scholarly journals Honeycomb Scaffolds Capable of Achieving Barrier Membrane-Free Guided Bone Regeneration

2021 ◽  
Author(s):  
Koichiro Hayashi ◽  
Masaya Shimabukuro ◽  
Ryo Kishida ◽  
Akira Tsuchiya ◽  
Kunio Ishikawa
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Carbonate Apatite ◽  
Bone Augmentation ◽  
Barrier Membrane ◽  
Synthetic Scaffold

Barrier membrane-free guided bone regeneration (GBR) with a synthetic scaffold may resolve the current challenges in vertical bone augmentation. To realize such GBR, we fabricated carbonate apatite honeycomb (HC) scaffolds...

scholarly journals Clinical and histological sequelae of surgical complications in horizontal guided bone regeneration: a systematic review and proposal for management

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
John Rong Hao Tay ◽  
Xiaotong Jacinta Lu ◽  
Wei Ming Clement Lai ◽  
Jia-Hui Fu
Keyword(s):  
Bone Regeneration ◽  
Surgical Complications ◽  
Wound Dehiscence ◽  
Guided Bone Regeneration ◽  
Cochrane Central Register ◽  
Weighted Mean ◽  
Recipient Site ◽  
Barrier Membrane ◽  
Incidence Proportion ◽  
Level Analysis

AbstractIt is not uncommon to encounter post-surgical complications after horizontal guided bone regeneration (GBR). The primary aim of this review was to evaluate the incidence and types of complications that occur after horizontal GBR and propose management strategies to deal with these clinical situations. A secondary aim was to conduct a histomorphometric review of the wound healing process at sites that experienced post-surgical complications after GBR. A keyword search of MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials for studies published in English from January 2015 to January 2020 was conducted for the primary aim and 23 studies were selected. A second search addressing the secondary aim was conducted, and five studies were included. Site-level analysis showed that the weighted mean incidence proportion of minor wound dehiscence and minor infections occurring at the augmented site was 9.9% [95% CI 6.4, 13.9, P < 0.01] and 1.5% [95% CI 0.4, 3.1, P = 0.21) respectively. Patient-level analysis showed minor and major complications occurring at a weighted mean incidence proportion of 16.1% [95% CI 11.9, 20.8, P = 0.01] and 1.6% [95% CI 0.0, 4.7, P < 0.01] respectively, while neurosensory alterations at the donor site was 7.0% [95% CI 1.3, 15.5, P < 0.01]. Subgroup analysis also revealed that the use of block grafts increased the incidence proportion of minor post-surgical complications, whereas a staged GBR procedure increased the incidence proportion of both minor and major post-surgical complications. Although exposure of the barrier membrane is often associated with less bone regeneration and graft resorption, the type of membrane used (resorbable or non-resorbable) had no statistically significant influence on any post-surgical complication. Histologically, a layer of fibrous connective tissue instead of bone is commonly observed at the interface between the native bone at the recipient site and the regenerated bone in cases with membrane exposure after GBR procedure. Minor wound dehiscence was the highest incidence proportion of post-surgical complications. Methods ranging from daily application of antiseptics, use of systemic antimicrobials, regular reviews, and total removal of the non-integrated biomaterials are commonly prescribed to manage these post-surgical complications in attempt to minimise the loss of tissue at the surgical site.

Additive manufacturing to assist prosthetically guided bone regeneration of atrophic maxillary arches

2015 ◽  
Vol 21 (6) ◽  
pp. 705-715 ◽  
Author(s):  
M. Fantini ◽  
F. De Crescenzio ◽  
L. Ciocca ◽  
F. Persiani
Keyword(s):  
Additive Manufacturing ◽  
Bone Regeneration ◽  
Dental Implants ◽  
Surgical Intervention ◽  
Guided Bone Regeneration ◽  
Autogenous Bone ◽  
Bone Augmentation ◽  
Virtual Planning ◽  
Content Type ◽  
Fused Deposition

Purpose – The purpose of this paper is to describe two different approaches for manufacturing pre-formed titanium meshes to assist prosthetically guided bone regeneration of atrophic maxillary arches. Both methods are based on the use of additive manufacturing (AM) technologies and aim to limit at the minimal intervention the bone reconstructive surgery by virtual planning the surgical intervention for dental implants placement. Design/methodology/approach – Two patients with atrophic maxillary arches were scheduled for bone augmentation using pre-formed titanium mesh with particulate autogenous bone graft and alloplastic material. The complete workflow consists of four steps: three-dimensional (3D) acquisition of medical images and virtual planning, 3D modelling and design of the bone augmentation volume, manufacturing of biomodels and pre-formed meshes, clinical procedure and follow up. For what concerns the AM, fused deposition modelling (FDM) and direct metal laser sintering (DMLS) were used. Findings – For both patients, a post-operative control CT examination was scheduled to evaluate the progression of the regenerative process and verify the availability of an adequate amount of bone before the surgical intervention for dental implants placement. In both cases, the regenerated bone was sufficient to fix the implants in the planned position, improving the intervention quality and reducing the intervention time during surgery. Originality/value – A comparison between two novel methods, involving AM technologies are presented as viable and reproducible methods to assist the correct bone augmentation of atrophic patients, prior to implant placement for the final implant supported prosthetic rehabilitation.

