Highly selective two-photon fluorescence off-on probe for imaging tyrosinase activity in living cells and tissues

2021 ◽  
Author(s):  
Yixin Cui ◽  
Sang Jun Park ◽  
Xiaofeng Wu ◽  
Rui Wang ◽  
Sujie Qi ◽  
...  
Keyword(s):  
High Selectivity ◽  
Living Cells ◽  
Tyrosinase Activity ◽  
Live Cells ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

A coumarin-based two-photon (TP) fluorescence off-on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enables probe to successfully image tyrosinase activity in live cells and...

A novel two-photon fluorescent probe for hydrogen sulfide in living cells using an acedan–NBD amine dyad based on FRET process with high selectivity and sensitivity

2017 ◽  
Vol 41 (14) ◽  
pp. 6769-6774 ◽  
Author(s):  
Yao Tang ◽  
Guo-Fang Jiang
Keyword(s):  
Hydrogen Sulfide ◽  
Linear Response ◽  
High Selectivity ◽  
Fluorescence Probe ◽  
Living Cells ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

The first NBD amine based two-photon fluorescence probe L using a FRET strategy was developed for the H2S detecting in vitro and in vivo. The probe L not only afforded high selectivity and sensitivity for H2S detecting, but also dispalyed a linear response to H2S with a low detection limit 24 nM.

Two-Photon Fluorescence and MR Bio-imaging of Endogenous H2O2 in Tumor Microenvironment by a Dual-Mode Nanoprobe

2021 ◽  
Author(s):  
Hongmei Zhong ◽  
Shengrong Yu ◽  
Bingqian Li ◽  
Kangdi He ◽  
Dian Li ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Tumor Microenvironment ◽  
Mr Imaging ◽  
High Selectivity ◽  
Carbon Quantum Dots ◽  
Dual Mode ◽  
Two Photon ◽  
Bio Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Dual-mode bio-imaging nanoprobe TP-CQDs@MnO2, based two-photon carbon quantum dots and MnO2, has been developed for two-photon fluorescence and MR imaging of endogenous H2O2 in tumor microenvironment, which achieved high selectivity,...

A water-soluble two-photon fluorescence chemosensor for ratiometric imaging of mitochondrial viscosity in living cells

2016 ◽  
Vol 4 (35) ◽  
pp. 5907-5912 ◽  
Author(s):  
Meng Zhao ◽  
Yingzhong Zhu ◽  
Jian Su ◽  
Qian Geng ◽  
Xiaohe Tian ◽  
...  
Keyword(s):  
Living Cells ◽  
Water Soluble ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

We report a novel water-soluble ratiometric TPEF chemosensor EIN that is specifically responsive and singularly sensitive to mitochondria viscosity in living cells.

Open-Chain Crown-Ether-Derived Two-Photon Fluorescence Probe for Real-Time Dynamic Biopsy of Mercury Ions

2017 ◽  
Vol 70 (6) ◽  
pp. 705
Author(s):  
Chibao Huang ◽  
Daohai Zhang ◽  
Junle Qu ◽  
Xiaonan Liu ◽  
Guanglian Zhao ◽  
...  
Keyword(s):  
Water Solubility ◽  
Fluorescence Probe ◽  
Stokes Shift ◽  
Cell Permeability ◽  
Photon Absorption ◽  
Live Cells ◽  
Open Chain ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

A novel two-photon fluorescence probe for Hg2+ derived from bis(styryl)terephthalonitrile, as a two-photon fluorophore, and bis[2-(2-hydroxyethyl sulfanyl) ethyl]amino group (ionophore), as a novel Hg2+ ligand, was developed. The probe possesses small molecule size, large two-photon absorption cross-section (1067 GM) in H2O, non-cytotoxic effect, long wavelength emission at 588 nm, large Stokes shift (121 nm), excellent photostability, high water solubility, good cell permeability, and pH insensitivity in the biologically relevant range. The probe can selectively detect Hg2+ ions in live cells and living tissues without interference from other metal ions and the membrane-bound probes, and its quenching constant is 8.73 × 105 M–1.

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