Simultaneous extraction and controlled chemical functionalization of hardwood lignin for improved phenolation

2021 ◽  
Author(s):  
Stefania Bertella ◽  
Jeremy Luterbacher
Keyword(s):  
Natural Abundance ◽  
Promising Candidate ◽  
Simultaneous Extraction ◽  
Chemical Functionalization ◽  
Aromatic Structure

Lignin is a promising candidate for the replacement of fossil-based materials, due to its natural abundance and aromatic structure. This same structure poses major challenges to lignin’s exploitation for material...

Naturally derived sugar-based ionic liquids: an emerging tool for sustainable organic synthesis and chiral recognition

2021 ◽  
Author(s):  
Sabbasani Rajasekhara Reddy ◽  
Priyanka Muthukuru ◽  
P. Krisnaraj ◽  
Jayachandra Rayadurgam
Keyword(s):  
Ionic Liquids ◽  
Organic Synthesis ◽  
Chiral Recognition ◽  
Natural Abundance ◽  
Promising Candidate ◽  
The Past

During the past decade, the synthesis of sugar-based ionic liquids (SILs) from natural sugars has been described as a promising candidate. This is due to their natural abundance in large...

Crystallization of barium hexaferrite

1992 ◽  
Vol 50 (1) ◽  
pp. 362-363
Author(s):  
Chung-kook Lee ◽  
Yolande Berta ◽  
Robert F. Speyer
Keyword(s):  
Size Distribution ◽  
Raw Materials ◽  
Barium Hexaferrite ◽  
Recording Media ◽  
Magnetic Recording Media ◽  
Promising Candidate ◽  
Crystallization Method ◽  
Temperature Heat ◽  
High Density Magnetic Recording ◽  
Temperature Heat Treatment

Barium hexaferrite (BaFe12O19) is a promising candidate for high density magnetic recording media due to its superior magnetic properties. For particulate recording media, nano-sized single crystalline powders with a narrow size distribution are a primary application requirement. The glass-crystallization method is preferred because of the controllability of crystallization kinetics, hence, particle size and size distribution. A disadvantage of this method is the need to melt raw materials at high temperatures with non-reactive crucibles, e.g. platinum. However, in this work, we have shown that crystal growth of barium hexaferrite occurred during low temperature heat treatment of raw batches.

Tuning the phase stability and surface HER activity of 1T′-MoS2 by covalent chemical functionalization

2020 ◽  
Vol 8 (44) ◽  
pp. 15852-15859
Author(s):  
Jiu Chen ◽  
Fuhua Li ◽  
Yurong Tang ◽  
Qing Tang
Keyword(s):  
Phase Stability ◽  
Chemical Functionalization ◽  
The Stability

Chemical functionalization can significantly improve the stability of meta-stable 1T′-MoS2 and tune the surface HER activity.

Concerning the Heterogeneity of the Natural Abundance of 15N in Soil Nitrogen

1981 ◽  
Vol 45 (2) ◽  
pp. 450-451 ◽  
Author(s):  
Daniel H. Kohl ◽  
Barbara A. Bryan ◽  
Georgia Shearer ◽  
Ross A. Virginia
Keyword(s):  
Soil Nitrogen ◽  
Natural Abundance

The Efficacy of Anti-inflammatory Agents in the Prevention of Atrial Fibrillation Recurrences

2020 ◽  
Vol 28 (1) ◽  
pp. 137-151
Author(s):  
Homa Nomani ◽  
Sara Saei ◽  
Thomas P. Johnston ◽  
Amirhossein Sahebkar ◽  
Amir Hooshang Mohammadpour
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Trials ◽  
Therapeutic Option ◽  
General Rule ◽  
Promising Candidate ◽  
Term Basis ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Meta Analyses ◽  
Af Recurrence

: Several studies have indicated an association between inflammation and the recurrence of Atrial Fibrillation (AF), especially after ablation, which is a therapeutic option leading to local inflammation. On the other hand, each AF can lead to another AF, as a general rule. Thus, preventing recurrences of AF is extremely important for patient outcomes. In this paper, we attempted to review the effect of medicinal agents with anti-inflammatory properties on the prevention of AF recurrence. There are several randomized controlled trials (RCTs) and meta-analyses on the prevention of AF recurrence using agents with anti-inflammatory properties, which include steroids, colchicine, statins, and n-3 fatty acids (n-3 FA). Clinical trials evaluating the efficacy of anti-inflammatory drugs in preventing the recurrence of AF led to inconsistent results for corticosteroids, statins and n-3 FAs. These results may be related to the fact that inflammation is not the only factor responsible for triggering recurrences of AF. For example, the presence of structural, mechanical and electrical remodeling could potentially be the most important factors that trigger recurrences of AF but these factors have not been addressed in most of the reported studies. Therefore, future clinical trials are needed to compare the efficacy of anti-inflammatory drugs in AF patients with, or without other factors. For colchicine, a potent anti-inflammatory drug, there are limited studies. However, all the studies investigating colchicine in the context of AF were consistent and promising, especially when colchicine was used on a short-term basis following ablation in patients with paroxysmal AF. Therefore, colchicine could be a promising candidate for further clinical studies involving recurrent AF.

Pharmacokinetics and Tissue Distribution Study of Ferruginol in Wistar Rat by High-performance Liquid Chromatography

2018 ◽  
Vol 15 (1) ◽  
pp. 67-73 ◽  
Author(s):  
Guiyun Cao ◽  
Suqiao Han ◽  
Keke Li ◽  
Li Shen ◽  
Xiaohong Wang ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Mobile Phase ◽  
High Performance ◽  
Wistar Rat ◽  
Freezing And Thawing ◽  
Promising Candidate ◽  
Distribution Study ◽  
Substance Loss ◽  
Tissue Distribution Study ◽  
The Brain

Background: Ferruginol (FRGN) exhibits a broad range of pharmacological properties which make it a promising candidate for chemoprevention. However, little is known about its absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties. Methods: A rapid, sensitive and specific HPLC-DAD method was established to quantify FRGN in the plasma and tissues of Wistar rats. After extraction of FRGN with ethyl acetate (EtOAc), chromatographic separation was performed on a YMC ODS C18 column (250 × 4.6 mm I.D., 5 µm) with a mobile phase consisting of methanol-water (92:8, v/v) at a flow rate of 0.9 mL/min. Detection was conducted with a wavelength of 273 nm at 25 °C. Results: The calibration curves for FRGN were linear in the concentration range of 0.5-20 µg/mL for plasma, 0.5-10 µg/mL for heart, liver, spleen, lung, kidney, stomach, intestine, brain and muscle. After three cycles of freezing and thawing, the concentration variations were within ± 7% of nominal concentrations, indicating no significant substance loss during repeated thawing and freezing. The assay was applied to pharmacokinetic and tissue distribution study in rats. Results suggested that lung, heart, liver, spleen and kidney were the major distribution tissues of FRGN in rats, and FRGN could permeate the blood-brain barrier to distribute in the brain of rats. Conclusion: The information provided by this research is very useful for gaining knowledge of the pharmacokinetic process and tissue distribution of FRGN.

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