scholarly journals Dentin-Derived-Barrier Membrane in Guided Bone Regeneration: A Case Report

Materials ◽  
2021 ◽  
Vol 14 (9) ◽  
pp. 2166
Author(s):  
Jeong-Kui Ku ◽  
In-Woong Um ◽  
Mi-Kyoung Jun ◽  
Il-hyung Kim
Keyword(s):  
Case Report ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Successful Outcome ◽  
Collagen Membrane ◽  
Type I ◽  
Barrier Membrane ◽  
Dentin Matrix ◽  
Demineralized Dentin Matrix ◽  
Demineralized Dentin

An autogenous, demineralized, dentin matrix is a well-known osteo-inductive bone substitute that is mostly composed of type I collagen and is widely used in implant dentistry. This single case report describes a successful outcome in guided bone regeneration and dental implantation with a novel human-derived collagen membrane. The authors fabricated a dentin-derived-barrier membrane from a block-type autogenous demineralized dentin matrix to overcome the mechanical instability of the collagen membrane. The dentin-derived-barrier acted as an osteo-inductive collagen membrane with mechanical and clot stabilities, and it replaced the osteo-genetic function of the periosteum. Further research involving large numbers of patients should be conducted to evaluate bone forming capacity in comparison with other collagen membranes.

Superficial Topography and Porosity of an Absorbable Barrier Membrane Impacts Soft Tissue Response in Guided Bone Regeneration

2010 ◽  
Vol 81 (6) ◽  
pp. 926-933 ◽  
Author(s):  
Ronaldo Barcellos de Santana ◽  
Carolina Miller Leite de Mattos ◽  
Carlos Eduardo Francischone ◽  
Thomas Van Dyke
Keyword(s):  
Soft Tissue ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Tissue Response ◽  
Barrier Membrane ◽  
Soft Tissue Response

scholarly journals The Condensation of Collagen Leads to an Extended Standing Time and a Decreased Pro-inflammatory Tissue Response to a Newly Developed Pericardium-based Barrier Membrane for Guided Bone Regeneration

In Vivo ◽  
2020 ◽  
Vol 34 (3) ◽  
pp. 985-1000 ◽  
Author(s):  
TRISTAN GUELDENPFENNIG ◽  
ALIREZA HOUSHMAND ◽  
STEVO NAJMAN ◽  
SANJA STOJANOVIC ◽  
TADAS KORZINSKAS ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Tissue Response ◽  
Standing Time ◽  
Barrier Membrane ◽  
Inflammatory Tissue

scholarly journals Bone augmentation at peri-implant dehiscence defects comparing a synthetic polyethylene glycol hydrogel matrix vs. standard guided bone regeneration techniques

2016 ◽  
Vol 28 (7) ◽  
pp. e76-e83 ◽  
Author(s):  
Daniel S. Thoma ◽  
Ui-Won Jung ◽  
Jin-Young Park ◽  
Stefan P. Bienz ◽  
Jürg Hüsler ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Bone Augmentation ◽  
Hydrogel Matrix

Investigating the Potential of Amnion-Based Scaffolds as a Barrier Membrane for Guided Bone Regeneration

Langmuir ◽  
2015 ◽  
Vol 31 (31) ◽  
pp. 8642-8653 ◽  
Author(s):  
Wuwei Li ◽  
Guowu Ma ◽  
Bryn Brazile ◽  
Nan Li ◽  
Wei Dai ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Barrier Membrane

scholarly journals Guided Bone Regeneration- A Comprehensive Review

2021 ◽  
Author(s):  
Vineetha Venugopalan ◽  
Anegundi Raghavendra Vamsi ◽  
Santhosh Shenoy ◽  
Karishma Ashok ◽  
Biju Thomas
Keyword(s):  
Bone Regeneration ◽  
Alveolar Bone ◽  
Primary Stability ◽  
Guided Bone Regeneration ◽  
Collagen Membrane ◽  
Bony Defect ◽  
Graft Material ◽  
Bone Augmentation ◽  
Wide Range ◽  
Space Maintenance

Successful implant treatment requires prosthetically driven placement of an implant, primary stability at placement, and careful living bone management. The resorptive changes of alveolar bone are an inevitable process following tooth loss, periodontal disease or trauma which causes bone defects. This results in various aesthetic and functional complications such as soft tissue recession, infection and inflammation. Various methods have been tried and advocated for augmenting these bone deficiencies. Guided Bone Regeneration (GBR) is a successful modality for bone augmentation with a wide range of indications and helps restore the alveolar ridge dimensions. It utilises the principle of Guided Tissue Regeneration (GTR) for space maintenance within a bony defect. Different types of barrier membranes are being utilised along with various bone grafts in GBR. Thorough knowledge regarding the biology of bone is required before the initiation of any bone augmentation procedure. A combination of Collagen Membrane (CM) and graft material was found successful for GBR. Hence, this review focuses on presentation of best available evidence for various aspects of GBR.

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