scholarly journals CARBON DOTS: A NOVEL PLATFORM FOR BIOMEDICAL APPLICATION

2021 ◽  
Author(s):  
Mohammadreza Behi ◽  
Leila Gholami ◽  
Sina Naficy ◽  
Stefano Palomba ◽  
Fariba Dehghani
Keyword(s):  
Carbon Dots ◽  
Biomedical Application ◽  
Distinctive Features ◽  
Carbon Based

Carbon dots (CDs) are a latterly synthesised class of carbon-based nanostructures known as zero-dimensional (0D) nanomaterials, which have drawn a great deal of researcher’s attention owing to their distinctive features,...

scholarly journals A Facile Co-crystallization Approach to Fabricate Two-component Carbon Dots Composites Showing Time-Dependent Evolutive Room Temperature Phosphorescence Colors

2021 ◽  
Author(s):  
Jian Qu ◽  
Xin Zhang ◽  
Zhong-Jie Wang ◽  
Shuyan Zhang ◽  
Yejian Yu ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Room Temperature ◽  
Data Encryption ◽  
Time Dependent ◽  
Security Level ◽  
Room Temperature Phosphorescence ◽  
Two Component ◽  
Carbon Based

Time-dependent evolutive afterglow materials can increase the security level by providing additional encryption modes in anti-counterfeiting and data encryption. The design of carbon-based materials with dynamic afterglow colors is attractive...

Review of long wavelength luminescent carbon-based nanomaterials: preparation, biomedical application and future challenges

2020 ◽  
Vol 56 (4) ◽  
pp. 2814-2837
Author(s):  
Feng Huo ◽  
Wenqiong Li ◽  
Yuhang Liu ◽  
Xiaohong Liu ◽  
Chong-Yew Lee ◽  
...  
Keyword(s):  
Biomedical Application ◽  
Long Wavelength ◽  
Future Challenges ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

scholarly journals Nanotheranostic Carbon Dots as an Emerging Platform for Cancer Therapy

2020 ◽  
Vol 1 (1) ◽  
pp. 58-77
Author(s):  
Sumiya Adrita ◽  
Khandaker Tasnim ◽  
Ji Ryu ◽  
Shazid Sharker
Keyword(s):  
Cancer Treatment ◽  
Carbon Dots ◽  
High Surface ◽  
High Surface Area ◽  
Volume Ratio ◽  
Biomedical Sciences ◽  
Diagnosis And Therapy ◽  
Low Dimensional ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

Cancer remains one of the most deadly diseases globally, but carbon-based nanomaterials have the potential to revolutionize cancer diagnosis and therapy. Advances in nanotechnology and a better understanding of tumor microenvironments have contributed to novel nanotargeting routes that may bring new hope to cancer patients. Several low-dimensional carbon-based nanomaterials have shown promising preclinical results; as such, low-dimensional carbon dots (CDs) and their derivatives are considered up-and-coming candidates for cancer treatment. The unique properties of carbon-based nanomaterials are high surface area to volume ratio, chemical inertness, biocompatibility, and low cytotoxicity. It makes them well suited for delivering chemotherapeutics in cancer treatment and diagnosis. Recent studies have shown that the CDs are potential applicants in biomedical sciences, both as nanocarriers and nanotransducers. This review covers the most commonly used CD nanoparticles in nanomedicines intended for the early diagnosis and therapy of cancer.

scholarly journals B- and N-doped carbon dots by one-step microwave hydrothermal synthesis: tracking yeast status and imaging mechanism

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Bo Tian ◽  
Tianxin Fu ◽  
Yang Wan ◽  
Yun Ma ◽  
Yanbo Wang ◽  
...  
Keyword(s):  
Yeast Cell ◽  
Carbon Dots ◽  
Biomedical Application ◽  
Basic Research ◽  
Growth Status ◽  
Dose Time ◽  
Microwave Hydrothermal ◽  
One Step ◽  
Doped Carbon Dots ◽  
Energy Dependent

