Ruthenium(II)-catalyzed C–H activation and (4+2) annulation of aromatic hydroxamic acid esters with allylic amides

2021 ◽  
Author(s):  
Chandan Kumar Giri ◽  
Suman Dana ◽  
Mahiuddin Baidya
Keyword(s):  
Hydroxamic Acid ◽  
Olefin Coupling ◽  
Directing Group ◽  
Acid Esters

A (4+2) annulation under Ru(II)-catalysis is reported using aromatic hydroxamic acid esters as oxidizing directing group and allylic amides as unactivated olefin coupling partners, delivering a wide variety of aminomethyl...

Nonenzymatic Catalysis by Metal Ions and Phosphoric Acid Esters of Hydroxamic Acid Formation

1980 ◽  
Vol 35 (6) ◽  
pp. 727-730
Author(s):  
Oemer Saygin ◽  
Peter Decker
Keyword(s):  
Amino Acids ◽  
Phosphoric Acid ◽  
Metal Ions ◽  
Inorganic Phosphate ◽  
Hydroxamic Acid ◽  
Hydroxamic Acids ◽  
Bivalent Ions ◽  
No Release ◽  
Catalytic Effects ◽  
Acid Esters

Abstract Nonenzymatic catalysis by bivalent ions of Be, Mg, Ca, Zn, Mn, Ni and Co and bioorganic phosphates of the formation of hydroxamic acids from acetate or amino acids has been studied systematically. Increased yields of hydroxamate were observed at particular combinations of reactants. The most prominent increase (ca. 15-fold) was found with acetate and Ni++, and with a combination of ATP and Be++. Among others especially ribose-5-phosphate and glucose-5-phosphate enhanced yields in the presence of most metal ions. Since no release of inorganic phosphate was observed, this effect cannot be interpreted as an evidence for intermediate transhosphorylation reactions; it may also result from simple catalytic effects of metal sugar complexes.

Intramolecular cyclization of a diruthenium complex: insight into the mechanism of heteroatom-directed intramolecular C–H/olefin coupling reactions

2015 ◽  
Vol 44 (28) ◽  
pp. 12507-12510 ◽  
Author(s):  
Dawei Gong ◽  
Bowen Hu ◽  
Jing Shi ◽  
Dafa Chen
Keyword(s):  
Double Bond ◽  
Transition Metal ◽  
Intramolecular Cyclization ◽  
Ruthenium Complex ◽  
Coupling Reactions ◽  
Olefin Coupling ◽  
Directing Group ◽  
Metal Catalyzed ◽  
Diruthenium Complex ◽  
Insight Into

The reactivities of a trinuclear ruthenium complex with 1,5-hexadiene suggest that the CC double bond is the second directing group in transition-metal catalyzed heteroatom-directed intramolecular C–H/olefin coupling reactions.

1832-P: Palmitic Acid Esters of Hydroxy Stearic Acids Reduce Endogenous Glucose Production through GPR43 Activation

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1832-P
Author(s):  
ANNA SANTORO ◽  
PENG ZHOU ◽  
YAN ZHU ◽  
ODILE D. PERONI ◽  
ANDREW T. NELSON ◽  
...  
Keyword(s):  
Palmitic Acid ◽  
Glucose Production ◽  
Endogenous Glucose Production ◽  
Endogenous Glucose ◽  
Acid Esters
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