A Surprisingly Gentle Approach to Cavity Containing Spherocylindrical Microparticles from Ordinary Polymer Dispersions in Flow

2021 ◽  
Author(s):  
Amit K. Tripathi ◽  
John G. Tsavalas
Keyword(s):  
Internal Cavity ◽  
Polymeric Microparticles ◽  
Polymer Dispersions

Herein, we demonstrate a facile approach to fully transform spherical polymeric microparticles to elongated spherocylinders containing an internal cavity under ambient and mild stirring conditions. Critical to the process is...

Internal cavity characteristics of northern long-eared bat (Myotis septentrionalis) maternity day-roosts

2015 ◽  
Author(s):  
Alexander Silvis ◽  
R. Edward Thomas ◽  
W. Mark Ford ◽  
Eric R. Britzke ◽  
Meryl J. Friedrich
Keyword(s):  
Internal Cavity ◽  
Myotis Septentrionalis ◽  
Cavity Characteristics

scholarly journals Cyclodextrins, Natural Compounds, and Plant Bioactives—A Nutritional Perspective

Biomolecules ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 401
Author(s):  
Svenja Wüpper ◽  
Kai Lüersen ◽  
Gerald Rimbach
Keyword(s):  
Intestinal Flora ◽  
Aqueous Solubility ◽  
Outer Wall ◽  
Natural Compounds ◽  
Model Organisms ◽  
Laboratory Model ◽  
Internal Cavity ◽  
Pentacyclic Triterpenoids ◽  
Starch Derivatives ◽  
Improved Stability

Cyclodextrins (CDs) are a group of cyclic oligosaccharides produced from starch or starch derivatives. They contain six (αCD), seven (βCD), eight (γCD), or more glucopyranose monomers linked via α-1,4-glycosidic bonds. CDs have a truncated cone shape with a hydrophilic outer wall and a less hydrophilic inner wall, the latter forming a more apolar internal cavity. Because of this special architecture, CDs are soluble in water and can simultaneously host lipophilic guest molecules. The major advantage of inclusion into CDs is increased aqueous solubility of such lipophilic substances. Accordingly, we present studies where the complexation of natural compounds such as propolis and dietary plant bioactives (e.g., tocotrienol, pentacyclic triterpenoids, curcumin) with γCD resulted in improved stability, bioavailability, and bioactivity in various laboratory model organisms and in humans. We also address safety aspects that may arise from increased bioavailability of plant extracts or natural compounds owing to CD complexation. When orally administered, α- and βCD—which are inert to intestinal digestion—are fermented by the human intestinal flora, while γCD is almost completely degraded to glucose units by α-amylase. Hence, recent reports indicate that empty γCD supplementation exhibits metabolic activity on its own, which may provide opportunities for new applications.

scholarly journals Design of Sodium Alginate/Gelatin-Based Emulsion Film Fused with Polylactide Microparticles Charged with Plant Extract

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 745 ◽  
Author(s):  
Weronika Prus-Walendziak ◽  
Justyna Kozlowska
Keyword(s):  
Sodium Alginate ◽  
Plant Extract ◽  
Contact Angles ◽  
Polymeric Films ◽  
Solvent Evaporation Method ◽  
Calendula Officinalis ◽  
Flower Extract ◽  
Polymeric Microparticles ◽  
Emulsion Film ◽  
Emulsion Films

This study aimed at designing emulsion films based on sodium alginate, gelatin, and glycerol, and their modification by the addition of lipids (cottonseed oil and beeswax). Film composition with the most promising properties was further modified by the incorporation of polylactide (PLA) microparticles with Calendula officinalis flower extract. PLA microspheres were obtained by the emulsion/solvent evaporation method. The size distribution of oily particles in emulsions was investigated. Mechanical properties, moisture content, UV-Vis spectra, and the color of films were analyzed, while biophysical skin parameters were assessed after their application to the skin. Moreover, the contact angles were measured, and the surface free energy of polymeric films was determined. An investigation of the amount of Calendula officinalis flower extract which can be incorporated into PLA microparticles was performed. The modification of the composition of films significantly influenced their physicochemical properties. The selected active ingredient in the form of plant extract was successfully incorporated into polymeric microparticles that were further added into the developed emulsion film. The condition of the skin after the application of obtained emulsion films improved. The prepared materials, especially containing microparticles with plant extract, can be considered for designing new cosmetic forms, such as cosmetic masks, as well as new topical formulations for pharmaceutical delivery.

Antimycobacterial activity of 2-phenoxy-1-phenylethanone, a synthetic analogue of neolignan, entrapped in polymeric microparticles

2011 ◽  
Vol 38 (3) ◽  
pp. 259-263 ◽  
Author(s):  
Paulo R.R. Minarini ◽  
Ana O. de Souza ◽  
Edson G. Soares ◽  
Lauro E.S. Barata ◽  
Célio L. Silva ◽  
...  
Keyword(s):  
Antimycobacterial Activity ◽  
Synthetic Analogue ◽  
Polymeric Microparticles
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