A novel fast-responsive fluorescent probe based on 1, 3, 5-triazine for endogenous H2S detection with large Stokes shift and its application in cell imaging

2021 ◽  
Author(s):  
Zhi-Hao Zhang ◽  
Shaoqing Li ◽  
Yizhe Yan ◽  
Jianbo Qu ◽  
Jian-Yong Wang
Keyword(s):  
Fluorescent Probe ◽  
Cell Imaging ◽  
Stokes Shift ◽  
Living Cells ◽  
Large Stokes Shift ◽  
Turn On ◽  
H2s Detection

A novel fast-responsive fluorescent probe TzAr-H2S was constructed to realize the imaging of endogenous H2S in living cells. This turn-on fluorescent probe TzAr-H2S can quickly (only 20 s) detect H2S...

A novel “turn-on” fluorescent probe with a large stokes shift for homocysteine and cysteine: Performance in living cells and zebrafish

2018 ◽  
Vol 259 ◽  
pp. 233-240 ◽  
Author(s):  
Haohan Song ◽  
Junli Zhang ◽  
Xiao Wang ◽  
Yanmei Zhou ◽  
Chenggong Xu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Living Cells ◽  
Large Stokes Shift ◽  
Turn On

A highly selective ESIPT-based fluorescent probe with a large Stokes shift for the turn-on detection of cysteine and its application in living cells

2019 ◽  
Vol 160 ◽  
pp. 48-57 ◽  
Author(s):  
Huace Sheng ◽  
Yonghong Hu ◽  
Yi Zhou ◽  
Shimin Fan ◽  
Yang Cao ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Stokes Shift ◽  
Living Cells ◽  
Large Stokes Shift ◽  
Turn On

A novel near-infrared and naked-eyes turn on fluorescent probe for detection of biothiols with a large Stokes shift and its application in living cells

2018 ◽  
Vol 10 (32) ◽  
pp. 3991-3999 ◽  
Author(s):  
Wang Zhang ◽  
Gu Weijing ◽  
Tian Cheng ◽  
Bingxiang Wang ◽  
Yuliang Jiang ◽  
...  
Keyword(s):  
Amino Acids ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Stokes Shift ◽  
Living Cells ◽  
Selective Detection ◽  
Large Stokes Shift ◽  
Turn On

A novel turn-on fluorescent probe (DDND) for highly selective detection of biothiols over other amino acids was synthesized and investigated in this work, which used the 2,4-dinitrobenzenesulfonyl group as a fluorescent quencher.

Near-infrared fluorogenic switches for the detection of Hg(ii) ions: applications in real samples and living cells

2019 ◽  
Vol 11 (21) ◽  
pp. 2769-2777 ◽  
Author(s):  
Asaithambi Gomathi ◽  
Periasamy Viswanathamurthi
Keyword(s):  
Fluorescent Probe ◽  
Near Infrared ◽  
Cell Imaging ◽  
Limit Of Detection ◽  
Stokes Shift ◽  
Living Cells ◽  
Imaging Studies ◽  
Real Samples ◽  
Large Stokes Shift

A novel near-infrared fluorescent probe NIRM was designed and synthesized. The probe exhibited a low limit of detection for Hg2+ (3.2 nM) as well as a large Stokes shift (115 nm), which is very favorable for cell imaging studies.

scholarly journals Design and Synthesis of a Fluorescent Probe with a Large Stokes Shift for Detecting Thiophenols and Its Application in Water Samples and Living Cells

Molecules ◽  
2019 ◽  
Vol 24 (2) ◽  
pp. 375 ◽  
Author(s):  
Hua Liu ◽  
Chuanlong Guo ◽  
Shuju Guo ◽  
Lijun Wang ◽  
Dayong Shi
Keyword(s):  
Response Time ◽  
Metal Ions ◽  
Fluorescent Probe ◽  
Water Samples ◽  
Stokes Shift ◽  
Living Cells ◽  
Electron Transfer Mechanism ◽  
Short Response Time ◽  
Large Stokes Shift ◽  
Turn On

A turn-on florescent probe (probe-KCP) was developed for highly selective detection of thiophenols based on a donor-excited photo-induced electron transfer mechanism. Herein, the synthesis of the probe, a chalcone derivative, through a simple straightforward combination of a carbazole-chalcone fluorophore with a 2,4-dinitrophenyl functional group. In a kinetic study of the probe-KCP for thiophenols, the probe displayed a short response time (~30 min) and significant fluorescence enhancement. In selection and competition experiments, the probe-KCP exhibited excellent selectivity for thiophenols over glutathione (GSH), cysteine (Cys), sodium hydrosulfide (NaSH), and ethanethiol (C2H5SH) in addition to common anions and metal ions. Using the designed probe, we successfully monitored and quantified thiophenols, which are highly toxic. This turn-on fluorescence probe features a remarkably large Stokes shift (130 nm) and a short response time (30 min), and it is highly selective and sensitive (~160-fold) in the detection of thiophenols, with marked fluorescence in the presence of thiophenols. probe-KCP responds to thiophenols with a good range of linearity (0–15 μM) and a detection limit of 28 nM (R2 = 0.9946) over other tested species mentioned including aliphatic thiols, thiophenol analogues, common anions, and metal ions. The potential applications of this carbazole-chalcone fluorescent probe was successfully used to determine of thiophenols in real water samples and living cells with good performance and low cytotoxicity. Therefore, this probe has great potential application in environment and biological samples.

Novel Cu2+-specific “Turn-ON” fluorescent probe based on [5]helicene with very large Stokes shift and its potential application in living cells

2018 ◽  
Vol 42 (7) ◽  
pp. 5540-5547 ◽  
Author(s):  
Nirawit Kaewnok ◽  
Anuwut Petdum ◽  
Jitnapa Sirirak ◽  
Adisri Charoenpanich ◽  
Waraporn Panchan ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
Potential Application ◽  
Stokes Shift ◽  
Living Cells ◽  
Cellular System ◽  
Large Stokes Shift ◽  
Turn On ◽  
Low Detection Limit ◽  
System P

The sensor provides Cu2+-sensitive with low detection limit and very large Stokes shift, and can induce the emission in the HepG2 cellular system.

A turn-on near-infrared fluorescent probe with rapid response and large Stokes shift for the selective and sensitive detection of zinc(ii) and its application in living cells

2019 ◽  
Vol 11 (18) ◽  
pp. 2396-2403 ◽  
Author(s):  
Weixia Zhang ◽  
Xinxin Jin ◽  
Wei Chen ◽  
Chunhui Jiang ◽  
Hongfei Lu
Keyword(s):  
Fluorescent Probe ◽  
Rapid Detection ◽  
Near Infrared ◽  
Limit Of Detection ◽  
Stokes Shift ◽  
Living Cells ◽  
Rapid Response ◽  
Sensitive Detection ◽  
Large Stokes Shift ◽  
Turn On

Herein, a new near-infrared turn-on fluorescent probe, YPT, was designed and synthesized for the rapid detection of Zn2+, which exhibited low limit of detection for Zn2+ (12 nM) as well as a favorable large Stokes shift (λem − λex = 168 nm).

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