Paper-based DNA Sensor enabling Colorimetric Assay Integrated with Smartphone for Human Papillomavirus Detection

2021 ◽  
Author(s):  
Sarida Naorungroj ◽  
Prinjaporn Teengam ◽  
Tirayut Vilaivan ◽  
Orawon Chailapakul
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Sexually Transmitted Infections ◽  
Colorimetric Assay ◽  
Dna Sensor ◽  
Sexually Transmitted

Human papillomavirus (HPV) is one of the most common sexually transmitted infections which causes cervical cancer in women. In order to avoid the development of cancer and the onset of...

scholarly journals P2-164 Human papillomavirus, other sexually transmitted infections and risk of cervical cancer. A Nordic Joint Study

2011 ◽  
Vol 65 (Suppl 1) ◽  
pp. A266-A266
Author(s):  
T. Luostarinen ◽  
L. A. Dahlstrom ◽  
K. Andersson ◽  
H. Ogmundsdottir ◽  
E. Jellum ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Sexually Transmitted Infections ◽  
Sexually Transmitted ◽  
Joint Study

scholarly journals Association between asymptomatic sexually transmitted infections and high-risk human papillomavirus in cervical lesions

2019 ◽  
Vol 47 (11) ◽  
pp. 5548-5559 ◽  
Author(s):  
Lei Wang ◽  
Lizhe Zhu ◽  
Han Li ◽  
Nan Ma ◽  
Huifang Huang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
High Risk ◽  
Sexually Transmitted Infections ◽  
Low Grade ◽  
Squamous Intraepithelial Lesion ◽  
Cervical Lesions ◽  
Sexually Transmitted ◽  
Increased Risk ◽  
Intraepithelial Lesion

Objective This study aimed to determine the association of asymptomatic sexually transmitted infections (STIs), including Ureaplasma urealyticum (UU), Mycoplasma hominis (MH), Mycoplasma genitalium, Chlamydia trachomatis, and herpes simplex virus type 2, with high-risk human papillomavirus (hrHPV) in cervical intraepithelial lesions and neoplasms. Methods A total of 320 hrHPV-positive and 160 hrHPV-negative women were divided into high-grade squamous intraepithelial lesion (HSIL) + invasive cervical cancer and low-grade squamous intraepithelial lesion + normal subgroups, respectively, on the basis of pathological cervical lesions. Cervical brush specimens were amplified and hybridized using polymerase chain reaction kits. Results MH was associated with hrHPV infection, but not with specific hrHPV genotypes or with single or multiple genotypes. Coinfection of hrHPV and UU serotype 14 (Uup14) showed an increased risk of HSILs and cervical carcinoma (odds ratio [OR]: 12.541, 95% confidence interval [CI]: 3.625–43.390). U. urealyticum biovar (Uuu) and Uup1 infections showed a similar increased risk (OR: 11.646, 95% CI: 1.493–90.850; OR: 7.474, 95% CI: 1.140–49.015, respectively) without hrHPV. Conclusions Asymptomatic STIs are widespread. This study shows an association between UU subtypes and cervical cancer, providing new insight into cervical lesion etiology. Screening for MH, Uup14, Uup1, and Uuu is important under different hrHPV statuses.

Human papillomavirus infection and associated factors for cervical intraepithelial neoplasia in women living with HIV in China: a cross-sectional study

2018 ◽  
Vol 95 (2) ◽  
pp. 140-144 ◽  
Author(s):  
Qian Wang ◽  
Xiaomeng Ma ◽  
Xiaosong Zhang ◽  
Jason J Ong ◽  
Jun Jing ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Human Papillomavirus ◽  
Cervical Intraepithelial Neoplasia ◽  
Sexually Transmitted Infections ◽  
Associated Factors ◽  
Intraepithelial Neoplasia ◽  
Multivariate Logistic Regression ◽  
Sexually Transmitted ◽  
Women Living With Hiv ◽  
Living With Hiv

