Host-guest stoichiometry affects the physicochemical properties and releases kinetics of beta-cyclodextrin/ ferulic acid inclusion complexes

2022 ◽  
Author(s):  
Yuan Li ◽  
Jiayin Huang ◽  
Zhiheng Hu ◽  
Mingyong Zeng ◽  
Zunying Liu ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Ferulic Acid ◽  
Inclusion Complexes ◽  
Release Kinetics ◽  
Precipitation Method ◽  
Beta Cyclodextrin ◽  
Co Precipitation ◽  
Kinetics Of

An inclusion system of embedding ferulic acid into β-cyclodextrin (FACD) with different host-guest stoichiometry was prepared by a co-precipitation method. Then, the physicochemical properties and release kinetics of the FACD...

Antibiotic Loaded Nano Rod Bone Cement for the Treatment of Osteomyelitis

2020 ◽  
Vol 14 ◽  
Author(s):  
Mala Rajendran ◽  
Gazana Iraivan ◽  
Ghayathri BL ◽  
Preetha Mohan ◽  
Keerthana Ravi Chandran ◽  
...  
Keyword(s):  
Bone Cement ◽  
Release Kinetics ◽  
Gompertz Model ◽  
Precipitation Method ◽  
Burst Release ◽  
Excessive Heat ◽  
Pmma Bone Cement ◽  
Co Precipitation ◽  
Average Size ◽  
Kinetics Of

Background: Polymethyl methacrylate (PMMA) bone cement is the clinical gold standard biomaterial for local antibiotic therapy in osteomyelitis. However, it releases 50% of the antibiotic within first three days. It generates excessive heat during polymerization and is non-biodegradable. It must be removed by another operation. The best-known alternative for PMMA is hydroxyapatite. Objective: The present work is focused to synthesize the biodegradable hydroxyapatite in nano form for slow and sustained release of antibiotics and to study the release kinetics of antibiotics. Method: Nano-hydroxyapatite was synthesized by co-precipitation method and characterized by particle size analyser, transmission emission microscopy, fourier transform infrared spectroscopy and energy dispersive X-Ray analysis. Antibiotic loaded nano-hydroxyapatite was prepared as 7 mm beads. The efficiency of drug loaded nano- hydroxyapatite beads against osteomyelitic isolates were evaluated by well diffusion assay. Zero order, first order, second order, Higuchi model Korsmeyer-Peppas and Gompertz model were fit into the release kinetics of antibiotics from hydroxyapatite. Results: Average size of nano-hydroxyapatite was 5 nm. The bactericidal activity exhibited by antibiotic loaded micro sized hydroxyapatite was therapeutic until 10 days only whereas antibiotic loaded nano-hydroxyapatite was therapeutic until 8 weeks. This confirms the burst release of antibiotics from micro sized hydroxyapatite beads. In contrast, the release was slow and sustained upto 8 weeks from nano-hydroxyapatite. Koresmeyer-Peppas model fits into the release kinetics of antibiotics from nano-hydroxyapatite. Conclusion: Nano-hydroxyapatite with Ca/P ratio of 1.78 is suitable for the slow and sustained delivery of antibiotics for 8 weeks.

scholarly journals Inclusion Complex of Plai Oil and β-Cyclodextrin

2016 ◽  
Vol 855 ◽  
pp. 47-53
Author(s):  
Ampa Jimtaisong ◽  
Nisakorn Saewan
Keyword(s):  
Inclusion Complex ◽  
Inclusion Complexes ◽  
Physicochemical Characteristic ◽  
Precipitation Method ◽  
Ir Absorption ◽  
Scanning Calorimetry ◽  
Absorption Bands ◽  
Complex Preparation ◽  
Ft Ir ◽  
Co Precipitation

Inclusion complex of β-cyclodextrin (β-CD) and Plai (Zingiber cassumunar) oil was prepared using a simple co-precipitation method at β-CD to Plai oil in different ratios. The inclusion complexes were characterized using Fourier transform-infrared spectroscopy (FT-IR) and differential scanning calorimetry (DSC). The FT-IR absorption bands of inclusion complex at 3600-3200 cm-1 were broader and shifted toward lower frequencies compared with that of pure β-CD (3359 cm-1). DSC of the inclusion complexes showed two endothermic peaks shifted to lower temperatures (90-100°C and 295-300°C) compared to that of β-CD. The different physicochemical characteristic could be an indication of an embedded guest molecule in the β-CD cavities in the inclusion complex preparation.

