Dry heated sorghum BRS 305 hybrid flour as a source of resistant starch and tannins improves inflammation and oxidative stress in Wistar rats fed with a high-fat high-fructose diet

2021 ◽  
Author(s):  
Oscar David Medina Martinez ◽  
Jaqueline Maciel Vieira Theodoro ◽  
Mariana Grancieri ◽  
Renata Celi Lopes Toledo ◽  
Frederico Barros ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Resistant Starch ◽  
Wistar Rats ◽  
Rich Source ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
And Oxidative Stress

This study aimed to evaluate the effect of dry heated sorghum BRS 305 hybrid flour, as a rich source of resistant starch and tannin, on inflammation and oxidative stress in...

Kombuchas from green and black teas reduce oxidative stress, liver steatosis and inflammation, and improve glucose metabolism in Wistar rats fed a high-fat high-fructose diet

2021 ◽  
Author(s):  
Rodrigo Cardoso ◽  
Luiza Dias Moreira ◽  
Mirian Costa ◽  
Renata Celi Lopes Toledo ◽  
Mariana Grancieri ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Metabolism ◽  
Glucose Metabolism ◽  
Wistar Rats ◽  
Liver Steatosis ◽  
Black Tea ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
Green And Black Tea

The aim of this study was to evaluate the effect of green and black tea kombuchas consumption on adiposity, lipid metabolism, liver steatosis, oxidative stress, and inflammation in Wistar rats...

scholarly journals A High-Fat, High-Fructose Diet Induces Antioxidant Imbalance and Increases the Risk and Progression of Nonalcoholic Fatty Liver Disease in Mice

Scientifica ◽  
2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Kanokwan Jarukamjorn ◽  
Nattharat Jearapong ◽  
Charinya Pimson ◽  
Waranya Chatuphonprasert
Keyword(s):  
Oxidative Stress ◽  
Liver Disease ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
High Fat ◽  
Nonalcoholic Fatty Liver ◽  
High Fructose Diet ◽  
High Fructose ◽  
And Oxidative Stress

Excessive fat liver is an important manifestation of nonalcoholic fatty liver disease (NAFLD), associated with obesity, insulin resistance, and oxidative stress. In the present study, the effects of a high-fat, high-fructose diet (HFFD) on mRNA levels and activities of the antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were determined in mouse livers and brains. The histomorphology of the livers was examined and the state of nonenzymatic reducing system was evaluated by measuring the glutathione system and the lipid peroxidation. Histopathology of the liver showed that fat accumulation and inflammation depended on the period of the HFFD-consumption. The levels of mRNA and enzymatic activities of SOD, CAT, and GPx were raised, followed by the increases in malondialdehyde levels in livers and brains of the HFFD mice. The oxidized GSSG content was increased while the total GSH and the reduced GSH were decreased, resulting in the increase in the GSH/GSSG ratio in both livers and brains of the HFFD mice. These observations suggested that liver damage and oxidative stress in the significant organs were generated by continuous HFFD-consumption. Imbalance of antioxidant condition induced by long-term HFFD-consumption might increase the risk and progression of NAFLD.

Dry heated whole sorghum flour (BRS 305) with high tannin and resistant starch improves glucose metabolism, modulates adiposity, and reduces liver steatosis and lipogenesis in Wistar rats fed with a high-fat high-fructose diet

2021 ◽  
Vol 99 ◽  
pp. 103201
Author(s):  
Oscar David Medina Martinez ◽  
Jaqueline Maciel Vieira Theodoro ◽  
Mariana Grancieri ◽  
Renata Celi Lopes Toledo ◽  
Valéria Aparecida Vieira Queiroz ◽  
...  
Keyword(s):  
Glucose Metabolism ◽  
Resistant Starch ◽  
Wistar Rats ◽  
Liver Steatosis ◽  
High Fat ◽  
High Fructose Diet ◽  
Sorghum Flour ◽  
High Fructose

scholarly journals Long-Term Measures of Dyslipidemia, Inflammation, and Oxidative Stress in Rats Fed a High-Fat/High-Fructose Diet

Lipids ◽  
2019 ◽  
Vol 54 (1) ◽  
pp. 81-97 ◽  
Author(s):  
Christine Feillet-Coudray ◽  
Gilles Fouret ◽  
Claire Vigor ◽  
Béatrice Bonafos ◽  
Bernard Jover ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose ◽  
And Oxidative Stress

Imperatorin attenuates cardiac remodelling and dysfunction in high-fat/high-fructose diet-fed rats by modulating oxidative stress, inflammation, and Nrf-2 expression

2022 ◽  
pp. 101728
Author(s):  
Patoomporn Prasartthong ◽  
Poungrat Pakdeechote ◽  
Putcharawipa Maneesai ◽  
Sariya Meephat ◽  
Siwayu Rattanakanokchai ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiac Remodelling ◽  
High Fat ◽  
High Fructose Diet ◽  
High Fructose

Sesame and resistant starch reduce the colon carcinogenesis and oxidative stress in 1,2-dimethylhydrazine-induced cancer in Wistar rats

2014 ◽  
Vol 62 ◽  
pp. 609-617 ◽  
Author(s):  
L. Prado-Silva ◽  
L. Azevedo ◽  
J.A.C. Oliveira ◽  
A.P.M. Moreira ◽  
M. Schmiele ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Resistant Starch ◽  
Wistar Rats ◽  
Colon Carcinogenesis ◽  
And Oxidative Stress

scholarly journals Effect of extracts from selected Kenyan plants on traits of metabolic syndrom in Wistar rats fed a high-fat high fructose diet

2020 ◽  
Vol 19 (10) ◽  
pp. 2137-2146
Author(s):  
Beatrice N. Kiage-Mokua ◽  
Michael De Vrese ◽  
Ina Kraus-Stojanowic ◽  
Annegret Nielsen ◽  
Patrick Kareru ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Traditional Medicine ◽  
Pancreatic Lipase ◽  
Wistar Rats ◽  
Aqueous Extracts ◽  
High Fat ◽  
High Fructose Diet ◽  
Glucosidase Activity ◽  
High Fructose ◽  
Ethanol Extracts

Purpose: To examine the potential of extracts from selected herbs used in African traditional medicine in diabetes patients, and to determine their effect on traits of metabolic syndrome in rats fed a high-fat and high-fructose diet.Methods: Ethanol and aqueous extracts were prepared from Mangifera indica (MI), Lonchocarpus eriocalyx (LE), Urtica massaica (UM), Schkuhria pinnata (SP) and Launaea cornuta (LC). Ethanol extracts (1:100 dilution) were examined for inhibition of pancreatic lipase and α-glucosidase activity invitro. Furthermore, aqueous extracts were administered for 74 days to male Wistar rats fed a high-fat and high-fructose diet to assess their effect on traits of metabolic syndrome.Results: Ethanol extracts showed at least 30 % inhibition of pancreatic lipase in vitro but no effect on α- glucosidase activity. Administration of the aqueous extracts caused significant reduction in liver triglycerides (except for LE). Muscle triglycerides and fat were also reduced, with the most pronounced effect elicited by LE. Urinary glucose excretion and plasma triglycerides, but not hyperinsulinemia and insulin resistance, were reduced by UM compared to control.Conclusion: This exploratory study indicates that UM may be considered a candidate for the prevention and management of type 2 diabetes. Keywords: Kenyan traditional medicine, High-fat diet, High fructose, Insulin resistance, Triglycerides, Diabetes, Liver steatosis

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