Photoredox-Catalyzed Hydrosulfamoylation of Styrenes and Its Application in the Novel Synthesis of Naratriptan

2021 ◽  
Author(s):  
Mingjun Zhang ◽  
Miaomiao Chen ◽  
Xin Ding ◽  
Jin Kang ◽  
Yongyue Gao ◽  
...  
Keyword(s):  
The Novel ◽  
Novel Synthesis ◽  
Aryl Olefins

The sulfonamidation of diverse aryl olefins is facile access to synthesize alkylsulfonamides. Here we report a novel protocol utilizing radical-mediated addition and thiol-assisted strategy to achieve hydrosulfamoylation of diverse styrenes...

Novel synthesis of 1,5-disubstituted-1,2,3-triazolines catalysed by Zepto magnetic microspheres under the influence of a rotating magnetic field

2019 ◽  
Vol 97 (3) ◽  
pp. 163-168 ◽  
Author(s):  
Priyanka Sharma ◽  
Srinivasu V. Vallabhapurapu ◽  
Wei H. Ho ◽  
Nanjundaswamy M. Hemmaragala
Keyword(s):  
Magnetic Field ◽  
Magnetic Force ◽  
Rotating Magnetic Field ◽  
Magnetic Microspheres ◽  
The Novel ◽  
Aryl Azides ◽  
Alkyl Aryl ◽  
Novel Synthesis ◽  
Bead Diameter ◽  
Magnetic Poles

The novel reactor has been designed to perform chemical reactions under the influence of a magnetic field generated by alternating magnetic poles as a function of time. The system was successfully employed to synthesize a series of 1,5-disubstituted-1,2,3-triazolines via the regioselective [3 + 2] cycloaddition reactions between alkyl/aryl azides and nitroolefins catalysed by Zepto (para magnetic ultra-blue carboxy functionalized) microspheres (bead diameter 2.5 μm). All of the reactions went smoothly without any adverse effect on nitro, cyano, thienyl, hydroxy, halogens, and ether functions at 25 ± 2 °C and afforded 82%–99% pure products at a magnetic field of 18.99 mT and an exposure time of 180–240 min. The influence of the magnetic force exerted on the magnetic materials was found to enhance the catalytic activity of microspheres. The catalyst could easily be separated by simple centrifugation, which could be reused for at least 15 runs with no loss in activity.

scholarly journals The synthesis of iminothiophenone-fused quinolines and evaluation of their serendipitous reactions

RSC Advances ◽  
2016 ◽  
Vol 6 (95) ◽  
pp. 92235-92240 ◽  
Author(s):  
Morteza Shiri ◽  
Zeinab Faghihi ◽  
Hossein A. Oskouei ◽  
Majid M. Heravi ◽  
Shima Fazelzadeh ◽  
...  
Keyword(s):  
The Novel ◽  
Novel Synthesis

The novel synthesis of tricyclic 2-(cyclohexylimino)thieno[2,3-b]quinolin-3(2H)-ones from the reaction of 2-mercaptoquinoline-3-carbaldehydes and isocyanides in methanol without the use of any additive is described.

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