Advances in surface plasmon resonance biosensing research

Nanoscale ◽  
2021 ◽  
Author(s):  
Qi Wang ◽  
Zihan Ren ◽  
Wan-Ming Zhao ◽  
Lei Wang ◽  
Xin Yan ◽  
...  
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Rapid Detection ◽  
High Sensitivity ◽  
Label Free ◽  
Surface Plasmon Reso

The surface plasmon reso-nance (SPR) phenomenon is of wide interest for its sen-sitivity to changes in sur-face refractive index for label-free, high sensitivity and rapid detection of bi-omarkers. This paper...

scholarly journals Reusable TiN Substrate for Surface Plasmon Resonance Heterodyne Phase Interrogation Sensor

Nanomaterials ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 1325 ◽  
Author(s):  
Ru-Jing Sun ◽  
Hung Ji Huang ◽  
Chien-Nan Hsiao ◽  
Yu-Wei Lin ◽  
Bo-Huei Liao ◽  
...  
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
High Sensitivity ◽  
Nanorod Array ◽  
Glass Substrates ◽  
Sensing Applications ◽  
Bulk Charge ◽  
Phase Interrogation

A TiN-based substrate with high reusability presented high-sensitivity refractive index measurements in a home-built surface plasmon resonance (SPR) heterodyne phase interrogation system. TiN layers with and without additional inclined-deposited TiN (i-TiN) layers on glass substrates reached high bulk charge carrier densities of 1.28 × 1022 and 1.91 × 1022 cm−3, respectively. The additional 1.4 nm i-TiN layer of the nanorod array presented a detection limit of 6.1 × 10−7 RIU and was higher than that of the 46 nm TiN layer at 1.2 × 10−6 RIU when measuring the refractive index of a glucose solution. Furthermore, the long-term durability of the TiN-based substrate demonstrated by multiple processing experiments presented a high potential for various practical sensing applications.

scholarly journals Refractive Index Sensing through Surface Plasmon Resonance in Light-Diffusing Fibers

2018 ◽  
Vol 8 (7) ◽  
pp. 1172 ◽  
Author(s):  
Nunzio Cennamo ◽  
Luigi Zeni ◽  
Ester Catalano ◽  
Francesco Arcadio ◽  
Aldo Minardo
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Optical Fiber Sensor ◽  
Fiber Surface ◽  
High Sensitivity ◽  
Refractive Index Sensing ◽  
Sensor Platform ◽  
Chemical Procedure

In this paper, we show that light-diffusing fibers (LDF) can be efficiently used as host material for surface plasmon resonance (SPR)-based refractive index sensing. This novel platform does not require a chemical procedure to remove the cladding or enhance the evanescent field, which is expected to give better reproducibility of the sensing interface. The SPR sensor has been realized by first removing the cladding with a simple mechanical stripper, and then covering the unclad fiber surface with a thin gold film. The tests have been carried out using water–glycerin mixtures with refractive indices ranging from 1.332 to 1.394. The experimental results reveal a high sensitivity of the SPR wavelength to the outer medium’s refractive index, with values ranging from ~1500 to ~4000 nm/RIU in the analyzed range. The results suggest that the proposed optical fiber sensor platform could be used in biochemical applications.

scholarly journals High Sensitivity Photonic Crystal Fiber Refractive Index Sensor with Gold Coated Externally Based on Surface Plasmon Resonance

Micromachines ◽  
2018 ◽  
Vol 9 (12) ◽  
pp. 640 ◽  
Author(s):  
Xudong Li ◽  
Shuguang Li ◽  
Xin Yan ◽  
Dongming Sun ◽  
Zheng Liu ◽  
...  
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Photonic Crystal ◽  
Photonic Crystal Fiber ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
High Sensitivity ◽  
Refractive Index Sensor ◽  
Crystal Fiber ◽  
Air Hole

In this paper we propose a gold-plated photonic crystal fiber (PCF) refractive index sensor based on surface plasmon resonance (SPR), in which gold is coated on the external surface of PCF for easy fabrication and practical detection. The finite element method (FEM) is used for the performance analysis, and the numerical results show that the thickness of the gold film, the refractive index of the analyte, the radius of the air hole in the first layer, the second layer, and the central air hole can affect the sensing properties of the sensor. By optimizing the sensor structure, the maximum wavelength sensitivity can reach 11000 nm/RIU and the maximum amplitude sensitivity can reach 641 RIU−1. Due to its high sensitivity, the proposed sensor can be used for practical biological and chemical sensing.

scholarly journals High Sensitivity Surface Plasmon Resonance Sensor Based on Periodic Multilayer Thin Films

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3399
Author(s):  
Haoyuan Cai ◽  
Shihan Shan ◽  
Xiaoping Wang
Keyword(s):  
Refractive Index ◽  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Fdtd Method ◽  
High Sensitivity ◽  
Clinical Diagnostics ◽  
Resonance Sensor ◽  
Difference Time ◽  
Sensitivity Characteristic

Surface plasmon resonance (SPR) biosensors consisting of alternate layers of silver (Ag) and TiO2 thin film have been proposed as a high sensitivity biosensor. The structure not only prevents the Ag film from oxidation, but also enhances the field inside the structure, thereby improving the performance of the sensor. Genetic algorithm (GA) was used to optimize the proposed structure and its maximum angular sensitivity was 384°/RIU (refractive index unit) at the refractive index environment of 1.3425, which is about 3.12 times that of the conventional Ag-based biosensor. A detailed discussion, based on the finite difference time domain (FDTD) method, revealed that an enhanced evanescent field at the top layer–analyte region results in the ultra-sensitivity characteristic. We expect that the proposed structure can be a suitable biosensor for chemical detection, clinical diagnostics, and biological examination.

Surface Plasmon Resonance enhanced Common Path Interferometry for high sensitivity label free biomolecule interaction analysis

2007 ◽  
Author(s):  
Charles Greef ◽  
Viatcheslav Petropavlovskikh ◽  
Oyvind Nilsen ◽  
Bilge Hacioglu ◽  
Boris Khattatov ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Interaction Analysis ◽  
High Sensitivity ◽  
Label Free ◽  
Common Path

scholarly journals An Overview of Artificial Olfaction Systems with a Focus on Surface Plasmon Resonance for the Analysis of Volatile Organic Compounds

Biosensors ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 244
Author(s):  
Marielle El Kazzy ◽  
Jonathan S. Weerakkody ◽  
Charlotte Hurot ◽  
Raphaël Mathey ◽  
Arnaud Buhot ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Volatile Organic Compounds ◽  
Organic Compounds ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
High Sensitivity ◽  
Label Free ◽  
Electronic Noses ◽  
Prism Coupler ◽  
Volatile Organic

The last three decades have witnessed an increasing demand for novel analytical tools for the analysis of gases including odorants and volatile organic compounds (VOCs) in various domains. Traditional techniques such as gas chromatography coupled with mass spectrometry, although very efficient, present several drawbacks. Such a context has incited the research and industrial communities to work on the development of alternative technologies such as artificial olfaction systems, including gas sensors, olfactory biosensors and electronic noses (eNs). A wide variety of these systems have been designed using chemiresistive, electrochemical, acoustic or optical transducers. Among optical transduction systems, surface plasmon resonance (SPR) has been extensively studied thanks to its attractive features (high sensitivity, label free, real-time measurements). In this paper, we present an overview of the advances in the development of artificial olfaction systems with a focus on their development based on propagating SPR with different coupling configurations, including prism coupler, wave guide, and grating.

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