Abstract Background Carbon dots (CDs) are widely used in cell imaging due to their excellent optical properties, biocompatibility and low toxicity. At present, most of the research on CDs focuses on biomedical application, while there are few studies on the application of microbial imaging. Results In this study, B- and N-doped carbon dots (BN-CDs) were prepared from citric acid, ethylenediamine, and boric acid by microwave hydrothermal method. Based on BN-CDs labeling yeast, the dead or living of yeast cell could be quickly identified, and their growth status could also be clearly observed. In order to further observe the morphology of yeast cell under different lethal methods, six methods were used to kill the cells and then used BN-CDs to label the cells for imaging. More remarkably, imaging of yeast cell with ultrasound and antibiotics was significantly different from other imaging due to the overflow of cell contents. In addition, the endocytosis mechanism of BN-CDs was investigated. The cellular uptake of BN-CDs is dose, time and partially energy-dependent along with the involvement of passive diffusion. The main mechanism of endocytosis is caveolae-mediated. Conclusion BN-CDs can be used for long-term stable imaging of yeast, and the study provides basic research for applying CDs to microbiol imaging. Graphical Abstract

Green synthesis of Zingiberis rhizoma-based carbon dots attenuates chemical and thermal stimulus pain in mice

Nanomedicine ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. 851-869
Author(s):  
Meiling Zhang ◽  
Jinjun Cheng ◽  
Yue Zhang ◽  
Hui Kong ◽  
Suna Wang ◽  
...  
Keyword(s):  
Analgesic Activity ◽  
Carbon Dots ◽  
Functional Group ◽  
Biomedical Application ◽  
Chemical Stimulus ◽  
Thermal Stimulus ◽  
Hot Plate ◽  
Pyrolysis Method ◽  
Tail Immersion ◽  
Preliminary Study

Aim: To evaluate the analgesic activity of Zingiberis rhizoma-based carbon dots (ZR-CDs). Materials & methods: Novel ZR-CDs were prepared via a facile, green pyrolysis method. Microstructure, optical and functional group properties were characterized. Acetic acid writhing, hot-plate and tail-immersion tests were performed using mice to evaluate the analgesic activity of ZR-CDs, followed by a preliminary study on the analgesic mechanism. Results: ZR-CDs with a quantum yield of 5.2% had a diameter ranging from 2.23 to 3.77 nm. Remarkable analgesic effect of ZR-CDs was observed against both thermal and chemical stimulus tests, possibly mediated by an opioid-like mechanism and the regulation of 5-hydroxytryptamine levels. Conclusion: ZR-CDs have a promising potential for biomedical application in relieving pain-related diseases.

scholarly journals Synthetic Approach to Rice Waste-Derived Carbon-Based Nanomaterials and Their Applications

2021 ◽  
Vol 1 (3) ◽  
pp. 109-159
Author(s):  
Shamroza Mubarik ◽  
Nawal Qureshi ◽  
Zainab Sattar ◽  
Aqeela Shaheen ◽  
Ambreen Kalsoom ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Dots ◽  
Carbon Nanomaterials ◽  
Agricultural Waste ◽  
Green Technology ◽  
Water Remediation ◽  
Synthetic Approach ◽  
Biomass Waste ◽  
Carbon Based Nanomaterials ◽  
Carbon Based

The utilization of biomass waste to produce valuable products has extraordinary advantages as far as both the economy and climate are concerned, which have become particularly significant lately. The large-scale manufacturing of agricultural waste, mainly rice by-products (rice husk, rice straw, and rice bran), empowers them to be the most broadly examined biomasses as they contain lignin, cellulose, and hemicellulose. Rice waste was first used to incorporate bulk materials, while the manufacturing of versatile nanostructures from rice waste at low cost has been developed in recent years and attracts much consideration nowadays. Carbon-based nanomaterials including graphene, carbon nanotubes, carbon dots, fullerenes, and carbon nanofibers have tremendous potential in climate and energy-related applications. Various methods have been reported to synthesize high-value carbon nanomaterials, but the use of green technology for the synthesis of carbon nanomaterials is most common nowadays because of the abundant availability of the starting precursor, non-toxicity, low fabrication cost, ease of modification, and eco-friendly nature; therefore, reusing low-value biomass waste for the processing of renewable materials to fabricate high-value products is remarkable. Carbon nanomaterials derived from rice waste have broad applications in various disciplines owing to their distinctive physicochemical, electrical, optical, mechanical, thermal, and enhanced biocompatibility properties. The main objective of this review and basic criteria of selecting examples and explanations is to highlight the green routes for the synthesis of carbon nanomaterials—i.e., graphene, carbon nanotubes, and carbon dots—from rice biomass waste, and their extensive applications in biomedical research (bio-imaging), environmental (water remediation), and energy-related (electrodes for supercapacitors, Li-ion battery, fuel cells, and solar cells) applications. This review summarizes recent advancements, challenges, and trends for rice waste obtained from renewable resources for utilization in the fabrication of versatile carbon-based nanomaterials.

