/GaN HEMT. We have shown the change in threshold voltage (Vt) due to tensile and compressive strain with different gate lengths. Also, the influence of stress due to the change in nitride thickness is presented. Our simulation results for drain current, transconductance, and current-gain cutoff frequency for various gate length devices are calibrated and verified with experimental data over a wide range of gate and drain applied voltages, which are expected to be useful for microwave circuit design. The predicted transconductance, drain conductance, and operation frequency are quite close to the experimental data. The AlGaN/GaN heterostructure HEMTs with nitride passivation layers show great promise as a candidate in future high speed and high power applications.

Stories, Lives, and Basic Survival: A Refinement and Defense of the Narrative View

2007 ◽  
Vol 60 ◽  
pp. 155-178
Author(s):  
Marya Schechtman
Keyword(s):  
Personal Identity ◽  
Narrative Identity ◽  
Human Existence ◽  
Narrative Form ◽  
Great Promise ◽  
Narrative Approach ◽  
Good Story ◽  
Wide Range ◽  
Intractable Problems

Everyone loves a good story. But does everyone live a good story? It has frequently been asserted by philosophers, psychologists and others interested in understanding the distinctive nature of human existence that our lives do, or should, take a narrative form. Over the last few decades there has been a steady and growing focus on this narrative approach within philosophical discussions of personal identity, resulting in a wide range of narrative identity theories. While the narrative approach has shown great promise as a tool for addressing longstanding and intractable problems of personal identity, it has also given rise to much suspicion. Opponents of this approach charge it with overstating or distorting the structure of actual lives.

Functional Contacts With a Range of Splicing Proteins Suggest a Central Role for Brr2p in the Dynamic Control of the Order of Events in Spliceosomes ofSaccharomyces cerevisiae

Genetics ◽  
2001 ◽  
Vol 157 (4) ◽  
pp. 1451-1467 ◽  
Author(s):  
Rob W van Nues ◽  
Jean D Beggs
Keyword(s):  
Protein Interactions ◽  
Dynamic Control ◽  
Splicing Factors ◽  
Functional Protein ◽  
U6 Snrna ◽  
Wide Range ◽  
Snrnp Protein ◽  
Associated Proteins ◽  
Step Factor ◽  
Hybrid Screening

AbstractMapping of functional protein interactions will help in understanding conformational rearrangements that occur within large complexes like spliceosomes. Because the U5 snRNP plays a central role in pre-mRNA splicing, we undertook exhaustive two-hybrid screening with Brr2p, Prp8p, and other U5 snRNP-associated proteins. DExH-box protein Brr2p interacted specifically with five splicing factors: Prp8p, DEAH-box protein Prp16p, U1 snRNP protein Snp1p, second-step factor Slu7p, and U4/U6.U5 tri-snRNP protein Snu66p, which is required for splicing at low temperatures. Co-immunoprecipitation experiments confirmed direct or indirect interactions of Prp16p, Prp8p, Snu66p, and Snp1p with Brr2p and led us to propose that Brr2p mediates the recruitment of Prp16p to the spliceosome. We provide evidence that the prp8-1 allele disrupts an interaction with Brr2p, and we propose that Prp8p modulates U4/U6 snRNA duplex unwinding through another interaction with Brr2p. The interactions of Brr2p with a wide range of proteins suggest a particular function for the C-terminal half, bringing forward the hypothesis that, apart from U4/U6 duplex unwinding, Brr2p promotes other RNA rearrangements, acting synergistically with other spliceosomal proteins, including the structurally related Prp2p and Prp16p. Overall, these protein interaction studies shed light on how splicing factors regulate the order of events in the large spliceosome complex.

scholarly journals Radar-Based Non-Contact Continuous Identity Authentication

2020 ◽  
Vol 12 (14) ◽  
pp. 2279 ◽  
Author(s):  
Shekh Md Mahmudul Islam ◽  
Olga Borić-Lubecke ◽  
Yao Zheng ◽  
Victor M. Lubecke
Keyword(s):  
Doppler Radar ◽  
Vital Signs ◽  
Identity Authentication ◽  
Future Research ◽  
Great Promise ◽  
Healthcare Applications ◽  
Privacy Concerns ◽  
Vital Signs Monitoring ◽  
Wide Range ◽  
Physiological Sensing