Graphene modified Li-rich cathode material Li[Li0.26Ni0.07Co0.07Mn0.56]O2 for lithium ion battery

2014 ◽  
Vol 07 (06) ◽  
pp. 1440013 ◽  
Author(s):  
Xiangjun Li ◽  
Hongxing Xin ◽  
Xiaoying Qin ◽  
Xueqin Yuan ◽  
Di Li ◽  
...  
Keyword(s):  
Electrochemical Impedance ◽  
Rate Capability ◽  
Lithium Ion ◽  
Cycling Performance ◽  
Precipitation Method ◽  
Electrochemical Performances ◽  
Charge Transfer Reaction ◽  
Ion Diffusion ◽  
Co Precipitation ◽  
Kinetics Of

Lithium and Mn rich solid solution materials Li [ Li 0.26 Ni 0.07 Co 0.07 Mn 0.56] O 2 were synthesized by a carbonate co-precipitation method and modified with a layer of graphene. The graphene-modified cathodes exhibit improved rate capability and cycling performance as compared to the bare cathodes. Electrochemical impedance spectroscopy (EIS) analyses reveal that the improved electrochemical performances are due to acceleration kinetics of lithium-ion diffusion and the charge transfer reaction of the graphene-modified cathodes.

scholarly journals Oxidation Kinetics of Propane-Air Mixture over NiCo2O4 Catalyst Emitted from LPG Vehicles

2017 ◽  
Vol 12 (2) ◽  
pp. 191
Author(s):  
Suverna Trivedi ◽  
Ram Prasad ◽  
S. Chadha
Keyword(s):  
Oxidation Kinetics ◽  
Plug Flow ◽  
Tubular Reactor ◽  
Frequency Factor ◽  
Reaction Engineering ◽  
Precipitation Method ◽  
Air Oxidation ◽  
Temperature Ranges ◽  
Co Precipitation ◽  
Kinetics Of

This paper describes the kinetics of catalytic air oxidation of propane. The kinetics data were collected in a plug flow tubular reactor. The experiments were performed over the NiCo2O4 catalyst prepared by co-precipitation method followed by calcination at 400 oC. The kinetic data were collected under the following conditions: 200 mg of catalyst, 2.5 % of propane in air, total flow rate of 60 mL/min, and temperature ranges of 130-170 oC. The data were fitted to the power law rate equation. The activation    energy and frequency factor were found to be 59.3 kJ/g mol and 2.9×108 (mol)0.47.L0.53/g cat.h, respectively. Copyright © 2017 BCREC Group. All rights reservedReceived: 20th November 2016; Revised: 26th February 2017; Accepted: 26th February 2017How to Cite: Trivedi, S., Prasad, R., Chadha, S. (2017). Oxidation Kinetics of Propane-Air Mixture over NiCo2O4 Catalyst Emitted from LPG Vehicles. Bulletin of Chemical Reaction Engineering & Catalysis, 12 (2): 191-196 (doi:10.9767/bcrec.12.2.798.191-196)Permalink/DOI: http://dx.doi.org/10.9767/bcrec.12.2.798.191-196 

scholarly journals Catalytic Performance for Hydrocarbon Production from Syngas on the Promoted Co-Based Hybrid Catalysts; Influence of Pt Contents

2017 ◽  
Vol 12 (3) ◽  
pp. 452 ◽  
Author(s):  
Suk-Hwan Kang ◽  
Jae-Hong Ryu ◽  
Jin-Ho Kim ◽  
Hyo-Sik Kim ◽  
Hee Chul Yang ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Chemical Reaction ◽  
Catalytic Performance ◽  
Reaction Engineering ◽  
Precipitation Method ◽  
Fischer Tropsch ◽  
Hydrocarbon Production ◽  
Hybrid Catalysts ◽  
Co Precipitation ◽  
Different Content

