Coordination capabilities of bis-(2-pyridyl)amides in the field of divalent germanium, tin and lead compounds

2021 ◽  
Author(s):  
Jan Zechovský ◽  
Ondřej Mrózek ◽  
Maksim Samsonov ◽  
Roman Jambor ◽  
Aleš Růžička ◽  
...  

Bis-(2-pyridyl)amides show a rich coordination variability toward heavier tetrylenes including the formation of ate complexes with different types of lithium coordination.

PEDIATRICS ◽  
1996 ◽  
Vol 97 (6) ◽  
pp. 916-917
Author(s):  
Mary Beth Miller ◽  
Steven C. Curry ◽  
Donald B. Kunkel ◽  
Patricia Arreola ◽  
Ernest Arvizu ◽  
...  

Lead compounds are used as coloring agents for numerous products. Two cases of children with elevated blood lead concentrations encountered by the authors suggested that pool cue chalk may serve as a source of environmental lead. The objective of this study was to determine lead content of various brands and colors of pool cue chalk. Atomic absorption analyses were conducted of 23 different types of pool cue chalk for lead content. Three of 23 types of pool cue chalk contained more than 7000 ppm (mg/kg) lead: one manufacturer's green and tangerine chalk and another manufacturer's green chalk. It was concluded that some brands of pool cue chalk contain relatively large amounts of lead and could contribute to childhood lead poisoning.


2017 ◽  
Vol 12 (12) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Leonid A. Kaluzhskiy ◽  
Tatsiana V. Shkel ◽  
Natalia V. Ivanchina ◽  
Alla A. Kicha ◽  
Irina P. Grabovec ◽  
...  

Lanosterol 14α-demethylases (hemoproteins of the cytochrome P450(51) family) are involved in biosynthesis of different membrane sterols, including animal cholesterol, fungal ergosterol and C24-modified plant and protozoa sterols. In this study we have investigated 10 structural analogs of lanosterol isolated from echinoderms belonging to the class Asteroidea as potential ligands (competitive inhibitors) of human and Candida albicans cytochromes P450(51). The study was performed using the surface plasmon resonance method, spectrophotometric titration and enzyme assay. Among the compounds tested we found several selective ligands for human and Candida albicans cytochromes. Between selective ligands of the human lanosterol 14α-demethylase we found two novel inhibitors of this enzyme: henricioside H1 and levisculoside G from Henricia derjugini. With due consideration of obtained data, we conclude that marine organisms from the class Asteroidea can be a valuable source of new lead compounds for creation of selective inhibitors of cytochromes P450(51) family with less side effects due to their selective action on these enzymes in different types of organisms.


2013 ◽  
Vol 733 ◽  
pp. 71-78 ◽  
Author(s):  
Martin Novotný ◽  
Zdeňka Padělková ◽  
Jaroslav Holeček ◽  
Aleš Růžička
Keyword(s):  

1996 ◽  
Vol 241 (2) ◽  
pp. 9-10 ◽  
Author(s):  
J. Barrau ◽  
G. Rima ◽  
T. El Amraoui
Keyword(s):  

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