Cationic cyclization reactions with alkyne terminating groups: a useful tool in biomimetic synthesis

2022 ◽  
Author(s):  
Olaya García-Pedrero ◽  
Félix Rodríguez
Keyword(s):  
Organic Synthesis ◽  
Biomimetic Synthesis ◽  
Cyclization Reactions ◽  
Cationic Cyclization

Cyclization reactions through cationic intermediates have become a highly valuable tool in organic synthesis. The use of alkynes as the terminating group in this type of cationic processes offers wide...

Tin-Mediated Radical Cyclization Reactions

2021 ◽  
Vol 25 ◽  
Author(s):  
Saima malik ◽  
Aditya G. Lavekar ◽  
Bimal Krishna Banik
Keyword(s):  
Organic Compounds ◽  
Organic Synthesis ◽  
Biological Significance ◽  
Radical Cyclization ◽  
Organic Reactions ◽  
Cyclization Reactions ◽  
Complex Molecules ◽  
Radical Chemistry ◽  
Wide Range

: The radical was first come into existence in 1900 by Gomberg, where the triphenylmethane radical was explored. Thus, even to date, two centuries have seen radical chemistry as the methodology of preference in organic synthesis. Due to the fascinating nature of the radical-mediated cyclization reactions, it always caught the eye of organic chemists for the synthesis of novel organic compounds with diverse stereochemistry. Moreover, the development of radical methods further proves beneficial for the synthesis by providing atom- and step-economical methods to complex molecules. Among these, where radical chemistry has been employed, the use of tin-based radical annulation is the most common and widely used field for the synthesis of a wide range of organic reactions with medicinal importance. In this review, we compiled recent tin-mediated radical cyclization reactions toward the synthesis of molecules of biological significance.

Organolithium-mediated cyclization reactions: a practical way to access hetero- and carbocycles

2017 ◽  
Vol 41 (16) ◽  
pp. 7824-7835 ◽  
Author(s):  
Mukhtiar Ahmed ◽  
Muhammad Moazzam Naseer
Keyword(s):  
Organic Synthesis ◽  
Cyclization Reactions ◽  
Molecular Skeleton

Cyclization reactions are considered as one of the most important reactions in organic synthesis due to the fact that natural molecules contain cyclic components either as part of the molecule or molecular skeleton.

Cyclization Reactions of Dianions in Organic Synthesis

ChemInform ◽  
2004 ◽  
Vol 35 (51) ◽  
Author(s):  
Peter Langer ◽  
Walter Freiberg
Keyword(s):  
Organic Synthesis ◽  
Cyclization Reactions
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