Fischer-Tropsch synthesis (FTS) reaction from syngas was investigated on the Pt-promoted cobalt-based hybrid catalysts prepared by co-precipitation method in a slurry of ZSM-5 (Si/Al=25). The hybrid catalysts were compared with each other for the different content of Pt as a promoter and are characterized using BET, XRD, H2-TPR and NH3-TPD. Their physicochemical properties were correlated with the activity and selectivity of the catalysts. As results, all hybrid catalysts show the C5-C9 yield (%) higher than that of Co-Al2O3/ZSM-5 catalyst. The Pt-promoted hybrid catalysts were found to be more promising towards production of the hydrocarbons of gasoline range and over C10. Copyright © 2017 BCREC Group. All rights reservedReceived: 12nd July 2016; Revised: 31st May 2017; Accepted: 1st June 2017; Available online: 27th October 2017; Published regularly: December 2017How to Cite: Kang, S.H., Ryu, J.H., Kim, J.H., Kim, H.S., Yang, H.C., Chung, D.Y. (2017). Catalytic Performance for Hydrocarbon Production from Syngas on the Promoted Co-Based Hybrid Catalysts; Influence of Pt Contents. Bulletin of Chemical Reaction Engineering & Catalysis, 12 (3): 452-459 (doi:10.9767/bcrec.12.3.592.452-459) 

Synthesis, Characterization and Bioactivity of Chitosan Hydroxyapatite Composite Doped with Strontium

2021 ◽  
Vol 317 ◽  
pp. 217-226
Author(s):  
Ismaila Abdullahi ◽  
Ismail Zainol
Keyword(s):  
Physicochemical Properties ◽  
Calcium Release ◽  
Precipitation Method ◽  
The Novel ◽  
X Ray Diffraction ◽  
X Ray ◽  
Hydroxyapatite Composite ◽  
Novel Material ◽  
Co Precipitation

Chitosan-hydroxyapatite composite doped with strontium was synthesised via in situ co-precipitation method. Physicochemical properties of the composite obtained were analysed using X-ray diffraction (XRD), infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectroscopy (EDX) and Thermogravimetry with differential thermal analysis (DT-TGA). The synthesized composite was subjected to bioactivity studies in simulated body fluid (SBF). The calcium release from the sample in SBF was measured using atomic absorption spectroscopy (AAS). The physicochemical properties and bioactivity of the novel composite was compared with that of hydroxyapatite, strontium doped hydroxyapatite and chitosan hydroxyapatite. The in vitro bioactivity studies of the novel composite showed that it has a higher release of Ca2+ in the SBF compared to the other samples. The novel material was also found to induce more Ca2+ deposition after 28 days of immersion in the SBF. Hence, the novel composite material has the potential to be used as biomaterials for clinical application.

scholarly journals The Optimum Conditions of Carboxymethyl Chitosan Synthesis on Drug Delivery Application and Its Release of Kinetics Study

2017 ◽  
Vol 17 (2) ◽  
pp. 291 ◽  
Author(s):  
Parsaoran Siahaan ◽  
Nadira Cahyaning Mentari ◽  
Ustera Octovindra Wiedyanto ◽  
Dwi Hudiyanti ◽  
Suci Zulaikha Hildayani ◽  
...  
Keyword(s):  
Release Kinetics ◽  
Carboxymethyl Chitosan ◽  
Precipitation Method ◽  
Temperature Reaction ◽  
Matrix System ◽  
Average Value ◽  
Aqueous Solvent ◽  
Na Release ◽  
Kinetics Of