ObjectiveWomen living with HIV (WLHIV) face disproportionately higher risks of acquiring human papillomavirus (HPV) compared with HIV negative counterparts. We aimed to investigate the prevalence of HPV in WLHIV in Chinese hospital setting and identify associated factors to the progression of late-stage cervical intraepithelial neoplasia (CIN2+) in this population.MethodThis retrospective study collected data from 183 WLHIV on antiretroviral treatment (ART), based on reproductive health questionnaires. Gynaecological examination results including serum (for HIV viral load, CD4 T-cell count, hepatitis B infections, syphilis) and vaginal swabs for common bacterial sexually transmitted infections (STIs). Multivariate-logistic regression was applied to analyze the contributing factors to CIN2+.ResultsHIV coinfection with other Sexually Transmitted Infections (STIs) were observed in 99 participants (54.1%, (99/183)). HPV (43.7% (80/183)) was the most prevalent STI. The three most prevalent HPV subtypes were all high-risk HPV (HR-HPV), including HPV52 (33.8% (27/80)), HPV58 (21.3% (17/80)) and HPV33 (13.75% (11/80)). About a third (37.5%, 30/80) of women with HPV had HR-HPV. Multiple HPV coinfections were common in HIV-HPV coinfected women (41.3%, 33/80). Cytological examinations revealed that 77.5% (62/80) HPV+ women had detectable cervical lesions. In comparison, only 4.9% (5/103) HPV negative womenwith Atypia and 1.0% (1/103) with CIN1 were diagnosed. Multivariate logistic regression revealed that HPV16 (OR=19.04, 2.53 to 122.92; p=0.004) and HPV18 (OR=11.54, 1.45 to 91.64; p=0.021) infections were significantly associated with CIN2+ in HIV-HPV coinfected women.ConclusionA high prevalence of HPV was found in women on ART. HPV16/18 infection are strong associated factors to CIN2+ in HIV-HPV coinfected women.

scholarly journals Sexually Transmitted Infections and Male Circumcision: A Systematic Review and Meta-Analysis

ISRN Urology ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-42 ◽  
Author(s):  
Robert S. Van Howe
Keyword(s):  
Systematic Review ◽  
Human Papillomavirus ◽  
Sexually Transmitted Infections ◽  
Sexually Transmitted Infection ◽  
Positive Impact ◽  
Meta Analysis ◽  
Transmitted Infection ◽  
Sexually Transmitted ◽  
General Populations ◽  
Simplex Virus

The claim that circumcision reduces the risk of sexually transmitted infections has been repeated so frequently that many believe it is true. A systematic review and meta-analyses were performed on studies of genital discharge syndrome versus genital ulcerative disease, genital discharge syndrome, nonspecific urethritis, gonorrhea, chlamydia, genital ulcerative disease, chancroid, syphilis, herpes simplex virus, human papillomavirus, and contracting a sexually transmitted infection of any type. Chlamydia, gonorrhea, genital herpes, and human papillomavirus are not significantly impacted by circumcision. Syphilis showed mixed results with studies of prevalence suggesting intact men were at great risk and studies of incidence suggesting the opposite. Intact men appear to be of greater risk for genital ulcerative disease while at lower risk for genital discharge syndrome, nonspecific urethritis, genital warts, and the overall risk of any sexually transmitted infection. In studies of general populations, there is no clear or consistent positive impact of circumcision on the risk of individual sexually transmitted infections. Consequently, the prevention of sexually transmitted infections cannot rationally be interpreted as a benefit of circumcision, and any policy of circumcision for the general population to prevent sexually transmitted infections is not supported by the evidence in the medical literature.

Sexually transmitted infections

2021 ◽  
pp. 603-628
Author(s):  
Henrietta Williams
Keyword(s):  
Human Papillomavirus ◽  
Bacterial Vaginosis ◽  
Sexually Transmitted Infections ◽  
Genital Herpes ◽  
Genital Warts ◽  
Syndromic Management ◽  
Sexually Transmitted ◽  
Granuloma Inguinale ◽  
Chlamydial Infections

Why are sexually-transmitted infections important??, Syndromic management of sexually-transmitted infections?, Syphilis?, Gonorrhoea?, Chlamydial infections?, Chancroid?, Granuloma inguinale donovanosis?, Trichomoniasis?, Bacterial vaginosis?, Genital herpes?, Candida vaginitis?, Human papillomavirus and genital warts?

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