Short- and Long-Term Effects of Capsaicin Supplementation on Glycemic Control: A Systematic Review and Meta-Analysis of Controlled Trials

2021 ◽  
Author(s):  
Sahar Foshati ◽  
Sajjad Moradi ◽  
Mohammad Tavassoly ◽  
Mohammad Hossein Rouhani
Keyword(s):  
Systematic Review ◽  
Glucose Metabolism ◽  
Glycemic Control ◽  
Animal Studies ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Long Term Effects ◽  
Beneficial Effects ◽  
Short And Long Term

Background & Aims: Animal studies have shown that capsaicin exerts beneficial effects on glucose metabolism. However, the findings of human studies are contradictory. Therefore, we aimed to conduct a systematic...

scholarly journals Long-term effectiveness of group-based diabetes self-management on glycosylated haemoglobin for people with type 2 diabetes in community: a protocol of systematic review and meta-analysis

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e046692
Author(s):  
Zhang Xia ◽  
Ying-ying Jiang ◽  
Wei-jing Shang ◽  
Hai-jun Guo ◽  
Fan Mao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Density Lipoprotein ◽  
Self Management ◽  
Controlled Trials ◽  
Long Term Effects ◽  
Group Education ◽  
Management Group

IntroductionThe rapid rise in the prevalence of diabetes has a negative impact on patients’ quality of life. Diabetes self-management group education is cost-effective and efficient for patients to control blood glucose. However, there are no consistent standards for self-management group education, and its long-term effects (≥12 months) are unclear. Although a few systematic reviews evaluated the long-term effects, they did not make clear provisions on the content of self-management, and the number and sample size of included studies were small, which may lead to misclassification bias and reporting bias. Therefore, we plan to conduct this systematic review to evaluate the long-term effects of self-management group education and determine the effects of different self-management characteristics on glycosylated haemoglobin (HbA1c).Methods and analysisWe will retrieve Chinese databases (Wanfang, Chinese Hospital Knowledge Warehouse) and English databases (PubMed, ScienceDirect, EMBASE, Web of Science, Bailian Platform, Cochrane Central Register of Controlled Trials, Google Scholar) for randomly controlled trials and cluster randomly controlled trials of which participants are adults with type 2 diabetes mellitus. We will manually search citation lists and trial registries, and consult authors to obtain relevant articles. The retrieval time range will be from the establishment of the database to July 2020 to avoid omitting relevant studies. The primary outcome will be HbA1c. The secondary outcomes will be fasting plasma glucose, postprandial blood glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, systolic blood pressure, diastolic blood pressure, body mass index, waist circumference and death event. Two reviewers will independently conduct article screening and assessment of risk of bias, with a third reviewer arbitrating if necessary. We will give priority to the use of meta-analysis to evaluate the pooled effects of all outcomes. For the outcomes of unrecognised sources of heterogeneity, missing data and less than three related studies, narrative synthesis approach will be used.Ethics and disseminationEthical approval is not required for this systematic review. We plan to present the findings in a peer-reviewed scientific journal, relevant and responsible organisations, and training meetings.PROSPERO registration numberCRD42020209011.

Short- and Long-Term Effects of Parent Training for Preschool Children With or at Risk of ADHD: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 23 (5) ◽  
pp. 423-434 ◽  
Author(s):  
Marie Louise Rimestad ◽  
Rikke Lambek ◽  
Helene Zacher Christiansen ◽  
Esben Hougaard
Keyword(s):  
Systematic Review ◽  
Preschool Children ◽  
Parent Training ◽  
Meta Analysis ◽  
Adhd Symptoms ◽  
Long Term Effects ◽  
Negative Parenting ◽  
Short And Long Term ◽  
Intervention Modality

Objective: The aim of the study was to synthesize the evidence of parent training (PT) as an early intervention for preschool children aged 2.5 to 6 years with ADHD or ADHD symptoms. Method: A systematic review and meta-analysis was conducted. Results: Sixteen studies including 1,003 children were analyzed. Parent-rated outcomes revealed moderate effect sizes (ESs; Hedges’ g) of 0.51 for ADHD symptoms, 0.4 for conduct problems, and 0.63 for negative parenting. Based on independent assessment, results were only significant for negative parenting. Parent-rated outcomes were sustained at follow-ups of 3 to 12 months. Program type, intervention modality, and child diagnostic status did not moderate the effect. Conclusion: PT was partially supported as an efficacious intervention for preschool children with ADHD or ADHD symptoms with moderate ESs on parent-rated outcomes, but no significant results on independently assessed ADHD symptoms.

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