In this paper, carboxymethyl chitosan (CMC) was synthesized and studied as a carrier to encapsulate vitamin (as drug model) and controlled release. Chitosan (CS) is a polycationic derivated from chitin, which suitable for active substance carrier system on biomedical function. CS has good properties such as non-toxic, biodegradable, and biocompatible. However, CS insoluble in an aqueous solvent so CS was modified chemically into CMC. CMC was formed by reacting CS and monochloroacetic acid with sodium hydroxide (NaOH) as a catalyst. Optimation was performed by varying the NaOH concentration during alkalizing the CS and the temperature reaction. The functional group and crystallinity of CS and CMC were estimated by FTIR and XRD. The degree substitution of carboxymethylation has an average value of 0.60. The results show optimum temperature reaction and NaOH concentration were 60 °C and 40% (w/v). The nicotinamide (NA), a hydrophilic vitamin, was loaded within CMC matrix system through in vitro precipitation method. To confirm the encapsulation of NA in CMC and the release kinetics of NA from CMC in distilled water was studied through UV-Vis spectrophotometry. The release profile of NA from CMC matrix system carried out for 3 h and 12 h. The rate of NA release from CMC increases with increasing time and the follows a zero order, Higuchi, and Korsmeyer-Peppas kinetics rules.

scholarly journals Synthesis, Characterization and Applications of MoO3-Fe3O4 Nanocomposite Material

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Madhukar Eknath Navgire ◽  
Akash Nagare ◽  
Ganesh Kale ◽  
Sandesh Bhitre
Keyword(s):  
Heterogeneous Catalyst ◽  
Nanocomposite Material ◽  
Crystalline Size ◽  
Precipitation Method ◽  
Organic Reaction ◽  
Excellent Yield ◽  
Beta Cyclodextrin ◽  
Prepared Material ◽  
Ft Ir ◽  
Co Precipitation

In the present investigation a series of MoO3-Fe3O4 nanocomposite material such as MoO3, Fe3O4, Beta cyclodextrin (b-CD) doped MoO3-Fe3O4 and Graphite doped MoO3-Fe3O4 have been synthesized successfully by co-precipitation method. Synthesized nanomaterials were characterized in detail by XRD, FT-IR, TEM-HRTEM, UV-Vis DRS techniques. The crystalline size was in the range of 10±2 nm. The activity of the prepared material as a heterogeneous catalyst was successfully tested on the organic reaction of synthesis of substituted m-Chloro-Nitrobenzene and it was found to give excellent yield.

scholarly journals FABRICATION OF Mg-Zn-Al HYDROTALCITE AND ITS APPLICATION FOR Pb2+ REMOVAL

2019 ◽  
Vol 59 (3) ◽  
pp. 260-271 ◽  
Author(s):  
Eddy Heraldy ◽  
Fitria Rahmawati ◽  
Dwi Ardiyanti ◽  
Ika Nurmawanti
Keyword(s):  
Second Order ◽  
Precipitation Method ◽  
Molar Ratio ◽  
Adsorption Efficiency ◽  
Molar Ratios ◽  
Isotherm Adsorption ◽  
Langmuir Isotherm Model ◽  
Pseudo Second Order ◽  
Co Precipitation ◽  
Kinetics Of

The fabrication of Mg-Zn-Al Hydrotalcite (HT) was carried out by the co-precipitation method at various molar ratios. The Mg-Zn-Al HT compound at the optimum molar ratio was then calcined to determine the effect of calcination on the Pb2+ adsorption. The kinetics of the adsorption type was determined by applying pseudo first order and pseudo second order kinetics models. Meanwhile, to investigate the adsorption process, the Freundlich and Langmuir equations were applied to determine the adsorption isotherm. The results showed that the optimum Mg-Zn-Al HT was at a molar ratio of 3 : 1 : 1 with an adsorption efficiency of 73.16 %, while Mg-Zn-Al HT oxide increased the adsorption efficiency to 98.12 %. The optimum condition of Pb2+ removal using Mg-Zn-Al HT oxide was reached at pH 5 and a contact time of 30 minutes. The adsorption kinetics follows the pseudo second order kinetics model with a rate constant of 0.544 g/mg·min. The isotherm adsorption follows the Langmuir isotherm model with a maximum capacity of 3.916 mg/g and adsorption energy of 28.756 kJ/mol.

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