3D microfluidic cloth-based analytical devices at a single piece of cloth by one-step laser hydrophilicity modification

One-step preparation of antimicrobial silicone materials based on PDMS and salicylic acid: insights from spatially and temporally resolved techniques

npj Biofilms and Microbiomes ◽

10.1038/s41522-021-00223-6 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Luca Barbieri ◽

Ioritz Sorzabal Bellido ◽

Alison J. Beckett ◽

Ian A. Prior ◽

Jo Fothergill ◽

...

Keyword(s):

Salicylic Acid ◽

Laser Scanning ◽

Pathogenic Bacteria ◽

Pharmaceutical Products ◽

Laser Scanning Microscopy ◽

Wound Dressings ◽

Confocal Laser ◽

Vis Spectroscopy ◽

Wide Range ◽

One Step

AbstractIn this work, we introduce a one-step strategy that is suitable for continuous flow manufacturing of antimicrobial PDMS materials. The process is based on the intrinsic capacity of PDMS to react to certain organic solvents, which enables the incorporation of antimicrobial actives such as salicylic acid (SA), which has been approved for use in humans within pharmaceutical products. By combining different spectroscopic and imaging techniques, we show that the surface properties of PDMS remain unaffected while high doses of the SA are loaded inside the PDMS matrix. The SA can be subsequently released under physiological conditions, delivering a strong antibacterial activity. Furthermore, encapsulation of SA inside the PDMS matrix ensured a diffusion-controlled release that was tracked by spatially resolved Raman spectroscopy, Attenuated Total Reflectance IR (ATR-IR), and UV-Vis spectroscopy. The biological activity of the new material was evaluated directly at the surface and in the planktonic state against model pathogenic bacteria, combining confocal laser scanning microscopy, electron microscopy, and cell viability assays. The results showed complete planktonic inhibition for clinically relevant strains of Staphylococcus aureus and Escherichia coli, and a reduction of up to 4 orders of magnitude for viable sessile cells, demonstrating the efficacy of these surfaces in preventing the initial stages of biofilm formation. Our approach adds a new option to existing strategies for the antimicrobial functionalisation of a wide range of products such as catheters, wound dressings and in-dwelling medical devices based on PDMS.

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An Improved Robust Method for Pose Estimation of Cylindrical Parts with Interference Features

Sensors ◽

10.3390/s19102234 ◽

2019 ◽

Vol 19 (10) ◽

pp. 2234 ◽

Cited By ~ 3

Author(s):

Jieyu Zhang ◽

Yuanying Qiu ◽

Xuechao Duan ◽

Kangli Xu ◽

Changqi Yang

Keyword(s):

Laser Scanning ◽

Robust Method ◽

Negative Effects ◽

Profile Fitting ◽

Straight Line ◽

Intelligent Measurement ◽

Cylindrical Parts ◽

Point Set ◽

Aerospace Assembly ◽

Series Of Experiments

Horizontal docking assembly is a fundamental process in the aerospace assembly, where intelligent measurement and adjustable support systems are urgently needed to achieve higher automation and precision. Thus, a laser scanning approach is employed to obtain the point cloud from a laser scanning sensor. And a method of section profile fitting is put forward to solve the pose parameters from the data cloud acquired by the laser scanning sensor. Firstly, the data is segmented into planar profiles by a series of parallel planes, and ellipse fitting is employed to estimate each center of the section profiles. Secondly, the pose of the part can be obtained through a spatial straight line fitting with these profile centers. However, there may be some interference features on the surface of the parts in the practical assembly process, which will cause negative effects to the measurement. Aiming at the interferences, a robust method improved from M-estimation and RANSAC is proposed to enhance the measurement robustness. The proportion of the inner points in a whole profile point set is set as a judgment criterion to validate each planar profile. Finally, a prototype is fabricated, a series of experiments have been conducted to verify the proposed method.

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Enhanced Grain-boundary Emission Lifetime and Additive Induced Crystal Orientation in One-Step Spin-Coated Mixed Cationic (FA/MA) Lead Perovskite Thin Films Stabilized by Zinc Iodide Doping

10.26434/chemrxiv.5484073.v1 ◽

2017 ◽

Author(s):

René M. Williams ◽

Loreta A. Muscarella ◽

Dina Petrova ◽

Rebecca Jorge Cervasio ◽

Aram Farawar ◽

...

Keyword(s):

Thin Films ◽

Laser Scanning ◽

Laser Scanning Microscopy ◽

Confocal Laser ◽

Crystal Formation ◽

Ambient Conditions ◽

Emission Lifetime ◽

Photoluminescence Lifetime ◽

One Step ◽

Zinc Iodide

Mixed cationic lead perovskites containing formamidinium and methylammonium can be stabilized by incorporating ZnI<sub>2 </sub>as an “internal desiccant”. Next to prolonged stability under ambient conditions we show with XRD that the use of an additive, 3-chloropropyl ammonium chloride, influences crystal formation by orienting the crystals. These ~500 nm crystals show individual photoluminescent behavior in thin films and have a longer photoluminescence lifetime at the grain boundaries as compared to the center of the crystal or relative to un-doped materials without the additive made under identical conditions. Charges recombine slower at the edges of the crystals as observed with confocal laser scanning microscopy

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One-Step Fabrication of Cu2O-Cu Catalytic Electrodes with Regular Porous Array by Ultra-Fast Laser Scanning

Journal of Alloys and Compounds ◽

10.1016/j.jallcom.2021.163455 ◽

2021 ◽

pp. 163455

Author(s):

Chaojiang Li ◽

Shenggui Liu ◽

Xin Jin ◽

Zhen Zuo ◽

Huan Yang ◽

...

