Identification and characterization of Crassostrea angulata arginine kinase, a novel allergen that cause cross-reactivity among shellfish

2021 ◽  
Author(s):  
Fei Huan ◽  
Tian-Jiao Han ◽  
Meng Liu ◽  
Meng-Si Li ◽  
Yang Yang ◽  
...  

Oyster is a common food that cause allergy. However, little information is available about its allergens and cross-reactivity. In this study, arginine kinase (AK) was identified as a novel allergen...

2005 ◽  
Vol 280 (49) ◽  
pp. 40731-40748 ◽  
Author(s):  
Hildegard Geyer ◽  
Manfred Wuhrer ◽  
Anja Resemann ◽  
Rudolf Geyer

2009 ◽  
Vol 150 (1) ◽  
pp. 8-14 ◽  
Author(s):  
Zhigang Liu ◽  
Lixin Xia ◽  
Yulan Wu ◽  
Qingyou Xia ◽  
Jiajie Chen ◽  
...  

2002 ◽  
Vol 293 (2) ◽  
pp. 753-758 ◽  
Author(s):  
Yoshihiro Hashimoto ◽  
Hidetoshi Akita ◽  
Mitsunobu Hibino ◽  
Kenjiro Kohri ◽  
Makoto Nakanishi

2014 ◽  
Vol 60 (02) ◽  
pp. 21-27
Author(s):  
Ljubica Suturkova ◽  
Katerina Brezovska ◽  
Ana Poceva-Panovska ◽  
Aleksandra Grozdanova ◽  
Sladjana Knezevic Apostolski

Identification and characterization of antigens present at the human peripheral nerve is a great challenge in the field of neuroimmunology. The latest investigations are focused on the understanding of the biology of glycoconjugates present at the peripheral nerve, and their immunological reactivity. Increased titers of antibodies that recognize carbohydrate determinants of glycoconjugates (glycolipids and glycoproteins) are associated with distinct neuropathic syndromes. There is considerable cross-reactivity among anti-ganglioside antibodies, resulting from shared oligosaccharide epitopes, possibly explaining the overlap in syndromes observed in many affected patients. Sera from patients with neuropathies (GBS, chronic inflammatory demielynating polyneuropathy - CIDP, multifocal motor neuropathy - MMN), cross-react with glycoproteins isolated from human peripheral nerve and from Campylobacter jejuni O:19. The frequency of occurrence of antibodies against these glycoproteins is different, depending of the type of neuropathy. Identification of the cross-reactive glycoproteins and possible additional auto antigens could be useful in laboratory evaluation of peripheral neuropathies and help to develop a more effective therapeutic approach.


1997 ◽  
Vol 6 (2) ◽  
pp. 444-449 ◽  
Author(s):  
Genfa Zhou ◽  
Gopalakrishnan Parthasarathy ◽  
Thayumanasamy Somasundaram ◽  
Andrea Ables ◽  
Lance Roy ◽  
...  

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