Process intensification using immobilized enzymes for the development of white biotechnology

2021 ◽  
Vol 11 (6) ◽  
pp. 1994-2020
Author(s):  
Harshada M. Salvi ◽  
Ganapati D. Yadav
Keyword(s):  
Ionic Liquids ◽  
Process Intensification ◽  
Flow Chemistry ◽  
Immobilized Enzymes ◽  
Hydrodynamic Cavitation ◽  
Future Directions ◽  
White Biotechnology

Process intensification of biocatalysed reactions using different techniques such as microwaves, ultrasound, hydrodynamic cavitation, ionic liquids, microreactors and flow chemistry in various industries is critically analysed and future directions provided.

scholarly journals Biodiesel production process intensification using a rotor-stator type generator of hydrodynamic cavitation

2016 ◽  
Vol 33 ◽  
pp. 220-225 ◽  
Author(s):  
Daniele Crudo ◽  
Valentina Bosco ◽  
Giuliano Cavaglià ◽  
Giorgio Grillo ◽  
Stefano Mantegna ◽  
...  
Keyword(s):  
Production Process ◽  
Process Intensification ◽  
Hydrodynamic Cavitation ◽  
Biodiesel Production

scholarly journals The spinning cloth disc reactor for immobilized enzymes: A new process intensification technology for enzymatic reactions

2013 ◽  
Vol 221 ◽  
pp. 407-417 ◽  
Author(s):  
Xudong Feng ◽  
Darrell Alec Patterson ◽  
Murat Balaban ◽  
Guillaume Fauconnier ◽  
Emma Anna Carolina Emanuelsson
Keyword(s):  
Process Intensification ◽  
Immobilized Enzymes ◽  
Enzymatic Reactions ◽  
New Process

scholarly journals Automated High-Pressure Atline Analysis of Photo-High-P,T Vitamin D3 Microfluidic Synthesis

2021 ◽  
Vol 3 ◽  
Author(s):  
Marc Escribà-Gelonch ◽  
Nghiep Nam Tran ◽  
Volker Hessel
Keyword(s):  
High Performance ◽  
Process Analytical Technology ◽  
Control Process ◽  
Process Intensification ◽  
Flow Chemistry ◽  
Critical Parameters ◽  
Primary Responsibility ◽  
Feasible Option ◽  
Relevant Topic ◽  
Pressure Independent

Process analytical technology has become a relevant topic in both industry and academia as a mechanism to control process quality by measuring critical parameters; being mainly applied in pharmaceutical industry. An emerging topic is process monitoring with subsequent process automation in flow chemistry using inline, online and atline analyzers. Flow chemistry often deliberately and favorably uses harsh conditions (termed Novel Process Windows) to achieve process intensification which raises the need for sampling under these conditions. This demands for setting in place a stabilization of the sample before exposing it to the processing. Ignoring this may result in being unable to use inline/online analytics and posing the need for a separation step before quantitative analysis, leaving atline analysis as the only feasible option. That means that sampling and connected operations need also to be automated. This is where this study sets in, and this is enabled by a modified high-performance liquid chromatography (HPLC) autosampler coupled to the photo-high-p,T flow synthesis of vitamin D3. It shows that sampling variables, such as decompression speed, can be even more critical in terms of variability of results than process variables such as concentration, pressure, and temperature. The modification enabled the autosampler fully automated and unattended sampling from the reactor and enabled pressure independent measurements with 89% accuracy, >95% reproducibility, and >96% repeatability, stating decompression speed as the primary responsibility for measurements’ uncertainty.

Inorganic nanoparticle synthesis in flow reactors – applications and future directions

2020 ◽  
Vol 5 (9) ◽  
pp. 1619-1641
Author(s):  
Olga Długosz ◽  
Marcin Banach
Keyword(s):  
Nanoparticle Synthesis ◽  
Flow Chemistry ◽  
Future Directions ◽  
Flow Reactors ◽  
Inorganic Nanoparticle ◽  
Continuous Methods ◽  
Inorganic Nanomaterials

The use of flow technologies for obtaining nanoparticles can play an important role in the development of ecological and sustainable processes for obtaining inorganic nanomaterials, and the continuous methods are part of the Flow Chemistry trend.

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