scholarly journals Challenges and Opportunities of Silk Protein Hydrogels in Biomedical Applications

2022 ◽  
Author(s):  
Junwei Liu ◽  
Xiaodong Ge ◽  
Liang Liu ◽  
Wei Xu ◽  
Rong Shao
Keyword(s):  
Biomedical Applications ◽  
Silk Protein ◽  
Challenges And Opportunities ◽  
Protein Hydrogels

In the context of this era of complementary interdisciplinary advances, the design and preparation of hydrogel materials has been a hot avenue of research for a variety of applications. Silk...

scholarly journals Functional silk fibroin hydrogels: preparation, properties and applications

2021 ◽  
Author(s):  
Haiyan Zheng ◽  
Baoqi Zuo
Keyword(s):  
Silk Fibroin ◽  
Silk Protein ◽  
Current Status ◽  
Protein Hydrogels

This article reviews the current status of the preparation, properties and application of functional silk protein hydrogels.

scholarly journals Stimuli Responsive, Programmable DNA Nanodevices for Biomedical Applications

2021 ◽  
Vol 9 ◽  
Author(s):  
Udisha Singh ◽  
Vinod Morya ◽  
Bhaskar Datta ◽  
Chinmay Ghoroi ◽  
Dhiraj Bhatia
Keyword(s):  
Biomedical Applications ◽  
Recent Progress ◽  
Dna Nanotechnology ◽  
Research Area ◽  
Biological Applications ◽  
Stimuli Responsive ◽  
Future Prospects ◽  
Dna Structures ◽  
Challenges And Opportunities

Of the multiple areas of applications of DNA nanotechnology, stimuli-responsive nanodevices have emerged as an elite branch of research owing to the advantages of molecular programmability of DNA structures and stimuli-responsiveness of motifs and DNA itself. These classes of devices present multiples areas to explore for basic and applied science using dynamic DNA nanotechnology. Herein, we take the stake in the recent progress of this fast-growing sub-area of DNA nanotechnology. We discuss different stimuli, motifs, scaffolds, and mechanisms of stimuli-responsive behaviours of DNA nanodevices with appropriate examples. Similarly, we present a multitude of biological applications that have been explored using DNA nanodevices, such as biosensing, in vivo pH-mapping, drug delivery, and therapy. We conclude by discussing the challenges and opportunities as well as future prospects of this emerging research area within DNA nanotechnology.

scholarly journals Recent Advances in Bioplastics: Application and Biodegradation

Polymers ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 920 ◽  
Author(s):  
Tanja Narancic ◽  
Federico Cerrone ◽  
Niall Beagan ◽  
Kevin E. O’Connor
Keyword(s):  
Biodegradable Polymers ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
State Of The Art ◽  
Weight Ratio ◽  
Challenges And Opportunities ◽  
Single Use ◽  
Art Research ◽  
Degradation Properties ◽  
Design And Application

The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.

scholarly journals Versatile Click-Protein Hydrogels for Biomedical Applications

2017 ◽  
Vol 2 (31) ◽  
pp. 10310-10315
Author(s):  
Gunhye Lee ◽  
Manish Jaiswal ◽  
Akhilesh K. Gaharwar ◽  
Zhilei Chen
Keyword(s):  
Biomedical Applications ◽  
Protein Hydrogels

Progress in Preparation of Silk Fibroin Microspheres for Biomedical Applications

2020 ◽  
Vol 8 (5) ◽  
pp. 358-371
Author(s):  
Shihe Long ◽  
Yun Xiao ◽  
Xingdong Zhang
Keyword(s):  
Cell Culture ◽  
Silk Fibroin ◽  
Biomedical Applications ◽  
Major Protein ◽  
High Mechanical Strength ◽  
Precise Control ◽  
Challenges And Opportunities ◽  
Natural Biomaterial ◽  
Good Biocompatibility ◽  
Near Future

: As a natural biomaterial, silk fibroin (SF) holds great potential in biomedical applications with its broad availability, good biocompatibility, high mechanical strength, ease of fabrication, and controlled degradation. With emerging fabrication methods, nanoand microspheres made from SF have brought about unique opportunities in drug delivery, cell culture, and tissue engineering. For these applications, the size and distribution of silk fibroin particles (SFPs) are critical and require precise control during fabrication. Herein, we review common and emerging SFPs fabrication methods and their biomedical applications, and also the challenges and opportunities for SFPs in the near future. : Lay Summary: The application of silk in textile has an extraordinarily long history and new biomedical applications emerged owing to the good biocompatibility and versatile fabrication options of its major protein component, silk fibroin. With the development of nanotechnology and microfabrication, silk fibroin has been fabricated into nano- or microspheres with precisely controlled shape and distribution. In this review, we summarize common and emerging silk fibroin particle fabrication methods and their biomedical applications, and also discuss their challenges and opportunities in the nearest future.

Tribology-optimised silk protein hydrogels for articular cartilage repair

2015 ◽  
Vol 89 ◽  
pp. 9-18 ◽  
Author(s):  
Maria Parkes ◽  
Connor Myant ◽  
Daniele Dini ◽  
Philippa Cann
Keyword(s):  
Articular Cartilage ◽  
Cartilage Repair ◽  
Silk Protein ◽  
Articular Cartilage Repair ◽  
Protein Hydrogels

Metal nanoparticles triggered persistent negative photoconductivity in silk protein hydrogels

Nanoscale ◽  
2016 ◽  
Vol 8 (14) ◽  
pp. 7695-7703 ◽  
Author(s):  
Narendar Gogurla ◽  
Arun K. Sinha ◽  
Deboki Naskar ◽  
Subhas C. Kundu ◽  
Samit K. Ray
Keyword(s):  
Metal Nanoparticles ◽  
Silk Protein ◽  
Negative Photoconductivity ◽  
Protein Hydrogels

Silk protein-based nanomaterials in drug delivery and biomedical applications

2021 ◽  
pp. 447-463
Author(s):  
Chowdhury Mobaswar Hossain ◽  
Dishari Dutta ◽  
Riddhi Vichare ◽  
Manas R. Biswal ◽  
Kazi Asraf Ali ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Silk Protein
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