scholarly journals Carbon Dots: A New Type of Carbon-Based Nanomaterial with Wide Applications

2020 ◽  
Vol 6 (12) ◽  
pp. 2179-2195
Author(s):  
Junjun Liu ◽  
Rui Li ◽  
Bai Yang
Keyword(s):  
Carbon Dots ◽  
New Type ◽  
Carbon Based

scholarly journals Carbon Dots: From Lab Synthesis to Unique Applications

2020 ◽  
Vol 2 (2) ◽  
pp. 45
Keyword(s):  
Carbon Dots ◽  
Building Blocks ◽  
Inhibitory Effect ◽  
Zebrafish Model ◽  
Preparation Methods ◽  
Body Tissues ◽  
Strong Inhibitory Effect ◽  
Amyloid Aβ ◽  
Drug Nanocarriers ◽  
Carbon Based

Carbon dots (CDs) are a group of relatively new carbon-based spherical nanoparticles (NPs) with diameters less than 10 nm. They are widely present in nature and can also be synthesized using various carbon-based substances as precursors by either top-down or bottom-up approaches. They are well characterized for tunable surface functionality, excellent photoluminescence (PL), high photostability and water dispersity, good biocompatibility, and nontoxicity. Also, they display different sizes and surface chemistry depending on the preparation methods, and precursors applied. Applications of CDs in drug delivery, bioimaging, sensing, optics, photocatalysis, and other nanotechnology fields are rapidly rising due to their aforementioned unique properties. In this presentation, I will focus on the preparation, characterization and several significant applications of the CDs developed in our group. Specifically, I will introduce one type of CDs in yellow powder (Y-CDs) together with their amphiphilicity, tunable PL, and nontoxicity. In addition, Y-CDs showed an excellent permeability of body tissues, even including the blood-brain barrier (BBB) via passive diffusion using a zebrafish model. Furthermore, Y-CDs exhibited a strong inhibitory effect on the secretion of amyloid precursor protein (APP) and beta-amyloid (Aβ), which is significant for the future treatment of Alzheimer’s disease (AD). Considering their excellent permeability, Y-CDs are also promising drug nanocarriers for the treatment of diverse viral diseases such as COVID-19. Another work I would like to share with the public is that CDs have proved to be promising Lego-like building blocks for the assembly of novel versatile drug nanocarriers to simultaneously fulfill multitasks.

Semi-transparent Luminescent Solar Concentrator based on Plasmonic-enhanced Carbon Dots

2021 ◽  
Author(s):  
Xin Liu ◽  
Daniele Benetti ◽  
Federico Rosei
Keyword(s):  
Carbon Dots ◽  
Simple Synthesis ◽  
Solar Concentrator ◽  
Solar Concentrators ◽  
Luminescent Solar Concentrators ◽  
Luminescent Solar Concentrator ◽  
Carbon Based

Carbon dots (Cdots), are emerging as eco-friendly alternative luminophore for luminescent solar concentrators (LSCs), due to their environmental and economical friendliness, and simple synthesis using abundant carbon-based sources. However, their...

Blood Coagulation System and Carbon-Based Nanoengineering for Biomedical Application

2021 ◽  
pp. 279-298
Author(s):  
Abhishek R. Panigrahi ◽  
Pooja Yadav ◽  
Samir K. Beura ◽  
Sunil K. Singh
Keyword(s):  
Blood Coagulation ◽  
Biomedical Application ◽  
Coagulation System ◽  
Blood Coagulation System ◽  
Carbon Based
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