Immobilisation and stabilisation of glycosylated enzymes on boronic acid-functionalised silica nanoparticles

2021 ◽  
Author(s):  
Seyed Amirabbas Nazemi ◽  
Magdalena Olesińska ◽  
Cinzia Pezzella ◽  
Simona Varriale ◽  
Chia-Wei Lin ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Boronic Acid ◽  
Boronate Esters ◽  
Enzyme Immobilisation

We report a method of glycosylated enzyme immobilisation and stabilisation based on the formation of boronate esters between a surface-attached boronate and the enzyme glycans, followed by the growth of an organosilica layer of controlled thickness.

Deprotection of pinacolyl boronate esters by transesterification with polystyrene–boronic acid

2004 ◽  
Vol 45 (35) ◽  
pp. 6657-6660 ◽  
Author(s):  
Thomas E. Pennington ◽  
Cynantya Kardiman ◽  
Craig A. Hutton
Keyword(s):  
Boronic Acid ◽  
Boronate Esters

Deprotection of Pinacolyl Boronate Esters by Transesterification with Polystyrene—Boronic Acid.

ChemInform ◽  
2004 ◽  
Vol 35 (49) ◽  
Author(s):  
Thomas E. Pennington ◽  
Cynantya Kardiman ◽  
Craig A. Hutton
Keyword(s):  
Boronic Acid ◽  
Boronate Esters

The Structural Basis for Hydrolysis Resistance in the Esters of (2-Formylphenyl)boronic Acid 2,4-Dinitrophenylhydrazones

2002 ◽  
Vol 67 (7) ◽  
pp. 1084-1094 ◽  
Author(s):  
Michael P. Groziak ◽  
Paul D. Robinson
Keyword(s):  
Boronic Acid ◽  
Intramolecular Interaction ◽  
Boronic Acids ◽  
Membered Ring ◽  
Structural Basis ◽  
Previous Suggestion ◽  
Boronate Esters ◽  
X Ray ◽  
Hydrolysis Resistance ◽  
Electron Deficiency

Under conditions that typically afford bicyclic boron heterocycles directly, (2-formylphenyl)boronic acids react with 2,4-dinitrophenylhydrazine in ethanol to give highly waterresistant diethyl boronate esters. Two such 2,4-dinitrophenylhydrazones were prepared and their X-ray crystal structures determined. Contrary to a previous suggestion that their unusual stability is due to an intramolecular N→B coordination giving a six-membered BN2C3 ring system based on a (Z)-hydrazone, these compounds instead were found to be (E)-hydrazones internally stabilized by a weak intramolecular interaction between nitrogen and boron from within a five-membered ring. Further study revealed that the electron deficiency of the starting hydrazine reagent plays a key role in determining the structure of the hydrazone isolated, and that the water-resistant boronate esters can be hydrolyzed under forcing conditions to the boronic acids.

Renewable boronic acid affiliated glycerol nano-adsorbents for recycling enzymatic catalyst in biodiesel fuel production

2018 ◽  
Vol 54 (88) ◽  
pp. 12475-12478 ◽  
Author(s):  
Lei Liu ◽  
Gaojian Ma ◽  
Min Zeng ◽  
Wei Du ◽  
Jinying Yuan
Keyword(s):  
Silica Nanoparticles ◽  
Boronic Acid ◽  
Biodiesel Production ◽  
Biodiesel Fuel ◽  
Release Behavior ◽  
Ph Responsive ◽  
Fuel Production ◽  
Enzymatic Catalyst

Renewable boronic acid affiliated silica nanoparticles exhibit pH-responsive glycerol adsorption/release behavior to recycle free lipases in biodiesel production.

Synthesis of boronic acid-functionalized molecularly imprinted silica nanoparticles for glycoprotein recognition and enrichment

2014 ◽  
Vol 2 (6) ◽  
pp. 637-643 ◽  
Author(s):  
Zian Lin ◽  
Lixiang Sun ◽  
Wei Liu ◽  
Zhiwei Xia ◽  
Huanghao Yang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Boronic Acid ◽  
Molecularly Imprinted ◽  
Molecularly Imprinted Silica

scholarly journals Gelating Abilities of Two-Component System of Catecholic Derivatives and a Boronic Acid

Gels ◽  
2019 ◽  
Vol 5 (4) ◽  
pp. 45 ◽  
Author(s):  
Akihiko Tsuge ◽  
Ryota Kamoto ◽  
Daisuke Yakeya ◽  
Koji Araki
Keyword(s):  
Boronic Acid ◽  
Noncovalent Interactions ◽  
Three Dimensional ◽  
Two Component System ◽  
Boronate Esters ◽  
Component System ◽  
Practical Applications ◽  
Unit Form ◽  
Two Component ◽  
Low Molecular Weight Organogelators

In the last two decades, various kinds of the low-molecular-weight organogelators (LMOGs) have been investigated in terms of technological applications in various fields as well as their fundamental scientific properties. The process of gelation is generally considered to arise from immobilization of the solvents in the three-dimensional networks formed by the assembly of gelator molecules through weak intermolecular noncovalent interactions. From these points of view a huge number of organogelators have been developed so far. In the course of our research on LMOGs we have noticed a mixture of two gelators could show a different trend in gelation compared to the single gelator. It is well known that the catecholic moiety easily forms cyclic boronate esters with the boronic acid. Thus, we have investigated the two-component system based on cyclic boronate esters formed by the catechols and a boronic acid in terms of the control of gelation capability. Basic gelation properties of the constituent catecholic gelators have also been clarified. The catecholic gelators with the amide unit form no gel by addition of the boronic acid. In contrast, the catecholic gelators with the glutamic acid moiety improve their gelation abilities by mixing with the boronic acid. Furthermore, the gelation ability of the catecholic gelators having the urea unit is maintained after addition of the boronic acid. It has been found that gelation abilities of the catecholic gelators are highly affected by addition of the boronic acid. In terms of practical applications some gels can be obtained by on-site mixture of two kinds of solutions.

Click synthesis of boronic acid-functionalized molecularly imprinted silica nanoparticles with polydopamine coating for enrichment of trace glycoproteins

2015 ◽  
Vol 7 (23) ◽  
pp. 10026-10031 ◽  
Author(s):  
Lixiang Sun ◽  
Danhong Lin ◽  
Guowei Lin ◽  
Ling Wang ◽  
Zian Lin
Keyword(s):  
Silica Nanoparticles ◽  
Boronic Acid ◽  
Molecularly Imprinted ◽  
Click Synthesis ◽  
Molecularly Imprinted Silica

Novel boronic acid-functionalized molecularly imprinted silica nanoparticles with polydopamine coating were prepared and applied to the recognition and enrichment of glycoproteins.

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