Poly(2-Ethyl-2-Oxazoline-co-Ethyleneimine)-block-Poly(ɛ-Caprolactone) Based Micelles: Synthesis, Characterization, Peptide Conjugation and Cytotoxic Activitiy

2021 ◽  
Author(s):  
Sevgi Gulyuz ◽  
Umut Ugur OZKOSE ◽  
Melek Parlak Khalily ◽  
Mehmet Seckin Kesici ◽  
Polen Kocak ◽  
...  

Here we present self-assembled polymeric micelles as potential delivery systems for therapeutic agents with highly tunable properties. The major goal of this study is to design breast and prostate cancer...

2018 ◽  
Author(s):  
E. Tonsing-Carter ◽  
T. Long ◽  
D.C. West ◽  
R. Harkless ◽  
D.N. Dolcen ◽  
...  

2017 ◽  
Vol 18 (11) ◽  
Author(s):  
Rohit R. Bhosale ◽  
H. V. Gangadharappa ◽  
Umme Hani ◽  
Riyaz Ali M. Osmani ◽  
Rudra Vaghela ◽  
...  

2020 ◽  
Vol 17 (10) ◽  
pp. 911-924
Author(s):  
Rohitas Deshmukh

Colon cancer is one of the most prevalent diseases, and traditional chemotherapy has not been proven beneficial in its treatment. It ranks second in terms of mortality due to all cancers for all ages. Lack of selectivity and poor biodistribution are the biggest challenges in developing potential therapeutic agents for the treatment of colon cancer. Nanoparticles hold enormous prospects as an effective drug delivery system. The delivery systems employing the use of polymers, such as chitosan and pectin as carrier molecules, ensure the maximum absorption of the drug, reduce unwanted side effects and also offer protection to the therapeutic agent from quick clearance or degradation, thus allowing an increased amount of the drug to reach the target tissue or cells. In this systematic review of published literature, the author aimed to assess the role of chitosan and pectin as polymer-carriers in colon targeted delivery of drugs in colon cancer therapy. This review summarizes the various studies employing the use of chitosan and pectin in colon targeted drug delivery systems.


2021 ◽  
Vol 9 (5) ◽  
pp. 2754-2763
Author(s):  
Kenya Kani ◽  
Hyunsoo Lim ◽  
Andrew E. Whitten ◽  
Kathleen Wood ◽  
Anya J. E. Yago ◽  
...  

The mesoporous RhNi alloy films are synthesized by controlling the concentration of Rh precursor, applied potentials, and pH via the electrochemical co-deposition method with self-assembled polymeric micelles templates for enhancing electrocatalytic properties.


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