Keyword(s):

Laser Scanning ◽

One Step ◽

Porous Array

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Microfluidic chip enabled one-step synthesis of biofunctionalized CuInS2/ZnS quantum dots

Lab on a Chip ◽

10.1039/d0lc00202j ◽

2020 ◽

Vol 20 (16) ◽

pp. 3001-3010

Author(s):

Siyi Hu ◽

Butian Zhang ◽

Shuwen Zeng ◽

Liwei Liu ◽

Ken-Tye Yong ◽

...

Keyword(s):

Quantum Dots ◽

Quantum Dot ◽

Microfluidic Chip ◽

Cell Imaging ◽

Robust Method ◽

Imaging Research ◽

One Step

A novel and robust method for synthesizing the biofunctionalized CuInS2/ZnS quantum dots by the microfluidics chips. The synthesized quantum dot materials are easy to be modified by surface targeted biomolecules and can be used in targeted cell imaging research.

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Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis

ACS Applied Materials & Interfaces ◽

10.1021/acsami.7b09717 ◽

2017 ◽

Vol 9 (36) ◽

pp. 30480-30487 ◽

Cited By ~ 34

Author(s):

Tian Tian ◽

Yuan An ◽

Yiping Wu ◽

Yanling Song ◽

Zhi Zhu ◽

...

Keyword(s):

One Step ◽

Analytical Device

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One-step polymer screen-printing for microfluidic paper-based analytical device (μPAD) fabrication

The Analyst ◽

10.1039/c4an01624f ◽

2014 ◽

Vol 139 (24) ◽

pp. 6580-6588 ◽

Cited By ~ 88

Author(s):

Yupaporn Sameenoi ◽

Piyaporn Na Nongkai ◽

Souksanh Nouanthavong ◽

Charles S. Henry ◽

Duangjai Nacapricha

Keyword(s):

Screen Printing ◽

One Step ◽

Analytical Device

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The Effect of Thermocycling on Interfacial Bonding Stability of Self-Etch Adhesives: OCT Study

BioMed Research International ◽

10.1155/2021/5578539 ◽

2021 ◽

Vol 2021 ◽

pp. 1-9

Author(s):

T. A. Bakhsh ◽

A. Turkistani

Keyword(s):

Laser Scanning ◽

Adhesive System ◽

Laser Scanning Microscopy ◽

Confocal Laser ◽

Gap Formation ◽

Swept Source ◽

Before And After ◽

One Step ◽

Self Etch ◽

Filled Composite

Objective. The aim of this study was to monitor the behavior of interfacial gaps formed under different bonded polymeric restorations before and after thermocycling (TC), using swept-source optical coherence tomography (SS-OCT) and confirming the obtained findings with confocal laser scanning microscopy (CLSM). Materials and Methods. Cylindrical class I cavities were prepared in twenty noncarious human premolar teeth ( 1.5 mm depth × 3.5 mm diameter ) and divided randomly into two groups: TS and SN, according to the adhesive system ( n = 10 ). In the TS group, one-step self-etch adhesive Clearfil Tri-S Bond Plus (Kuraray Noritake Dental, Japan) was used, followed by composite restoration using Estelite Sigma Quick (Tokuyama Dental, Japan). In the SN group, the cavities were restored with the two-step self-etch/composite silorane-based resin restoration system (3M ESPE, USA). All specimens were restored in bulk filling technique and cured in accordance with the manufacturers’ instructions. Both groups were imaged under SS-OCT after 24 h and recorded as controls. Then, each group was subjected to thermal challenge using the TC machine (5–55°C) and B-scans were recorded at different TC intervals (2600, 5200, and 10000). In order to confirm the SS-OCT findings, additional specimens were prepared, scanned, and sectioned for CLSM observation. Results. B-scans demonstrated white clusters at the tooth-resin interface that corresponded to the gap location on CLSM images. The TS group showed significantly less gap formation than the SN group before and after TC ( p < 0.001 ). Conclusions. An optimal composite adaptation can be achieved when the bonded restoration comprises a combination of an adhesive containing 10-MDP monomer and a considerable highly filled composite.

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One Step Further: 500 MPa Yield Strength Steel for Offshore Constructions

21st International Conference on Offshore Mechanics and Arctic Engineering, Volume 3 ◽

10.1115/omae2002-28193 ◽

2002 ◽

Cited By ~ 5

Author(s):

F. Hanus ◽

J. Schu¨tz ◽

W. Schu¨tz

Keyword(s):

Yield Strength ◽

Base Material ◽

Steel Grade ◽

The North ◽

Single Piece ◽

Research Programmes ◽

The North Sea ◽

One Step ◽

Haz Toughness ◽

Minimum Yield

Essential savings in time and money can be achieved if the topside of an offshore platform can be installed in a single piece. For the projects Grane and Valhall located in the North Sea this goal could only be met by using steels with a minimum yield strength of 500 MPa. At the same time the steel should be as easily weldable as the 420 MPa TMCP steel that had become a common offshore steel grade in Norway during the last decade. Based on profound experience in TMCP and research programmes on weldability a chemical composition was selected promising to scope the requirements for base material and HAZ. A few plates were first produced and tested successfully. Excellent weldability in terms of HAZ toughness and low preheat was proven through a vast qualification programme and test welds at the yards. In the first part of the 3500 t order for Valhall the process parameters were optimised to achieve stable properties for the whole thickness range from 15 to 80 mm. The development of this steel grade S500M3z, the results and experience gained on the first deliveries shall be presented in the paper.

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