Non-contact vital signs monitoring using microwave Doppler radar has shown great promise in healthcare applications. Recently, this unobtrusive form of physiological sensing has also been gaining attention for its potential for continuous identity authentication, which can reduce the vulnerability of traditional one-pass validation authentication systems. Physiological Doppler radar is an attractive approach for continuous identity authentication as it requires neither contact nor line-of-sight and does not give rise to privacy concerns associated with video imaging. This paper presents a review of recent advances in radar-based identity authentication systems. It includes an evaluation of the applicability of different research efforts in authentication using respiratory patterns and heart-based dynamics. It also identifies aspects of future research required to address remaining challenges in applying unobtrusive respiration-based or heart-based identity authentication to practical systems. With the advancement of machine learning and artificial intelligence, radar-based continuous authentication can grow to serve a wide range of valuable functions in society.

scholarly journals Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer

2014 ◽  
Vol 42 (4) ◽  
pp. 1017-1023 ◽  
Author(s):  
Carlos Martinez-Perez ◽  
Carol Ward ◽  
Graeme Cook ◽  
Peter Mullen ◽  
Donald McPhail ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Potential Application ◽  
Great Promise ◽  
Effective Mechanism ◽  
Cycle Arrest ◽  
Antioxidant Agents ◽  
Wide Range ◽  
Anti Cancer ◽  
Oestrogen Signalling ◽  
Anti Tumour Effect

Flavonoids are a large group of ubiquitous polyphenolic secondary metabolites in plants with a wide range of properties, including a widely reported anti-cancer effect. The present review focuses on the different known mechanisms partaking in said anti-tumour effects, with particular emphasis on breast cancer. Their structure and reactivity allows flavonoids to work as antioxidant agents and phyto-oestrogens, modulating oestrogen signalling and metabolism to induce an overall anti-proliferative response. Other effects include the ability of flavonoids to modulate the CYP1 (cytochrome P450 1) and ABC (ATP-binding cassette) protein families, involved in carcinogenesis and drug delivery respectively. They can also induce apoptosis and cell cycle arrest and regulate other signalling pathways involved in the development and progression of cancer. In conclusion, there is accumulating evidence on the versatility of flavonoids and the numerous activities contributing to their anti-tumour effect. The complex, yet effective, mechanism of action of flavonoids, together with their interesting pharmacological properties, is the basis for their potential application in breast and other cancers. This rationale has led to the current interest in the application of flavonoids, including clinical trials currently underway and the development of novel flavonoids with improved properties, which hold great promise for tackling breast cancer.

scholarly journals Cellulose Nanocrystals/Graphene Hybrids—A Promising New Class of Materials for Advanced Applications

Nanomaterials ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1523 ◽  
Author(s):  
Djalal Trache ◽  
Vijay Kumar Thakur ◽  
Rabah Boukherroub
Keyword(s):  
Cellulose Nanocrystals ◽  
Renewable Resources ◽  
Food Packaging ◽  
Environmental Concern ◽  
Physicochemical Characteristics ◽  
Great Promise ◽  
New Class ◽  
Wide Range ◽  
Key Features ◽  
Basic Concepts

With the growth of global fossil-based resource consumption and the environmental concern, there is an urgent need to develop sustainable and environmentally friendly materials, which exhibit promising properties and could maintain an acceptable level of performance to substitute the petroleum-based ones. As elite nanomaterials, cellulose nanocrystals (CNC) derived from natural renewable resources, exhibit excellent physicochemical properties, biodegradability and biocompatibility and have attracted tremendous interest nowadays. Their combination with other nanomaterials such as graphene-based materials (GNM) has been revealed to be useful and generated new hybrid materials with fascinating physicochemical characteristics and performances. In this context, the review presented herein describes the quickly growing field of a new emerging generation of CNC/GNM hybrids, with a focus on strategies for their preparation and most relevant achievements. These hybrids showed great promise in a wide range of applications such as separation, energy storage, electronic, optic, biomedical, catalysis and food packaging. Some basic concepts and general background on the preparation of CNC and GNM as well as their key features are provided ahead.

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