δ-tocotrienol induce nasopharyngeal carcinoma apoptosis and Growth arrest in the CNE1 cells

2021 ◽  
Author(s):  
Junjun Shen ◽  
Tao Yang ◽  
Yiping Tang ◽  
Tianyi Guo ◽  
Ting Guo ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Middle East ◽  
Southeast Asia ◽  
Incidence Rate ◽  
North Africa ◽  
Southern China ◽  
Growth Arrest ◽  
The Arctic ◽  
High Incidence ◽  
High Incidence Rate

Nasopharyngeal carcinoma has a notably high incidence rate in Southern China, Southeast Asia, North Africa, Middle East, and the Arctic. δ-tocotrienol is abundant in cereal and has some health benefits....

scholarly journals ANALYSIS OF INFLUENCE CLIMATE FACTORS OF THE FAR NORTH ON MORBIDITY OF OPHTHALMIC PROFILE AMONG THE CHILDREN’S POPULATION OF THE ARCHIPELAGO NEW LAND

2020 ◽  
Vol 6 (3) ◽  
pp. 12-15
Author(s):  
I. Yu. Mishin ◽  
T. A. Doktorova
Keyword(s):  
Incidence Rate ◽  
Arctic Climate ◽  
The Arctic ◽  
Climate Factors ◽  
Far North ◽  
High Incidence ◽  
High Incidence Rate ◽  
The Impact ◽  
Practical Recommendations

Purpose. To conduct a study of the impact of the Arctic climate on the organ of vision. The results of the study show a high incidence rate according to the ophthalmic profile among the children of the New Land archipelago. Conclusion. Practical recommendations for preventing the development of diseases of the organ of vision in children living in the Arctic are offered.

Clinical characteristics of patients with reproductive dysfunction and benign ovarian neoplasms

2021 ◽  
Vol 50 (4) ◽  
pp. 38-42
Author(s):  
R. G. Gataulina
Keyword(s):  
Incidence Rate ◽  
Clinical Characteristics ◽  
Ovarian Neoplasms ◽  
Reproductive Function ◽  
Research Center ◽  
Medical Sciences ◽  
Reproductive Disorders ◽  
High Incidence ◽  
The Status ◽  
High Incidence Rate

The study reports on the analysis of the anamnestic data of2044 women with reproductive disorders who underwent operative interventions for tumors and tumorlike masses of the ovaries during the period of 1989-1999 in the Research Center of Obstetrics, Gynecology and Perinatology of the Russian Academy of Medical Sciences. A high incidence rate о f complicated anamnesis and the coexisting somatic and extragenital diseases was revealed. The data are presented concerning the status of menstrual and reproductive function of the patients examined.

scholarly journals How to estimate mild Traumatic Brain Injury Incidence? The interest of Emergency Departments data

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
V Bourdin ◽  
L Manitchoko ◽  
P Azouvi ◽  
R Hellmann ◽  
L Josseran
Keyword(s):  
Public Health ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Incidence Rate ◽  
Emergency Departments ◽  
Mild Tbi ◽  
Health Measures ◽  
High Incidence ◽  
High Incidence Rate ◽  
Screening Procedures

