Interfacial tetrazine click chemistry mediated assembly of multifunctional colloidosomes

2021 ◽  
Author(s):  
Meenakshi Pahwa ◽  
Priyanka Jain ◽  
Nilanjana Das Saha ◽  
Chandrabhas Narayana ◽  
Sarit Agasti
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry ◽  
Cross Link ◽  
Tetrazine Ligation

We demonstrate that tetrazine ligation chemistry can be employed to cross-link and assemble gold nanoparticles at the water-oil interface to create plasmonic colloidosomes. These biocompatible colloidosomes exhibit size tunability via...

scholarly journals Recombinant DNA technology and click chemistry: a powerful combination for generating a hybrid elastin-like-statherin hydrogel to control calcium phosphate mineralization

2017 ◽  
Vol 8 ◽  
pp. 772-783 ◽  
Author(s):  
Mohamed Hamed Misbah ◽  
Mercedes Santos ◽  
Luis Quintanilla ◽  
Christina Günter ◽  
Matilde Alonso ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Click Chemistry ◽  
Recombinant Dna ◽  
Fibrillar Structure ◽  
Cross Link ◽  
Recombinant Dna Technology ◽  
Peptide Epitope ◽  
Phosphate Mineralization ◽  
Potential Applications ◽  
Dna Technology

Understanding the mechanisms responsible for generating different phases and morphologies of calcium phosphate by elastin-like recombinamers is supreme for bioengineering of advanced multifunctional materials. The generation of such multifunctional hybrid materials depends on the properties of their counterparts and the way in which they are assembled. The success of this assembly depends on the different approaches used, such as recombinant DNA technology and click chemistry. In the present work, an elastin-like recombinamer bearing lysine amino acids distributed along the recombinamer chain has been cross-linked via Huisgen [2 + 3] cycloaddition. The recombinamer contains the SNA15 peptide domains inspired by salivary statherin, a peptide epitope known to specifically bind to and nucleate calcium phosphate. The benefit of using click chemistry is that the hybrid elastin-like-statherin recombinamers cross-link without losing their fibrillar structure. Mineralization of the resulting hybrid elastin-like-statherin recombinamer hydrogels with calcium phosphate is described. Thus, two different hydroxyapatite morphologies (cauliflower- and plate-like) have been formed. Overall, this study shows that crosslinking elastin-like recombinamers leads to interesting matrix materials for the generation of calcium phosphate composites with potential applications as biomaterials.

Visual detection of single-nucleotide polymorphisms and DNA methyltransferase based on cation-exchange of CuS nanoparticles and click chemistry of functionalized gold nanoparticles

2016 ◽  
Vol 52 (90) ◽  
pp. 13261-13264 ◽  
Author(s):  
X. R. Zhang ◽  
Y. Zhang ◽  
F. T. Chen ◽  
Y. Li ◽  
S. S. Zhang
Keyword(s):  
Gold Nanoparticles ◽  
Single Nucleotide Polymorphisms ◽  
Cation Exchange ◽  
Click Chemistry ◽  
Dna Methyltransferase ◽  
Visual Detection ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Functionalized Gold Nanoparticles

A novel biosensor was developed based on the cation-exchange of CuS nanoparticles (NPs) and Cu(i)-based click chemistry of functionalized gold nanoparticles (AuNPs).

scholarly journals Monovalent maleimide functionalization of gold nanoparticles via copper-free click chemistry

2014 ◽  
Vol 50 (86) ◽  
pp. 13157-13160 ◽  
Author(s):  
D. J. Nieves ◽  
N. S. Azmi ◽  
R. Xu ◽  
R. Lévy ◽  
E. A. Yates ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Growth Factor ◽  
Click Chemistry ◽  
Fibroblast Growth Factor ◽  
Michael Addition ◽  
The Self ◽  
Fibroblast Growth Factor 2 ◽  
Fibroblast Growth ◽  
Self Assembled Monolayer ◽  
Self Assembled

A single maleimide was installed onto the self-assembled monolayer of gold nanoparticles by copper-free click chemistry. Simple covalent biofunctionalisation is demonstrated by coupling fibroblast growth factor 2 and an oligosaccharide in a 1 : 1 stoichiometry by thiol-Michael addition.

scholarly journals Design of liquid-crystalline gold nanoparticles by click chemistry

2012 ◽  
Vol 48 (16) ◽  
pp. 2183 ◽  
Author(s):  
Sylvain Mischler ◽  
Sebastiano Guerra ◽  
Robert Deschenaux
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry ◽  
Liquid Crystalline

scholarly journals Recent applications of click chemistry for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles

2018 ◽  
Vol 14 ◽  
pp. 11-24 ◽  
Author(s):  
Vivek Poonthiyil ◽  
Thisbe K Lindhorst ◽  
Vladimir B Golovko ◽  
Antony J Fairbanks
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry ◽  
Biological Function ◽  
Detection Methods ◽  
Disease States ◽  
Gold Core ◽  
Novel Therapeutic Strategies ◽  
Function Activity ◽  
Nanoparticle Core ◽  
Made In

Glycoscience, despite its myriad of challenges, promises to unravel the causes of, potential new detection methods for, and novel therapeutic strategies against, many disease states. In the last two decades, glyco-gold nanoparticles have emerged as one of several potential new tools for glycoscientists. Glyco-gold nanoparticles consist of the unique structural combination of a gold nanoparticle core and an outer-shell comprising multivalent presentation of carbohydrates. The combination of the distinctive physicochemical properties of the gold core and the biological function/activity of the carbohydrates makes glyco-gold nanoparticles a valuable tool in glycoscience. In this review we present recent advances made in the use of one type of click chemistry, namely the azide–alkyne Huisgen cycloaddition, for the functionalization of gold nanoparticles and their conversion to glyco-gold nanoparticles.

Bionanoconjugation via Click Chemistry:  The Creation of Functional Hybrids of Lipases and Gold Nanoparticles

2006 ◽  
Vol 17 (6) ◽  
pp. 1373-1375 ◽  
Author(s):  
Jennifer L. Brennan ◽  
Nikos S. Hatzakis ◽  
T. Robert Tshikhudo ◽  
Valdemaras Razumas ◽  
Shamkant Patkar ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry ◽  
The Creation

Constructing Metal Nanoparticle Multilayers with Polyphenylene Dendrimer/Gold Nanoparticles via “Click” Chemistry

Langmuir ◽  
2013 ◽  
Vol 29 (12) ◽  
pp. 3943-3949 ◽  
Author(s):  
Huiqiang Li ◽  
Zhanxian Li ◽  
Linzhi Wu ◽  
Yuna Zhang ◽  
Mingming Yu ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry ◽  
Metal Nanoparticle

“Click” Chemistry Mildly Stabilizes Bifunctional Gold Nanoparticles for Sensing and Catalysis

2014 ◽  
Vol 20 (27) ◽  
pp. 8363-8369 ◽  
Author(s):  
Na Li ◽  
Pengxiang Zhao ◽  
Na Liu ◽  
María Echeverria ◽  
Sergio Moya ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Click Chemistry
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