Redox-induced target-dependent ratiometric fluorescence sensing strategy and logic gate operation for detection of α-glucosidase activity and its inhibitor

2021 ◽  
Author(s):  
Xucan Yuan ◽  
Yi Sun ◽  
Pengfei Zhao ◽  
Longshan Zhao ◽  
Zhili Xiong

A target-dependent ratiometric fluorescence sensing strategy was designed and fabricated based on redox reaction for highly sensitive detection of α-glucosidase (α-Glu) activity and its inhibitor. In this study, silicon quantum...

2017 ◽  
Vol 53 (98) ◽  
pp. 13137-13140 ◽  
Author(s):  
Yuan Yuan ◽  
Xiao-Sheng Yan ◽  
Xiao-Rui Li ◽  
Jin-Lian Cao ◽  
Zhao Li ◽  
...  

Dipeptide-based amidothiourea (azapeptides) bearing folded β-turn structures were employed to build beacon-like fluorescent sensors signalled by pyrene exciplex or excimer dual emission to allow highly sensitive ratiometric fluorescence sensing of an anion able to bind to the structural moiety placed within the turn structure.


The Analyst ◽  
2018 ◽  
Vol 143 (23) ◽  
pp. 5728-5735 ◽  
Author(s):  
Nannan Wang ◽  
Yue Wang ◽  
Jinhua Gao ◽  
Xin Ji ◽  
Jinling He ◽  
...  

The probe could respond to Cys/Hcy, exhibiting a ratiometric fluorescence response through intramolecular displacement with the amino group displacing the sulfur function to form amino-substituted BODIPY.


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