Abstract Background Traumatic brain injury (TBI) is a major public health issue, with a significant socio-economic burden. In France, very little is known about TBI epidemiology, and the TBI population is mainly described via studies carried out on the most severe patients. A large number of studies showed that a significant proportion of patients suffer from long-term disability after mild TBI (mTBI). This Post-Concussive Syndrome (PCS) remains poorly known by health professionals. Identifying early prognostic factors for the development of PCS is therefore essential, since it can ensure widespread clinical and economic benefits. This work aims at providing an updated description of the incidence of mild TBI (mTBI) based on data from Emergency Departments (ED) in the Ile-de-France (IDF) region (Paris area). Methods We estimated the mTBI incidence, using mainly data from the OSCOUR (Organisation de la Surveillance Coordonnée des Urgences) database from 01/01/2011 to 31/12/2015. The OSCOUR Network data collection methodology is based on the registration of all patients visiting the emergency services (ED) of participating hospitals. An extrapolation of the proportion of TBI patients visiting an OSCOUR ED to all ED of the IDF allowed us to compute a mTBI Annual Incidence Rate (AIR) in IDF. Results Between 2011 and 2015, 95,910 mTBI patients visited the OSCOUR ED in IDF, and the AIR was estimated at 292.4/100,000 inhabitants (when reported to the French population scale: a total of 196,000 mTBI are supposed to happen each year). Conclusions The surprisingly high incidence rate of mTBI observed in this study requires an evaluation of public health measures to prevent these injuries and reduce their consequences. New screening procedures should be implemented to point out the patients at risk for complications and PCS. Alongside the care aspect, prevention should be developed to reduce the incidence of TBIs, and prevention policies should be assessed by reiterating our evaluation. Key messages Between 2011 and 2015, 95,910 mTBI patients visited the OSCOUR Emergency Departments in Ile de France, and the annual incident rate was estimated at 292.4/100,000 inhabitants. The mTBI high incidence rate requires an evaluation of public health measures to prevent these injuries and reduce their consequences, but also the implementation of new screening procedures.

Quality of drinking water and high incidence rate of esophageal cancer in Golestan province of Iran: a probable link

2011 ◽  
Vol 34 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Behnam Keshavarzi ◽  
Farid Moore ◽  
Ali Najmeddin ◽  
Farah Rahmani ◽  
Ahad Malekzadeh
Keyword(s):  
Esophageal Cancer ◽  
Drinking Water ◽  
Incidence Rate ◽  
High Incidence ◽  
Golestan Province ◽  
High Incidence Rate

scholarly journals Peculiar features of immunogenetic parameters in children with atopic diseases

2018 ◽  
Vol 35 (2) ◽  
pp. 32-36
Author(s):  
Ya. Yu. Illek ◽  
M. L. Vyaznikova ◽  
N. P. Leushina ◽  
I. Yu. Mischenko ◽  
L. L. Ryseva ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Relative Risk ◽  
Incidence Rate ◽  
Bronchial Asthma ◽  
Hla Class I ◽  
Severe Atopic Dermatitis ◽  
Atopic Bronchial Asthma ◽  
High Incidence ◽  
High Incidence Rate ◽  
Age Range

Aim. To determine the peculiarities of distributing antigens of major histocompatibility complex in children with atopic dermatitis and children with bronchial asthma. Materials and methods. Serologic typing of HLA class I-complex antigens and molecular typing of HLA class II-complex antigens was fulfilled in 52 children (age range 5 to 14 years) with disseminated moderate and severe atopic dermatitis and 122 children (age range 5 to 14 years) with moderate and severe atopic bronchial asthma. Results. Among children with atopic dermatitis, there was found high incidence rate of HLA-complex antigens B15, B16, B17, DRB1*13 and DQB1*0602-8, presentation of which was associated with elevation of relative risk for the development of disease by 3.3–8.4 times. In children with atopic bronchial asthma, the observed high incidence rate of HLA-complex antigens A26, B18 and DRB1*17 was associated with rise of relative risk for the development of disease by 3.0–9.1 times.

scholarly journals Analisis Pembiayaan Program Promotif dan Preventif Pemberantasan Demam Berdarah Dengue (DBD) Bersumber Pemerintah di Kota Semarang Tahun 2013-2015

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Nisa Kamila
Keyword(s):  
Local Government ◽  
Incidence Rate ◽  
Government Spending ◽  
Source Function ◽  
Epidemiological Surveillance ◽  
Preventive Program ◽  
Central Java ◽  
High Incidence ◽  
High Incidence Rate ◽  
Improve Planning

AbstrakSelama tahun 2010-2014, Kota Semarang selalu termasuk dalam peringkat tiga besar Incidence Rate Deman Berdarah Dengue (DBD) di Provinsi Jawa Tengah. Penelitian ini bertujuan menganalisis pembiayaan program pemberantasan DBD bersumber pemerintah pada tahun 2013-2015 dan kesenjangan sumberdaya. Pendekatan akun biaya kesehatan (health account) digunakan untuk menelusuri pembiayaan menurut sumber, fungsi, dan penyedia layanan. Hasil studi menunjukkan bahwa total belanja program DBD bersumber APBD tahun 2013 adalah Rp. 4.018.927.020,- meningkat sebesar 101% pada tahun 2014 dan meningkat sebesar 218% pada tahun 2015. Belanja terbesar pada program pemberantasan DBD adalah untuk kegiatan surveilans epidemiologi dan pengendalian penyakit menular. Tidak terdapat kesenjangan antara ketersediaan sumber daya (berdasarkan belanja kesehatan program pemberantasan DBD) dengan kebutuhan program (berdasarkan perhitungan kebutuhan metode SPM). Disarankan agar perencanaan program lebih berfokus pada kegiatan promotif dan preventif. AbstractIn 2010–2014, Semarang was involved as the big three city with high incidence rate of dengue in Central Java province. This study aimed to analyze the financing by the local government for Dengue preventive program in 2013-2015, as well as the resources gap.The health account approach was used to analyze spending by source, function, and provider. Total local government spending for dengue in 2013 were IDR 4.018.927.020,- increased by 101% in 2014 and increased by 218% in 2015. The largest expenditure for Dengue Preventive program is epidemiological surveillance and infectious disease control. There was no gap between available resources and requires program according to SPM. The study suggested to improve planning by focusing on the direct activities such as promotive and preventive.

Rising carbon dioxide is decreasing nutrition in crops and endangering health among the less wealthy

2019 ◽  
Author(s):  
Matthew Smith ◽  
Samuel S. Myers
Keyword(s):  
Carbon Dioxide ◽  
Middle East ◽  
Nutritional Status ◽  
Southeast Asia ◽  
Human Health ◽  
North Africa ◽  
Nutrient Content ◽  
South And Southeast Asia ◽  
Co2 Levels ◽  
Carbon Dioxide Levels

Carbon dioxide levels are rising globally. The increasing CO2 levels reduce the concentration of nutrients in many of the crops that are consumed worldwide (wheat, rice, barley, maize, legumes, and potatoes). The larger effects for human health are concentrated in regions that heavily rely on these crops for their nutrition such as South and Southeast Asia, North Africa, and the Middle East. Because these effects are likely to be hidden, we should better monitor the nutritional status of populations as well as crop nutrient content over the coming decades.

Nasopharyngeal Cancer

2017 ◽  
Author(s):  
Ellen T. Chang ◽  
Allan Hildesheim
Keyword(s):  
Southeast Asia ◽  
Squamous Cell ◽  
Southern China ◽  
Nasopharyngeal Cancer ◽  
Great Majority ◽  
Incidence Rates ◽  
The Arctic ◽  
Histologic Subtype ◽  
Barr Virus ◽  
Low Incidence

The main epithelial malignancy arising in the nasopharynx is nasopharyngeal carcinoma (NPC). Although rare throughout most of the world, NPC has a unique geographic distribution, with high-risk endemic areas in southern China and parts of Southeast Asia, intermediate incidence rates elsewhere in Southeast Asia, North Africa, the Arctic, the Middle East, and among Asian and Pacific Islander migrants, and very low risk in other areas. The great majority of NPC cases worldwide are non-keratinizing tumors; these predominate in endemic, high-incidence areas and comprise up to half of tumors in low-incidence populations. The other histologic subtype of NPC, keratinizing squamous cell carcinoma, accounts for 40%–50% of cases in low-incidence areas. Infection with Epstein-Barr virus (EBV) is a necessary but not sufficient cause of non-keratinizing NPC, though it is more weakly associated with keratinizing squamous cell tumors. Tobacco smoking increases the risk of both subtypes.

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